L. Bryan Ray
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View article: Green synthesis of silver-chitosan nanocomposite exhibits promising antibiofilm properties against pathogenic bacteria Escherichia coli and Staphylococcus aureus
Green synthesis of silver-chitosan nanocomposite exhibits promising antibiofilm properties against pathogenic bacteria Escherichia coli and Staphylococcus aureus Open
The green synthesis of silver-chitosan nanocomposite (AgCs) is a promising avenue in nanobiotechnology, offering eco-friendly production methods and multifunctional properties. This study elucidates the green synthesis of AgNp through a su…
View article: Genomic insights and Taguchi-based optimization of culture conditions for enhanced alkaline protease production in Streptomyces barkulensis RC1831
Genomic insights and Taguchi-based optimization of culture conditions for enhanced alkaline protease production in Streptomyces barkulensis RC1831 Open
This study presents a genome analysis identifying various alkaline protease genes and culture condition optimization to enhance the production of the enzyme in Streptomyces barkulensis RC1831. The analysis of genes using bioinformatics too…
View article: Salt-resistant Streptomyces consortia promote growth of rice (Oryza sativa var. Swarna) alleviating salinity and drought stress tolerance by enhancing photosynthesis, antioxidant function, and proline content
Salt-resistant Streptomyces consortia promote growth of rice (Oryza sativa var. Swarna) alleviating salinity and drought stress tolerance by enhancing photosynthesis, antioxidant function, and proline content Open
Salinity and drought are the major abiotic stresses that significantly affect growth and productivity, necessitating the development and exploration of technologies to enhance tolerance of the crop plants. This study explored the role of f…
View article: Unveiling the anticancer potential of L-Asparaginase (ASNase) from novel Streptomyces isolate HB2AG: Purification and characterization study
Unveiling the anticancer potential of L-Asparaginase (ASNase) from novel Streptomyces isolate HB2AG: Purification and characterization study Open
L-asparaginase (ASNase) obtained from microbial origins is a significant enzyme in the commercial sphere, crucial for the treatment of acute lymphoblastic leukemia. In the current investigation, we isolated ASNase through techniques involv…
View article: De novo assembly and comparative genome analysis for polyhydroxyalkanoates-producing Bacillus sp. BNPI-92 strain
De novo assembly and comparative genome analysis for polyhydroxyalkanoates-producing Bacillus sp. BNPI-92 strain Open
This newly obtained isolate was found to be new a strain based on comparative genomic analysis and it was also observed as a potential candidate for PHA biosynthesis.
View article: Partial purification and characterization of an extracellular Chitin Deacetylase from Streptomyces griseoinacarnatus RB7AG isolated from Chilika lake
Partial purification and characterization of an extracellular Chitin Deacetylase from Streptomyces griseoinacarnatus RB7AG isolated from Chilika lake Open
An extracellular thermo-alkali tolerant chitin deacetylase (CDA) was obtained from Streptomyces griseoincarnatus RB7AG, isolated from Chilika lake sediments. The purification of the enzyme was carried out by ammonium sulfate precipitation,…
View article: Polyhydroxyalkanoate Recovery From Newly Screened Bacillus Sp. LPPI-81 Using Various Methods of Extraction From Loktak Lake Sediment Sample
Polyhydroxyalkanoate Recovery From Newly Screened Bacillus Sp. LPPI-81 Using Various Methods of Extraction From Loktak Lake Sediment Sample Open
Nowadays the conventional plastic wastes are very challenging to environments and its production cost also creates an economic crisis due to petrochemical-based plastic. In order to solve this problem, the current studies were aimed at scr…
View article: How RAS mutations really work
How RAS mutations really work Open
Signal Transduction
Mutations in the small guanosine triphosphatase RAS occur in many human tumors and are thought to act by activating the mitogen-activated protein kinase (MAPK, also called ERK) signaling pathway. Gillies et al. used ima…
View article: Evaluation of a Potential Antibacterial Produced by Streptomyces Cinereoruber Sp Isolated from Chlika lake
Evaluation of a Potential Antibacterial Produced by Streptomyces Cinereoruber Sp Isolated from Chlika lake Open
Streptomyces, isolated from marine and estuarine habitat have been widely recognized as a potential source of antifungal, anti-tumour, anti-bacterial compounds. In the present study, the antimicrobial agent production potential of a Strept…
View article: Draft Genome Sequence of the Plant Growth-Promoting Rhizobacterium <i>Klebsiella</i> sp. Strain KBG6.2, Imparting Salt Tolerance to Rice
Draft Genome Sequence of the Plant Growth-Promoting Rhizobacterium <i>Klebsiella</i> sp. Strain KBG6.2, Imparting Salt Tolerance to Rice Open
Klebsiella sp. strain KBG6.2 is a potential salt-tolerant, plant growth-promoting rhizobacterium isolated from a rice field in Konark, Odisha, India. Here, we report the whole-genome sequencing of Klebsiella sp. strain KBG6.2, which has a …
View article: Dogs race through development
Dogs race through development Open
Aging
To get a better understanding of epigenetic changes that occur during development and aging, Wang et al. compared lifetime changes in the DNA methylomes of dogs and humans. Changes in methylation of cytosine-guanine dinucleotides in …
View article: miRNAs mediate mTORC1 effects
miRNAs mediate mTORC1 effects Open
Signal Transduction
Too much signaling by the mammalian target of rapamycin complex 1 (mTORC1) protein kinase complex is a bad thing in part because it enhances production of particular microRNAs (miRNAs). Mouse cells engineered to lack th…
View article: Application of Computer Assisted Bimolecular Interaction Modelling in Predictive Microbiology, Current State and Future Prospects
Application of Computer Assisted Bimolecular Interaction Modelling in Predictive Microbiology, Current State and Future Prospects Open
With the rapid evolution of Biotechnology and Green Technology, Microbial synthesis of commercially relevant biological compounds has been emerging for the past few decades. These economically valuable bio-compounds that have numerous appl…
View article: Network rewiring in cancer
Network rewiring in cancer Open
Signaling
Cancer-causing mutations are likely to modulate existing signaling networks rather than generate newly rewired networks. During tumor growth, tyrosine phosphorylation offers a candidate mechanism for transient alteration of physi…
View article: Loss of control in aging brains
Loss of control in aging brains Open
Aging
Aging is often accompanied by deterioration in learning and memory. Given that loss of learning capacity is not usually associated with massive cell death, subtler changes must be at work. To understand what is happening at the level…
View article: Receptor get-together for hematopoiesis
Receptor get-together for hematopoiesis Open
Signal Transduction
Wnt signaling is involved in many organismal processes. What is poorly understood in each pathway is which Wnt ligand requires which receptor. Blood-cell proliferation and specialization (hematopoiesis) requires specifi…
View article: Turning on a G protein receptor
Turning on a G protein receptor Open
Signal Transduction
The mammalian target of rapamycin complex 1 (mTORC1) protein kinase is activated at the lysosomal membrane and helps control autophagy and metabolism. It interacts with other proteins that act as sensors for stimuli lik…