Explanipedia

Characterizing the Relationship Between Intervention Delivery and Outcomes Within Part C Community Settings Open

Katherine Pickard, Scott Gillespie, Aubyn C. Stahmer, Jennifer S. Singh, Lawrence David Scahill · 2025

Routine Early Intervention services are an ideal context to evaluate parent-mediated intervention (PMI) delivery. While effectiveness research suggests that receiving manualized PMIs positively affects caregivers’ learning and use of inter…

Clinical Correlates of Insomnia Symptoms in Young Children with Autism Spectrum Disorder Open

Megan L Wenzell, Stormi L. Pulver, Lawrence David Scahill, Tanya Davidson, Sandhya Rajagopal , et al. · 2025

Evaluating Intervention Fidelity and Adaptation Within Context: A Mixed-Methods Study of Implementation Practice Within Public Early Intervention Systems Open

Katherine Pickard, Nailah Islam, Aubyn C. Stahmer, R. Christopher Sheldrick, Scott Gillespie , et al. · 2025

Background The science of intervention adaptation is rapidly expanding, yet there has been limited research evaluating how context affects intervention fidelity and adaptation. The current study sought to address this gap by closely charac…

Development of a novel parent‐report measure of food allergy impact Open

Kaitlin B. Proctor, Hayley Estrem, Ji Soo Park, Megan L Wenzell, M. Ravindran , et al. · 2024

Aim The aim of this study was to develop an outcome measure for caregivers of children with food allergy. Methods A community‐informed measure development process was utilised to generate a novel parent‐reported outcome tool for caregivers…

Correction: A Survey of Community Providers on Feeding Problems in Autism Spectrum Disorder Open

T. Lindsey Burrell, William G. Sharp, Scott Gillespie, Katherine Pickard, Susan Brasher , et al. · 2023

Assessing the Family-Level Impact of Pediatric Food Allergy: Development of the PEACH Tool Open

Kaitlin B. Proctor, Hayley Estrem, Jinhee Park, Mayuran Ravindran, Megan L. Alder , et al. · 2023

Childhood Predictors of Long-Term Tic Severity and Tic Impairment in Tourette’s Disorder Open

Emily J. Ricketts, Douglas W. Woods, Flint M. Espil, Joseph McGuire, Jordan T. Stiede , et al. · 2022

Tics peak in late childhood and decline during adolescence. Yet, for some with Tourette's disorder, tics persist into adulthood. We evaluated childhood predictors of adult tic severity and tic impairment, and change over time. Eighty adole…

Citalopram Did Not Significantly Improve Anxiety in Children with Autism Spectrum Disorder Undergoing Treatment for Core Symptoms: Secondary Analysis of a Trial to Reduce Repetitive Behaviors Open

Emily Simonoff, Florence D. Mowlem, Oliver P. Pearson, Evdokia Anagnostou, Craig L. Donnelly , et al. · 2022

Objective: Anxiety disorders are among the most common co-occurring conditions in autism spectrum disorder (ASD). Despite their prevalence and impact, there are no randomized controlled trials (RCTs) aimed at evaluating the e…

Direct observation in a large-scale randomized trial of parent training in children with autism spectrum disorder and disruptive behavior Open

Naomi B. Swiezy, Tristam Smith, Cindy R. Johnson, Karen Bearss, Luc Lecavalier , et al. · 2021

Using the big data approach to clarify the structure of restricted and repetitive behaviors across the most commonly used autism spectrum disorder measures Open

Mirko Uljarević, Booil Jo, Thomas Frazier, Lawrence David Scahill, Eric A. Youngstrom , et al. · 2021

Editors’ Note and Special Communication: Research Priorities in Child and Adolescent Mental Health Emerging From the COVID-19 Pandemic Open

Douglas K. Novins, Joel Stoddard, Robert R. Althoff, Alice Charach, Samuele Cortese , et al. · 2021

Homework adherence predicts therapeutic improvement from behavior therapy in Tourette's disorder Open

Joey Ka-Yee Essoe, Emily J. Ricketts, Kesley A. Ramsey, John Piacentini, Douglas W. Woods , et al. · 2021

Defining tic severity and tic impairment in Tourette Disorder Open

Joseph McGuire, John Piacentini, Eric A. Storch, Emily J. Ricketts, Douglas W. Woods , et al. · 2020

Predictors of Caregiver Strain for Parents of Children with Autism Spectrum Disorder Open

Jessica Bradshaw, Scott Gillespie, Courtney McCracken, Bryan H. King, James T. McCracken , et al. · 2020

Exploring the Manifestations of Anxiety in Children with Autism Spectrum Disorders Open

Victoria Hallett, Luc Lecavalier, Denis G. Sukhodolsky, Noreen Cipriano, Michael G. Aman , et al. · 2020

This study explores the manifestation and measurement of anxiety symptoms in 415 children with ASDs on a 20-item, parent-rated, DSM-IV referenced anxiety scale. In both high and low-functioning children (IQ above vs below 70), commonly end…

Baseline Factors Predicting Placebo Response to Treatment in Children and Adolescents With Autism Spectrum Disorders: A Multisite Randomized Clinical Trial Open

Bryan H. King, Kimberly A. Dukes, Craig L. Donnelly, Linmarie Sikich, James T. McCracken , et al. · 2020

The finding of factors that differentially predict the likelihood of response to placebo over that of an active drug could have a significant impact on study design in this population.

Lack of Efficacy of Citalopram in Children With Autism Spectrum Disorders and High Levels of Repetitive Behavior: Citalopram Ineffective in Children With Autism Open

Bryan H. King, Eric Hollander, Linmarie Sikich, James T. McCracken, Lawrence David Scahill , et al. · 2020

Selective serotonin reuptake inhibitors are widely prescribed for children with autism spectrum disorders.

Factors associated with study protocol adherence and bio banking participation in reproductive medicine clinical trials and their relationship to live birth Open

Lawrence Engmann, Fangbai Sun, Richard S. Legro, Michael P. Diamond, Heping Zhang , et al. · 2020

STUDY QUESTION What demographic and baseline characteristics are predictive of adherence to reproductive medicine clinical trial protocols, live birth or participation in genetic studies? SUMMARY ANSWER Race, BMI and lower income are assoc…

Treatment use among children with Tourette syndrome living in the United States, 2014 Open

Sara Beth Wolicki, Rebecca H. Bitsko, Joseph R. Holbrook, Melissa L. Danielson, Benjamin Zablotsky , et al. · 2020

Treatment of Folate Metabolism Abnormalities in Autism Spectrum Disorder Open

Richard E. Frye, Daniel A. Rossignol, Lawrence David Scahill, Christopher J. McDougle, Harris S. Huberman , et al. · 2020

Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder that currently has no approved medical therapy to address core symptoms or underling pathophysiological processes. Several compounds are under development that a…

Reliability and validity of the Pediatric Anxiety Rating Scale modified for autism spectrum disorder Open

Brenna B. Maddox, Luc Lecavalier, Judith S. Miller, Jill Pritchett, Jill A. Hollway , et al. · 2020

Anxiety often co-occurs with autism spectrum disorder, yet there are few valid and reliable instruments for measuring anxiety in youth with autism spectrum disorder. This article describes the modification of the Pediatric Anxiety Rating S…

Obsessive-Compulsive and Related Disorders in Autism Spectrum Disorder Open

Lawrence David Scahill, Andrea Nichole Evans · 2020

Obsessive-compulsive and related disorders (OCRDs) are a group of diagnoses that center on compulsive behaviors and/or obsessive thoughts. They include obsessive-compulsive disorder (OCD), body dysmorphic disorder (BDD), hoarding disorder,…

The role of emotion regulation and core autism symptoms in the experience of anxiety in autism Open

Caitlin M. Conner, Susan W. White, Lawrence David Scahill, Carla A. Mazefsky · 2020

Youth with autism spectrum disorder are at elevated risk for impaired emotion regulation and clinically impairing anxiety. A prior developmental framework posited that impaired emotion regulation leads to co-occurring psychiatric condition…

Maladaptive Aggression: With a Focus on Impulsive Aggression in Children and Adolescents Open

Daniel F. Connor, Jeffrey H. Newcorn, Keith E. Saylor, Birgit H. Amann, Lawrence David Scahill , et al. · 2019

Objective: Aggressive behavior is among the most common reasons for referral to psychiatric clinics and confers significant burden on individuals. Aggression remains poorly defined; there is currently no consensus on the best…

Effect of behavior therapy for Tourette's disorder on psychiatric symptoms and functioning in adults Open

Joseph McGuire, Emily J. Ricketts, Lawrence David Scahill, Sabine Wilhelm, Douglas W. Woods , et al. · 2019

Background Although behavior therapy reduces tic severity, it is unknown whether it improves co-occurring psychiatric symptoms and functional outcomes for adults with Tourette's disorder (TD). This information is essential for effective tr…

Anxiety in 3- to 7-year-old children with autism spectrum disorder seeking treatment for disruptive behavior Open

Denis G. Sukhodolsky, Luc Lecavalier, Cynthia R. Johnson, Tristram Smith, Naomi B. Swiezy , et al. · 2019

Anxiety is a common and impairing problem in children with autism spectrum disorder, but little is known about it in preschool children with autism spectrum disorder. This article reports on the characteristics of anxiety symptoms in young…

The Autism Managing Eating Aversions and Limited Variety Plan vs Parent Education: A Randomized Clinical Trial Open

William G. Sharp, T. Lindsey Burrell, Rashelle C. Berry, Kathryn H. Stubbs, Courtney McCracken , et al. · 2019

An exploration of concomitant psychiatric disorders in children with autism spectrum disorder Open

Luc Lecavalier, Courtney McCracken, Michael G. Aman, Christopher J. McDougle, James T. McCracken , et al. · 2018

In this well-characterized sample of treatment-seeking children with ASD, rates of concomitant psychiatric disorders were high and the presence of two or more co-occurring disorders was common. Findings highlight the importance of improvin…

Major depression, antidepressant use, and male and female fertility Open

Emily Evans-Hoeker, Esther Eisenberg, Michael P. Diamond, Richard S. Legro, Ruben Alvero , et al. · 2018

A multicenter examination and strategic revisions of the Yale Global Tic Severity Scale Open

Joseph McGuire, John Piacentini, Eric A. Storch, Tanya K. Murphy, Emily J. Ricketts , et al. · 2018

The YGTSS exhibits good internal consistency across children and adults. The parallel findings across Motor and Phonic Frequency, Complexity, and Interference dimensions prompted minor revisions to the anchor point description to promote u…

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