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View article: Novel proteomics biomarkers of recurrent pregnancy loss reflect the dysregulation of immune interactions at the maternal-fetal interface
Novel proteomics biomarkers of recurrent pregnancy loss reflect the dysregulation of immune interactions at the maternal-fetal interface Open
Introduction Miscarriages affect 50-70% of all gestations and 15-20% of clinically recognized pregnancies. Recurrent pregnancy loss (RPL) occurs in 1-5% of clinical pregnancies and has an enormous demographic impact. However, the etiologie…
View article: Understanding leptin’s influence on calf development: A review of metabolic and reproductive mechanisms
Understanding leptin’s influence on calf development: A review of metabolic and reproductive mechanisms Open
Leptin, a hormone primarily produced by adipose tissue, regulates the energy balance, metabolism, and reproductive functions. This review explores leptin's role in calf development from embryogenesis to puberty. Leptin expression is strong…
View article: Climate-Smart Agricultural Practices—Strategies to Conserve and Increase Soil Carbon in Hungary
Climate-Smart Agricultural Practices—Strategies to Conserve and Increase Soil Carbon in Hungary Open
This review summarizes the role of soil in climate change mitigation and highlights the potential of agricultural practices to support this effort. It provides an overview of methods that enhance soil carbon sequestration and reduce carbon…
View article: Stream water quality variation as a function of physical environmental conditions in an agriculturally dominated catchment
Stream water quality variation as a function of physical environmental conditions in an agriculturally dominated catchment Open
The aim of the present study was to investigate stream turbidity and water chemical parameters under varying environmental conditions. We analyzed a three-year-long (2021-2023) daily and bi-weekly dataset collected at six points (P1-P6) al…
View article: Are There Potential Benefits From Using Microbial Products to Control Ammonia and Greenhouse Gases Released From Pig Slurry?
Are There Potential Benefits From Using Microbial Products to Control Ammonia and Greenhouse Gases Released From Pig Slurry? Open
Livestock farming and its slurry management represent a significant contributor to global anthropogenic ammonia (NH 3 ) and greenhouse gas (GHG) emissions, resulting in negative impacts on the environment. The aim of this study was to eval…
View article: Decreased Expression of Placental Proteins in Recurrent Pregnancy Loss: Functional Relevance and Diagnostic Value
Decreased Expression of Placental Proteins in Recurrent Pregnancy Loss: Functional Relevance and Diagnostic Value Open
Miscarriages affect 50–70% of all conceptions and 15–20% of clinically recognized pregnancies. Recurrent pregnancy loss (RPL, ≥2 miscarriages) affects 1–5% of recognized pregnancies. Nevertheless, our knowledge about the etiologies and pat…
View article: Developing a method to estimate the ammonia loss from fertilized cropland and the part of soil emission recaptured by the canopy, applying field scale bidirectional models and flux measurements
Developing a method to estimate the ammonia loss from fertilized cropland and the part of soil emission recaptured by the canopy, applying field scale bidirectional models and flux measurements Open
In parameterization of the bidirectional ammonia exchange models over vegetated surfaces there are some crucial parameters: the stomatal, the soil, and the cuticular compensation point concentrations as the function of [NH4+]/[H+] ratio in…
View article: Position-dependent sequence motif preferences of SpCas9 are largely determined by scaffold-complementary spacer motifs
Position-dependent sequence motif preferences of SpCas9 are largely determined by scaffold-complementary spacer motifs Open
Streptococcus pyogenes Cas9 (SpCas9) nuclease exhibits considerable position-dependent sequence preferences. The reason behind these preferences is not well understood and is difficult to rationalise, since the protein establishes interact…
View article: TUdi meta-database of long-term monitored farms and experiments to support soil degradation detection
TUdi meta-database of long-term monitored farms and experiments to support soil degradation detection Open
Within the TUdi project a comprehensive list of long-term monitored farms and experiments have been created in 2022, including basic data on the agricultural system, farm typology, soil and climate,  and soil restoring strategies impl…
View article: Application of a bi-directional ammonia exchange model for optimization of input parameters at a fertilized crop system; validation by flux measurements
Application of a bi-directional ammonia exchange model for optimization of input parameters at a fertilized crop system; validation by flux measurements Open
In parameterization of the bi-directional ammonia exchange models over vegetated surfaces there are three most crucial parameters: (1) the stomatal (χs) and (2) the soil (χg) compensation point concentrations as the function of &…
View article: Placental galectins regulate innate and adaptive immune responses in pregnancy
Placental galectins regulate innate and adaptive immune responses in pregnancy Open
Introduction Galectins are master regulators of maternal immune responses and placentation in pregnancy. Galectin-13 (gal-13) and galectin-14 (gal-14) are expressed solely by the placenta and contribute to maternal-fetal immune tolerance b…
View article: Influence of Pig Slurry Application Techniques on Soil CO2, N2O, and NH3 Emissions
Influence of Pig Slurry Application Techniques on Soil CO2, N2O, and NH3 Emissions Open
Greenhouse gas (GHG) emissions from agricultural soils can accelerate climate change, therefore, different soil fertilization techniques should be assessed before application to reduce GHG emissions. Pig slurry applications can greatly inf…
View article: Target-matched increased fidelity SpCas9 variants can edit any target without genome-wide off-target effects
Target-matched increased fidelity SpCas9 variants can edit any target without genome-wide off-target effects Open
Streptococcus pyogenes Cas9 (SpCas9) has been employed as a genome engineering tool with a promising potential within therapeutics. However, its off- target effects pose a major limitation for applications requiring high specificity. Appro…
View article: Proteomic Changes of Osteoclast Differentiation in Rheumatoid and Psoriatic Arthritis Reveal Functional Differences
Proteomic Changes of Osteoclast Differentiation in Rheumatoid and Psoriatic Arthritis Reveal Functional Differences Open
Background Osteoclasts play a crucial role in the maintenance, repair, and remodeling of bones of the adult vertebral skeleton due to their bone resorption capability. Rheumatoid arthritis (RA) and psoriatic arthritis (PsA) are associated …
View article: Deep-SAGA: a deep-learning-based system for automatic gaze annotation from eye-tracking data
Deep-SAGA: a deep-learning-based system for automatic gaze annotation from eye-tracking data Open
With continued advancements in portable eye-tracker technology liberating experimenters from the restraints of artificial laboratory designs, research can now collect gaze data from real-world, natural navigation. However, the field lacks …
View article: Effect of different tillage methods on soil N2O emission in an arable field 
Effect of different tillage methods on soil N2O emission in an arable field  Open
<p>In this study we investigated the effect of mouldboard ploughing (MP), shallow cultivation (SC) and no-tillage (NT) methods on N<sub>2</sub>O emission of a Central European long-term field experiment. We measured N<…
View article: Climate Change Alters Soil Water Dynamics under Different Land Use Types
Climate Change Alters Soil Water Dynamics under Different Land Use Types Open
Land use and management affect soil hydrological processes, and the impacts can be further enhanced and accelerated due to climate change. In this study, we analyzed the possible long-term effects of different land use types on soil hydrol…
View article: Soil-related developments of the Biome-BGCMuSo v6.2 terrestrial ecosystem model
Soil-related developments of the Biome-BGCMuSo v6.2 terrestrial ecosystem model Open
Terrestrial biogeochemical models are essential tools to quantify climate–carbon cycle feedback and plant–soil relations from local to global scale. In this study, a theoretical basis is provided for the latest version of the Biome-BGCMuSo…
View article: Author Correction: A morphological analysis of activity-dependent myelination and myelin injury in transitional oligodendrocytes
Author Correction: A morphological analysis of activity-dependent myelination and myelin injury in transitional oligodendrocytes Open
5, where data and statistical results shown in panels C and D were based on a previous analysis which did not reflect the aggregation of image data points to individual brain slices.
View article: Changes in the Soil–Plant–Water System Due to Biochar Amendment
Changes in the Soil–Plant–Water System Due to Biochar Amendment Open
The aim of this study was to do a complex examination of the soil–plant–water system and soil greenhouse gas emissions when biochar is applied to soil planted with sweet corn (Zea mays L. var. saccharata). The study covers two consecutive …
View article: Influence of Post-Translational Modifications on Protein Identification in Database Searches
Influence of Post-Translational Modifications on Protein Identification in Database Searches Open
Comprehensive analysis of post-translation modifications (PTMs) is an important mission of proteomics. However, the consideration of PTMs increases the search space and may therefore impair the efficiency of protein identification. Using t…
View article: Comparison of soil CO2 emissions from three different tillage methods on chernozem soil
Comparison of soil CO2 emissions from three different tillage methods on chernozem soil Open
<p>Tillage practices influence soil CO<sub>2</sub> emissions, hence many research investigate the long-term effects of conservation and conventional tillage methods e.g. ploughing and no-tillage on soil greenhouse gas emi…
View article: Spatial variability of soil water content and soil chemistry affect grapevine growth in degraded slopes
Spatial variability of soil water content and soil chemistry affect grapevine growth in degraded slopes Open
<p>Three slopes with grapevines were investigated to see changes in the soil-plant-water system over vegetation growth. The slopes have the following parameters: 1) young grapevine plants with tilled soil (YR), 2) older grapevines wi…
View article: A method for characterizing Cas9 variants via a one-million target sequence library of self-targeting sgRNAs
A method for characterizing Cas9 variants via a one-million target sequence library of self-targeting sgRNAs Open
Detailed target-selectivity information and experiment-based efficacy prediction tools are primarily available for Streptococcus pyogenes Cas9 (SpCas9). One obstacle to develop such tools is the rarity of accurate data. Here, we report a m…