Francis Fagnani
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View article: Prognostic impact of the number and Temporality of heart failure Hospitalisations: Analysis of a National healthcare database
Prognostic impact of the number and Temporality of heart failure Hospitalisations: Analysis of a National healthcare database Open
In patients with reduced LVEF, both recent and recurrent HF hospitalisations are strong predictors of mortality and rehospitalisation. These two simple markers identify highly vulnerable patients and should trigger intensified follow-up, o…
View article: Clinical and Economic Burden of Patients With Haemophilia A and B in France: Analysis of a Nationwide Claims Database
Clinical and Economic Burden of Patients With Haemophilia A and B in France: Analysis of a Nationwide Claims Database Open
Introduction There are few data on healthcare resource use and related costs of French haemophilia A (HA) and B (HB) patients. Aims This study aimed to describe the profile of HA and HB patients, current disease management, clinical burden…
View article: Treatment Patterns and Survival in Patients with Intermediate, Advanced, or Terminal Stage of Hepatocellular Carcinoma in France over the Period 2015-2017: A Real-Life Study
Treatment Patterns and Survival in Patients with Intermediate, Advanced, or Terminal Stage of Hepatocellular Carcinoma in France over the Period 2015-2017: A Real-Life Study Open
Background. The prognosis of patients with hepatocellular carcinoma (HCC) not eligible to curative treatment is poor. Little information is available on treatment modalities and outcomes of these patients in everyday practice. The aim of t…
View article: Epidemiology and disease burden of tuberous sclerosis complex in France: A population‐based study based on national health insurance data
Epidemiology and disease burden of tuberous sclerosis complex in France: A population‐based study based on national health insurance data Open
Objective Tuberous sclerosis complex (TSC) is a rare multisystem disorder, often associated with epilepsy. This retrospective study aimed to identify patients with TSC, including those with epilepsy, from a French healthcare claims databas…
View article: Three-year clinical outcomes in patients with rheumatoid arthritis treated with certolizumab pegol: results from the observational ECLAIR study
Three-year clinical outcomes in patients with rheumatoid arthritis treated with certolizumab pegol: results from the observational ECLAIR study Open
This is the first prospective, observational study of an anti-TNF treatment in France. The results confirm the effectiveness and safety profile of certolizumab pegol treatment in patients with RA in a real-world setting.
View article: Economic burden of coronary artery disease or peripheral artery disease in patients at high risk of ischemic events in the French setting: a claims database analysis
Economic burden of coronary artery disease or peripheral artery disease in patients at high risk of ischemic events in the French setting: a claims database analysis Open
Aims: Estimate the direct costs of high-risk patients presenting with coronary artery disease (CAD) or peripheral artery disease (PAD) in France.Materials and methods: This retrospective cohort study used a representative claims database, …
View article: Early non-response to certolizumab pegol in rheumatoid arthritis predicts failure to achieve low disease activity at 1 year: data from a prospective observational study
Early non-response to certolizumab pegol in rheumatoid arthritis predicts failure to achieve low disease activity at 1 year: data from a prospective observational study Open
Objective To evaluate the performance of clinical criteria for predicting late treatment failure in patients with early non-response to certolizumab pegol (CZP). Methods A protocol-specified analysis of interim data from ECLAIR, a 3-year l…
View article: Quality of life and utility decrement associated with Clostridium difficile infection in a French hospital setting
Quality of life and utility decrement associated with Clostridium difficile infection in a French hospital setting Open
The impact on quality of life of CDI episodes is major and translates in a substantial QALY loss despite their short duration.
View article: Migraine burden and costs in France: a nationwide claims database analysis of triptan users
Migraine burden and costs in France: a nationwide claims database analysis of triptan users Open
Objectives: To estimate the burden of migraine in the population of French patients identified as specific migraine acute treatment users compared to a control group. Methods: A cross-sectional retrospective analysis was performed on the E…
View article: Migraine burden and costs in france: a nationwide claims database analysis of triptan users
Migraine burden and costs in france: a nationwide claims database analysis of triptan users Open
Objectives: To estimate the burden of migraine in the population of French patients identified as specific migraine acute treatment users as compared to a control group. Methods: A cross-sectional retrospective analysis was performed on th…
View article: Impact of Clostridium difficile Infection on Patients’ Quality of Life: a French Hospital Prospective Study
Impact of Clostridium difficile Infection on Patients’ Quality of Life: a French Hospital Prospective Study Open
Background Few data are available on the impact of episodes of Clostridium difficile infection (CDI) on quality of life. The Cdiff32, a new specific health-related quality of life questionnaire recently validated, allows such a measurement…