Renata Eloah de Lucena Ferretti‐Rebustini
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View article: Repercussions faced by health professionals who have experienced the phenomenon of the second victims due to incidents related to patient safety: A scoping review protocol
Repercussions faced by health professionals who have experienced the phenomenon of the second victims due to incidents related to patient safety: A scoping review protocol Open
Introduction: Patient safety is a relevant, timely and globally significant topic. In hospital settings, despite ongoing discussions and advances in patient safety, adverse events continue to occur, impacting not only patients but also hea…
View article: Promoting and strengthening the principles of Diversity, Equity, Inclusion, and Accessibility in Geriatrics, Gerontology and Aging
Promoting and strengthening the principles of Diversity, Equity, Inclusion, and Accessibility in Geriatrics, Gerontology and Aging Open
None.
View article: Ageism directed at older nurses in the workplace: a scoping review protocol
Ageism directed at older nurses in the workplace: a scoping review protocol Open
Introduction In the context of global population ageing, there is a continuous and significant increase in the average age of nursing professionals. However, evidence indicates that age bias may hinder older workers’ access to the necessar…
View article: Sociodemographic and clinical profile from the Brazilian very old 90+ study (BRAVO-90+)
Sociodemographic and clinical profile from the Brazilian very old 90+ study (BRAVO-90+) Open
Background Cognitive impairment and disability are frequent among the oldest-old population, particularly in low- and middle-income countries (LMIC), where this population is rapidly increasing. However, studies on people aged 90 or older …
View article: Influence of neurological severity and degree of dependence of patients after stroke on nursing workload: a retrospective cohort
Influence of neurological severity and degree of dependence of patients after stroke on nursing workload: a retrospective cohort Open
Objective: To verify the influence of neurological severity and the degree of dependence of patients after stroke on the nursing workload required during hospitalization in the Intensive Care Unit (ICU). Method: Retrospective cohort of pos…
View article: The prefrontal cortex of homozygous ε3 APOE carriers with local African ancestry has fewer transcripts compared to individuals with local European ancestry
The prefrontal cortex of homozygous ε3 APOE carriers with local African ancestry has fewer transcripts compared to individuals with local European ancestry Open
Background he APOE gene has been identified as a major risk factor for late‐onset Alzheimer’s disease (AD) and has three most common alleles: ε2, ε3, and ε4. The presence of the ε4 allele confers a dose‐dependent increased risk for the dis…
View article: Pathways underlying selective vulnerability to Alzheimer’s disease in aminergic brainstem nuclei
Pathways underlying selective vulnerability to Alzheimer’s disease in aminergic brainstem nuclei Open
Background The Neuromodulatory Subcortical System (NSS) consists of nuclei exhibiting early vulnerability to tauopathies, including Alzheimer’s Disease (AD). Within the NSS, there is a spectrum of vulnerability that becomes apparent in the…
View article: Effects of Curcumin on Treatment Outcome in Patients with Cancer Diagnosis
Effects of Curcumin on Treatment Outcome in Patients with Cancer Diagnosis Open
Introduction: Treatment options for palliative care in patients with cancer aim to improve quality of life, and, in this context, alternative, complementary treatments are under study to reduce treatment side effects and increase tradition…
View article: Assessment of intrinsic capacity in the Brazilian older population and the psychometric properties of the WHO/ICOPE screening tool: a multicenter cohort study protocol
Assessment of intrinsic capacity in the Brazilian older population and the psychometric properties of the WHO/ICOPE screening tool: a multicenter cohort study protocol Open
Introduction: The World Health Organization (WHO) has proposed to monitor intrinsic capacity (IC) in the older population as a public health strategy through the Integrated Care for Older People (ICOPE) program. Although the program has be…
View article: The ICOPE-WHO and the IVCF-20: a critical view of the Handbook for Multidimensional Geriatric Assessment in Primary Care
The ICOPE-WHO and the IVCF-20: a critical view of the Handbook for Multidimensional Geriatric Assessment in Primary Care Open
Rapid population aging is driving initiatives aimed at optimizing the health of older populations worldwide. In Brazil, the National Council of State Secretaries of Health (CONASS) recently published the Handbook for Multidimensional Geria…
View article: Quantification of encephalic transcripts of the APOE allele specific gene of European and African ancestry
Quantification of encephalic transcripts of the APOE allele specific gene of European and African ancestry Open
Background The APOE gene is identified as a major risk factor for late onset Alzheimer’s disease and has three alleles, ε2, ε3 and ε4, related to two non‐synonymous substitutions. The presence of the ε4 allele confers an increased risk for…
View article: Pathways to selective vulnerability in neuromodulatory subcortical structures during the early pathogenic stages of Alzheimer’s disease
Pathways to selective vulnerability in neuromodulatory subcortical structures during the early pathogenic stages of Alzheimer’s disease Open
Background The two main catecholaminergic members of the isodendritic core nuclei are the substantia nigra (SN) and the locus coeruleus (LC). Despite cytoarchitectural and neurochemical similarities between the two nuclei, the LC is signif…
View article: Chronic traumatic encephalopathy pathology in a large population‐based study.
Chronic traumatic encephalopathy pathology in a large population‐based study. Open
Background Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disease predominantly found in former athletes and associated with repetitive brain injury (TBI). Despite the increased number of studies, several questio…
View article: Tau conformational changes in aging‐related tau astrogliopathy.
Tau conformational changes in aging‐related tau astrogliopathy. Open
Background The presence of aging‐related tau astrogliopathy (ARTAG) is highly frequent, but poorly characterized in aging brain and neurodegeneration. Over the abnormal tau accumulation processes, tau protein undergoes pathological modific…
View article: The influence of age and sex on the absolute cell numbers of the human brain cerebral cortex
The influence of age and sex on the absolute cell numbers of the human brain cerebral cortex Open
The human cerebral cortex is one of the most evolved regions of the brain, responsible for most higher-order neural functions. Since nerve cells (together with synapses) are the processing units underlying cortical physiology and morpholog…
View article: Elaboration and validation of the Brazilian Scale of Perception about Euthanasia
Elaboration and validation of the Brazilian Scale of Perception about Euthanasia Open
This research elaborated an instrument to identify nurses’ perception on euthanasia and test its content validity, response process, internal structure and reliability evidences. A psychometric study was conducted through evaluation by a c…
View article: Content validity evidence of the Brazilian version of the Cognitive Symptom Checklist-Work-21
Content validity evidence of the Brazilian version of the Cognitive Symptom Checklist-Work-21 Open
Objective: to cross-culturally adapt and assess the content validity evidence of the Cognitive Symptom Checklist-Work-21 for the Brazilian context. Method: a psychometric study of cross-cultural adaptation, covering the stages of translati…
View article: Project ICOPE Brazil: a study on the intrinsic capacity of Brazilian older adults and accuracy of the screening tool proposed by the World Health Organization
Project ICOPE Brazil: a study on the intrinsic capacity of Brazilian older adults and accuracy of the screening tool proposed by the World Health Organization Open
None.
View article: Nursing Workload and care required by older adults in intensive care
Nursing Workload and care required by older adults in intensive care Open
Objective To analyze the workload and nursing care requirements of elderly people admitted to the intensive care unit (ICU) compared to adults. Method Cross-sectional study carried out in two ICUs of two hospitals (public and private) in t…
View article: Elaboration and validation of the Brazilian Scale of Perception about Euthanasia
Elaboration and validation of the Brazilian Scale of Perception about Euthanasia Open
This research elaborated an instrument to identify nurses’ perception on euthanasia and test its content validity, response process, internal structure and reliability evidences. A psychometric study was conducted through evaluation by a c…
View article: Neuropathological correlates of neuropsychiatric symptoms in dementia
Neuropathological correlates of neuropsychiatric symptoms in dementia Open
Introduction Neuropsychiatric symptoms (NPS) are common in Lewy body disease (LBD), but their etiology is poorly understood. Methods In a population‐based post mortem study neuropathological data was collected for Lewy body (LB) neuropatho…
View article: Global and local ancestry modulate APOE association with Alzheimer’s neuropathology and cognitive outcomes in an admixed sample
Global and local ancestry modulate APOE association with Alzheimer’s neuropathology and cognitive outcomes in an admixed sample Open
Dementia is more prevalent in Blacks than in Whites, likely due to a combination of environmental and biological factors. Paradoxically, clinical studies suggest an attenuation of APOE ε4 risk of dementia in African ancestry (AFR), but a d…
View article: Hyperlactatemia and worse outcomes in patients undergoing cardiac surgery: a retrospective cohort study
Hyperlactatemia and worse outcomes in patients undergoing cardiac surgery: a retrospective cohort study Open
Objective: Identify the factors, complications, and outcomes associated with hyperlactatemia in patients undergoing cardiac surgery. Methods: A retrospective cohort study including patients with hyperlactatemia admitted to the surgical int…
View article: Hyperlactatemia associated with mortality in patients undergoing cardiac surgery: a retrospective cohort study
Hyperlactatemia associated with mortality in patients undergoing cardiac surgery: a retrospective cohort study Open
Hyperlactatemia and worse outcomes in patients undergoing cardiac surgery: a retrospective cohort studyHiperlactatemia e piores desfechos em pacientes submetidos à cirurgia cardíaca: um estudo de coorte retrospective Hiperlactatemia y peor…
View article: Breastfeeding Practices and Childhood Nutritional Outcomes in Rural India
Breastfeeding Practices and Childhood Nutritional Outcomes in Rural India Open
Objective: To investigate the factors in relation to childhood nutritional outcomes and breastfeeding practices in rural and urban India.
View article: Global and local ancestry modulate<i>APOE</i>association with Alzheimer’s neuropathology and cognitive outcomes in an admixed sample
Global and local ancestry modulate<i>APOE</i>association with Alzheimer’s neuropathology and cognitive outcomes in an admixed sample Open
Dementia is more prevalent in Blacks than in Whites, likely due to a combination of environmental and biological factors. Paradoxically, clinical studies suggest an attenuation of APOE ε4 risk of dementia in African ancestry (AFR), but lac…
View article: The role of assessment in competence-based gerontological advanced practice nursing
The role of assessment in competence-based gerontological advanced practice nursing Open
Population aging challenges healthcare systems, requiring gerontological advanced practice nurses (GAPN) to address specific and complex care requirements of older adults. GAPN implement evidence-based practices directed to patients and fa…
View article: Brain areas involved with obsessive-compulsive disorder present different DNA methylation modulation
Brain areas involved with obsessive-compulsive disorder present different DNA methylation modulation Open
Background Obsessive-compulsive disorder (OCD) is characterized by intrusive thoughts and repetitive actions, that presents the involvement of the cortico-striatal areas. The contribution of environmental risk factors to OCD development su…