Carolina Oi Lam Ung
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View article: Using unsupervised machine learning methods to cluster cardio-metabolic profile of the middle-aged and elderly Chinese with general and central obesity
Using unsupervised machine learning methods to cluster cardio-metabolic profile of the middle-aged and elderly Chinese with general and central obesity Open
This data-driven study identified a novel classification strategy to identify subtypes of the middle-aged and elderly Chinese with general obesity and central obesity and classify their adiposity and cardio-metabolic profiles. With clinica…
View article: Qualitative study of stakeholder perspectives on dementia policy implementation in Macao: progress, challenges and future directions
Qualitative study of stakeholder perspectives on dementia policy implementation in Macao: progress, challenges and future directions Open
Objectives To better inform dementia management, it is important to understand how individuals experience, interpret and respond to dementia policy in real life. This study aimed to explore key stakeholders’ perspectives on the critical de…
View article: Building Decay in Hong Kong: Assessing and Mapping Building Condition Index Using ChatGPT and Airborne Point Clouds
Building Decay in Hong Kong: Assessing and Mapping Building Condition Index Using ChatGPT and Airborne Point Clouds Open
Hong Kong faces critical challenges in the maintenance and redevelopment of aged buildings. Recently, advancements in multi-modal generative AI (GenAI) and high-definition urban geospatial data, such as point clouds, have offered new oppor…
View article: Advancing human-use experience for real-world evidence for the registration of traditional Chinese medicine products in China
Advancing human-use experience for real-world evidence for the registration of traditional Chinese medicine products in China Open
HUE can be advanced to generate RWE for the safety and effectiveness of TCM products, which provides potential support for registering new TCM products. Leveraging HUE for registration can shorten research and development period, reduce de…
View article: Implementation of Clinical Services for Adults with Obesity in Different Health Systems: A Scoping Review and Causal Loop Diagram
Implementation of Clinical Services for Adults with Obesity in Different Health Systems: A Scoping Review and Causal Loop Diagram Open
The medical needs of obesity have been underrecognized, though it has posed long-term and enormous challenges to global health. Correspondingly, clinical services for obesity are still uncommon and in their infancy across health systems. I…
View article: Long- and Short-Term Cost-Effectiveness of Once-Weekly Semaglutide versus Dulaglutide for the Treatment of Type 2 Diabetes in China: A Hypothetical Modeling Exercise
Long- and Short-Term Cost-Effectiveness of Once-Weekly Semaglutide versus Dulaglutide for the Treatment of Type 2 Diabetes in China: A Hypothetical Modeling Exercise Open
Compared to dulaglutide 1.5 mg, once-weekly semaglutide remains cost-effective for treating type 2 diabetes uncontrolled on metformin in China under the new negotiation price. However, limitations exist, including the reliance on SUSTAIN-7…
View article: Disparities in the access to immune checkpoint inhibitors approved in the United States, the European Union and mainland China: a serial cross-sectional study
Disparities in the access to immune checkpoint inhibitors approved in the United States, the European Union and mainland China: a serial cross-sectional study Open
Background Immune checkpoint inhibitors (ICIs) have revolutionised antitumour therapy. However, regional differences in ICI labels, including the impact of the review process and supporting trial evidence, remain unclear. Methods We conduc…
View article: Exploring the knowledge, attitude, and practice of community pharmacists regarding pediatric asthma management in Guangdong Province, China: a cross-sectional survey study
Exploring the knowledge, attitude, and practice of community pharmacists regarding pediatric asthma management in Guangdong Province, China: a cross-sectional survey study Open
Background Pediatric asthma is a common respiratory disease that significantly affects children's physical and mental health. This study aims to investigate community pharmacists' self-reported knowledge of asthma and explore their attitud…
View article: Factors associated with participation of breast cancer screening in female residents in China: a systematic review and meta-analysis
Factors associated with participation of breast cancer screening in female residents in China: a systematic review and meta-analysis Open
Background: Breast cancer (BC) is the most common cancer and the leading cause of cancer-related death in women worldwide. According to the global cancer observatory of International Agency for Research on Cancer, the new cases, prevalent …
View article: Using system dynamics modeling approach to strengthen health systems to combat cancer: a systematic literature review
Using system dynamics modeling approach to strengthen health systems to combat cancer: a systematic literature review Open
SDM in cancer control is underutilized, focusing mainly on early detection and treatment. Inconsistencies suggest a need for standardized SDM approaches. Future research should expand SDM's application and integrate it into cancer control …
View article: Effectiveness of COVID-19 Vaccination against Severe Symptoms and Death Among Geriatric Inpatients: A Retrospective Cohort Study in Macao
Effectiveness of COVID-19 Vaccination against Severe Symptoms and Death Among Geriatric Inpatients: A Retrospective Cohort Study in Macao Open
Monitoring the effectiveness of COVID-19 vaccination is critical for understanding if the vaccinated population, especially the elderly, is adequately protected from the emergence of new SARS-CoV-2 variants. This study aimed to investigate…
View article: Safety and efficacy of phosphodiesterase-5 (PDE-5) inhibitors in fetal growth restriction: a systematic literature review and meta-analysis
Safety and efficacy of phosphodiesterase-5 (PDE-5) inhibitors in fetal growth restriction: a systematic literature review and meta-analysis Open
Introduction: Fetal growth restriction (FGR) is associated with a higher risk of perinatal morbidity and mortality, as well as long-term health issues in newborns. Currently, there is no effective medicine for FGR. Phosphodiesterase-5 (PDE…
View article: Implementation of the Macao dementia policy: a scoping review for the way forward
Implementation of the Macao dementia policy: a scoping review for the way forward Open
Background The implementation of dementia policy is a complex process of translating policy goals to actions to address the changing needs of people living with dementia. Leveraging on others’ experiences would help policy decision-makers …
View article: Editorial: Childhood vaccination and COVID-19
Editorial: Childhood vaccination and COVID-19 Open
EDITORIAL article Front. Pediatr., 21 November 2023Sec. Pediatric Infectious Diseases Volume 11 - 2023 | https://doi.org/10.3389/fped.2023.1298691
View article: Digital Medical Information Services Delivered by Pharmaceutical Companies via WeChat: Qualitative Analytical Study
Digital Medical Information Services Delivered by Pharmaceutical Companies via WeChat: Qualitative Analytical Study Open
Background Social media has become one of the primary information sources for medical professionals and patients. Pharmaceutical companies are committed to using various social media platforms to provide stakeholders with digital medical i…
View article: Pharmacoeconomic evaluation of anti-obesity drugs for chronic weight management: a systematic review of literature
Pharmacoeconomic evaluation of anti-obesity drugs for chronic weight management: a systematic review of literature Open
Introduction Pharmacological therapy is recommended as a second-line alternative to reverse obesity. Currently, five anti-obesity drugs (AODs) have been approved by the U.S. Food and Drug Administration (FDA) for chronic weight management.…
View article: Is there a role for traditional and complementary medicines in managing chronic fatigue? a systematic review of randomized controlled trials
Is there a role for traditional and complementary medicines in managing chronic fatigue? a systematic review of randomized controlled trials Open
Introduction: Chronic fatigue syndrome (CFS) is an increasingly common condition that is challenging to treat due to unclear etiology and a lack of consensus on clinical diagnosis and treatment guidance. Many affected people resorted to us…
View article: Comparative analysis of disease modelling for health economic evaluations of systemic therapies in advanced hepatocellular carcinoma
Comparative analysis of disease modelling for health economic evaluations of systemic therapies in advanced hepatocellular carcinoma Open
Background The objective of this study was to systematically analyse methodological and structural assumptions utilised in model-based health economic evaluations of systemic advanced hepatocellular carcinoma (HCC) therapies, discuss the e…
View article: Benchmarking Drug Regulatory Systems for Capacity Building: An Integrative Review of Tools, Practice and Recommendations
Benchmarking Drug Regulatory Systems for Capacity Building: An Integrative Review of Tools, Practice and Recommendations Open
Background: Benchmarking has been increasingly used on drug regulatory systems to achieve sustainable pharmaceutical system strengthening. This study aimed to identify the scope, tools and benefits of benchmarking regulatory capacities and…