Seong‐Cheol Park
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View article: Alteration of the Antifungal Action Mechanism Due to Structural Changes in the Antimicrobial Peptide, HnMc
Alteration of the Antifungal Action Mechanism Due to Structural Changes in the Antimicrobial Peptide, HnMc Open
The rapid induction of drug resistance is considered a fatal drawback of conventional antibiotics and requires the continuous development of new antibiotics. Accordingly, antibacterial peptides (AMPs) have attracted interest as next-genera…
View article: Differential response of SNU-1826 colon cells on the autophagy, ER stress, and inflammation during the regulation of microplastic internalization
Differential response of SNU-1826 colon cells on the autophagy, ER stress, and inflammation during the regulation of microplastic internalization Open
The internalization mechanism of microplastics (MPs) into human cells has attracted considerable attention because these mechanisms are closely related to the physical and chemical properties of MPs. This study examined the response of hum…
View article: Antifungal Action of Arabidopsis thaliana TCP21 via Induction of Oxidative Stress and Apoptosis
Antifungal Action of Arabidopsis thaliana TCP21 via Induction of Oxidative Stress and Apoptosis Open
The realm of antimicrobial proteins in plants is extensive but remains relatively uncharted. Understanding the mechanisms underlying the action of plant antifungal proteins (AFPs) holds promise for antifungal strategies. This study aimed t…
View article: Potent Antifungal Functions of a Living Modified Organism Protein, CP4-EPSPS, against Pathogenic Fungal Cells
Potent Antifungal Functions of a Living Modified Organism Protein, CP4-EPSPS, against Pathogenic Fungal Cells Open
Various proteins introduced into living modified organism (LMO) crops function in plant defense mechanisms against target insect pests or herbicides. This study analyzed the antifungal effects of an introduced LMO protein, 5-enolpyruvylshi…
View article: Author Correction: High-harmonic generation from a flat liquid-sheet plasma mirror
Author Correction: High-harmonic generation from a flat liquid-sheet plasma mirror Open
View article: High-harmonic generation from a flat liquid-sheet plasma mirror
High-harmonic generation from a flat liquid-sheet plasma mirror Open
View article: Anti-Biofilm Effects of Rationally Designed Peptides against Planktonic Cells and Pre-Formed Biofilm of Pseudomonas aeruginosa
Anti-Biofilm Effects of Rationally Designed Peptides against Planktonic Cells and Pre-Formed Biofilm of Pseudomonas aeruginosa Open
Biofilms are resistant to antibiotics and are a major source of persistent and recurring infections by clinically important pathogens. Drugs used for biofilm-associated infections are limited because biofilm-embedded or biofilm-matrix bact…
View article: Antifungal and Anti-Inflammatory Activities of PS1-2 Peptide against Fluconazole-Resistant Candida albicans
Antifungal and Anti-Inflammatory Activities of PS1-2 Peptide against Fluconazole-Resistant Candida albicans Open
Clinically, fungal pneumonia rarely occurs in adults, and invasive fungal infections can cause substantial morbidity, and mortality due to sepsis and septic shock. In the present study, we have designed peptides that exhibit potent antifun…
View article: Potent Anti-Inflammatory Effects of a Helix-to-Helix Peptide against Pseudomonas aeruginosa Endotoxin-Mediated Sepsis
Potent Anti-Inflammatory Effects of a Helix-to-Helix Peptide against Pseudomonas aeruginosa Endotoxin-Mediated Sepsis Open
Although considerable scientific research data is available for sepsis and cytokine storm syndrome, there is a need to develop new treatments or drugs for sepsis management. Antimicrobial peptides (AMPs) possess anti-bacterial and anti-inf…
View article: Design of Antimicrobial Peptides with Cell-Selective Activity and Membrane-Acting Mechanism against Drug-Resistant Bacteria
Design of Antimicrobial Peptides with Cell-Selective Activity and Membrane-Acting Mechanism against Drug-Resistant Bacteria Open
Antimicrobial peptides (AMPs) can combat drug-resistant bacteria with their unique membrane-disruptive mechanisms. This study aimed to investigate the antibacterial effects of several membrane-acting peptides with amphipathic structures an…
View article: Functional Characterization of an Arabidopsis Profilin Protein as a Molecular Chaperone under Heat Shock Stress
Functional Characterization of an Arabidopsis Profilin Protein as a Molecular Chaperone under Heat Shock Stress Open
Profilins (PFNs) are actin monomer-binding proteins that function as antimicrobial agents in plant phloem sap. Although the roles of Arabidopsis thaliana profilin protein isoforms (AtPFNs) in regulating actin polymerization have already be…
View article: Deep-Learning-Based Cerebral Artery Semantic Segmentation in Neurosurgical Operating Microscope Vision Using Indocyanine Green Fluorescence Videoangiography
Deep-Learning-Based Cerebral Artery Semantic Segmentation in Neurosurgical Operating Microscope Vision Using Indocyanine Green Fluorescence Videoangiography Open
There have been few anatomical structure segmentation studies using deep learning. Numbers of training and ground truth images applied were small and the accuracies of which were low or inconsistent. For a surgical video anatomy analysis, …
View article: Antifungal Mechanism of Vip3Aa, a Vegetative Insecticidal Protein, against Pathogenic Fungal Strains
Antifungal Mechanism of Vip3Aa, a Vegetative Insecticidal Protein, against Pathogenic Fungal Strains Open
Discovering new antifungal agents is difficult, since, unlike bacteria, mammalian and fungal cells are both eukaryotes. An efficient strategy is to consider new antimicrobial proteins that have variety of action mechanisms. In this study, …
View article: Erratum to: Antibacterial Effects of Amino Acids-grafted Water-soluble Chitosan against Drug-resistant Bacteria
Erratum to: Antibacterial Effects of Amino Acids-grafted Water-soluble Chitosan against Drug-resistant Bacteria Open
View article: Antifungal Effect of A Chimeric Peptide Hn-Mc against Pathogenic Fungal Strains
Antifungal Effect of A Chimeric Peptide Hn-Mc against Pathogenic Fungal Strains Open
It is difficult to identify new antifungal agents because of their eukaryotic nature. However, antimicrobial peptides can well differentiate among cell types owing to their variable amino acid content. This study aimed to investigate the a…
View article: Intermediate die profile design for high-precision production of rectangular stainless-steel bars via new tandem drawing process
Intermediate die profile design for high-precision production of rectangular stainless-steel bars via new tandem drawing process Open
View article: Correction to: Long-term Outcome of Angioplasty Using a Wingspan Stent, Post-Stent Balloon Dilation and Aggressive Restenosis Management for Intracranial Arterial Stenosis
Correction to: Long-term Outcome of Angioplasty Using a Wingspan Stent, Post-Stent Balloon Dilation and Aggressive Restenosis Management for Intracranial Arterial Stenosis Open
View article: Functional Characterization of a Rice Thioredoxin Protein OsTrxm and Its Cysteine Mutant Variant with Antifungal Activity
Functional Characterization of a Rice Thioredoxin Protein OsTrxm and Its Cysteine Mutant Variant with Antifungal Activity Open
Although there are many antimicrobial proteins in plants, they are not well-explored. Understanding the mechanism of action of plant antifungal proteins (AFPs) may help combat fungal infections that impact crop yields. In this study, we ai…
View article: Enhanced Antifungal Activity of Engineered Proteins via Swapping between Thioredoxin H2 and H3
Enhanced Antifungal Activity of Engineered Proteins via Swapping between Thioredoxin H2 and H3 Open
Thioredoxins (Trxs) are proteins that act as antioxidants by facilitating the reduction of other proteins and are highly conserved in all organisms. Plant H-type Trx isoforms have different structures and perform multiple functions. Previo…
View article: Erratum to: Antibacterial Effects of Amino Acids-grafted Water-soluble Chitosan against Drug-resistant Bacteria
Erratum to: Antibacterial Effects of Amino Acids-grafted Water-soluble Chitosan against Drug-resistant Bacteria Open
View article: Functional Mechanisms Underlying the Antimicrobial Activity of the Oryza sativa Trx-like Protein
Functional Mechanisms Underlying the Antimicrobial Activity of the Oryza sativa Trx-like Protein Open
Plants are constantly subjected to a variety of environmental stresses and have evolved regulatory responses to overcome unfavorable conditions that might reduce or adversely change a plant’s growth or development. Among these, the regulat…
View article: In Reply: Systematic Stereotactic Error Reduction Using a Calibration Technique in Single-Brain-Pass and Multitrack Deep Brain Stimulations
In Reply: Systematic Stereotactic Error Reduction Using a Calibration Technique in Single-Brain-Pass and Multitrack Deep Brain Stimulations Open
To the Editor: We are grateful for the interest in our article.1 Stereotactic accuracy is one of the most important issues in stereotactic neurosurgery and there are various image-guided applications including image-guided manual or roboti…
View article: One-step synthesis of gene carrier via gamma irradiation and its application in tumor gene therapy
One-step synthesis of gene carrier via gamma irradiation and its application in tumor gene therapy Open
The simple grafting process mediated via gamma irradiation is a promising method for synthesizing gene carriers.
View article: Olecranon Fractures Have Features of Osteoporotic Fracture
Olecranon Fractures Have Features of Osteoporotic Fracture Open
This study demonstrated that olecranon fractures have osteoporotic features, including age-dependent low bone attenuation and low-energy trauma as the predominant cause of injury. Our results suggest that osteoporosis evaluation should be …
View article: Characteristic as a Gene Delivery System of Water Soluble Chitosan Conjugated with Cationic Peptide
Characteristic as a Gene Delivery System of Water Soluble Chitosan Conjugated with Cationic Peptide Open
Recently gene delivery has been designed newly using bioactive biomaterial and applied in the various field by many researchers. In this study, we proposed a new gene delivery system which has the capability of targeting effect in the spec…
View article: The Effectiveness of New Power Generation and Energy Demand Reduction to Achieve Greenhouse Gas Reduction Goals in Building Area
The Effectiveness of New Power Generation and Energy Demand Reduction to Achieve Greenhouse Gas Reduction Goals in Building Area Open
Since the massive power outages that hit across the nation in September 2011, a growing imbalance between energy supply and demand has led to a severe backup power shortage. To overcome the energy crisis which is annually repeated, a polic…
View article: Penetration and Splitting of Optic Nerve by Tuberculum Sellae Meningioma
Penetration and Splitting of Optic Nerve by Tuberculum Sellae Meningioma Open
Preservation of the optic nerves is an important issue in the resection of tuberculum sellae meningiomas. We report the case of a patient whose optic nerve was penetrated by a tuberculum sellae meningioma. During surgery, a bulging tumor w…
View article: Antimicrobial Action of Water-Soluble β-Chitosan against Clinical Multi-Drug Resistant Bacteria
Antimicrobial Action of Water-Soluble β-Chitosan against Clinical Multi-Drug Resistant Bacteria Open
Recently, the number of patients infected by drug-resistant pathogenic microbes has increased remarkably worldwide, and a number of studies have reported new antibiotics from natural sources. Among them, chitosan, with a high molecular wei…
View article: A Study on Water Repellent Effectiveness of Natural Oil-Applied Soil as a Building Material
A Study on Water Repellent Effectiveness of Natural Oil-Applied Soil as a Building Material Open
This study was performed to investigate the water repellent effectiveness of natural oil-applied soil when it is used as a building material. Natural oil types such as olive oil, bean oil, perilla oil and linseed oil, which are being used …