L. Groşeanu
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View article: Lack of Significant Associations Between Hematological Parameters, Salivary Gland Histopathology and Fatigue in Sjögren’s Disease
Lack of Significant Associations Between Hematological Parameters, Salivary Gland Histopathology and Fatigue in Sjögren’s Disease Open
Fatigue is a common and disabling symptom in Sjögren’s disease (SjD), yet its links with hematologic parameters and salivary gland histopathology are not well established. This study aimed to investigate associations between complete blood…
View article: Increased Intestinal Permeability and Articular Involvement in Systemic Lupus Erythematosus Patients—A Mutually Exclusive Relationship?
Increased Intestinal Permeability and Articular Involvement in Systemic Lupus Erythematosus Patients—A Mutually Exclusive Relationship? Open
Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disorder characterized by complex interactions between the innate and adaptive immune systems, being potentially associated with an enhanced intestinal permeability. Zonulin …
View article: Systemic Sclerosis-Associated ILD: Insights and Limitations of ScleroID
Systemic Sclerosis-Associated ILD: Insights and Limitations of ScleroID Open
Background: Pulmonary involvement in systemic sclerosis (SSc) is typically assessed using pulmonary function tests (PFTs), high-resolution CT (HRCT), and composite indices. Patient-reported outcomes (PRO), including ScleroID, provide insig…
View article: Radiofrequency Echographic Multi Spectrometry—A Novel Tool in the Diagnosis of Osteoporosis and Prediction of Fragility Fractures: A Systematic Review
Radiofrequency Echographic Multi Spectrometry—A Novel Tool in the Diagnosis of Osteoporosis and Prediction of Fragility Fractures: A Systematic Review Open
Background/Objectives: Given the significant economic and social burden of osteoporosis, there is growing interest in developing an efficient alternative to the traditional dual-energy X-ray absorptiometry (DXA). Radiofrequency Echographic…
View article: Association between Left Atrial Function and Survival in Systemic Sclerosis
Association between Left Atrial Function and Survival in Systemic Sclerosis Open
Systemic sclerosis (SSc) is a multisystemic autoimmune disorder in which cardiac involvement is frequent and portends negative prognosis. Left ventricular (LV) diastolic dysfunction is one of the most common cardiac alterations in these pa…
View article: A Systematic Review of the Key Predictors of Progression and Mortality of Rheumatoid Arthritis-Associated Interstitial Lung Disease
A Systematic Review of the Key Predictors of Progression and Mortality of Rheumatoid Arthritis-Associated Interstitial Lung Disease Open
Background: Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) is an important extra-articular manifestation of rheumatoid arthritis (RA). Identifying patients at risk of progression and death is crucial for improving RA-IL…
View article: The Constellation of Risk Factors and Paraneoplastic Syndromes in Cholangiocarcinoma: Integrating the Endocrine Panel Amid Tumour-Related Biology (A Narrative Review)
The Constellation of Risk Factors and Paraneoplastic Syndromes in Cholangiocarcinoma: Integrating the Endocrine Panel Amid Tumour-Related Biology (A Narrative Review) Open
Cholangiocarcinomas (CCAs), a heterogeneous group of challenging malignant tumours which originate from the biliary epithelium, are associated with an alarming increasing incidence during recent decades that varies between different region…
View article: Association between left atrial function and outcome in systemic sclerosis
Association between left atrial function and outcome in systemic sclerosis Open
Purpose: Systemic sclerosis (SSc) is a multisystemic autoimmune disorder in which cardiac involvement is frequent and portends negative prognosis. Left ventricular (LV) diastolic dysfunction is one of the most common cardiac alterations in…
View article: Calcinosis in Rheumatic Disease Is Still an Unmet Need: A Retrospective Single-Center Study
Calcinosis in Rheumatic Disease Is Still an Unmet Need: A Retrospective Single-Center Study Open
Patients with immune-mediated rheumatic disease-related calcinosis comprise a subgroup at risk of encountering a more severe clinical outcome. Early assessment is pivotal for preventing overall disease progression, as calcinosis is commonl…
View article: The Physical and Psychosocial Impact of Fatigue among Patients with Sjogren’s Syndrome: A Systematic Review
The Physical and Psychosocial Impact of Fatigue among Patients with Sjogren’s Syndrome: A Systematic Review Open
Background: Primary Sjögren’s syndrome (pSS) is a complex autoimmune disorder characterized by organ-specific symptoms in the salivary and lacrimal glands, as well as systemic manifestations. Fatigue, a prominent aspect, significantly infl…
View article: Interstitial lung disease in rheumatoid arthritis
Interstitial lung disease in rheumatoid arthritis Open
Rheumatoid arthritis (RA) is a systemic inflammatory disorder mainly involving joints but almost 50% of the patients develop extra-articular manifestation, one of the most common being lung involvement. While essentially any of the lung co…
View article: Neurological manifestations in systemic lupus erythematosus: A case with an individualized therapeutic approach
Neurological manifestations in systemic lupus erythematosus: A case with an individualized therapeutic approach Open
Vasculitis occurs frequently in systemic lupus erythematosus (SLE) patients with an active disease and poor prognosis. Nervous system vasculitis – specifically, multiple mononeuropathy, seizures, and transverse myelitis – is among the most…
View article: Sex-specific difference in cardiac function in patients with systemic sclerosis: association with cardiovascular outcomes
Sex-specific difference in cardiac function in patients with systemic sclerosis: association with cardiovascular outcomes Open
Background Cardiovascular involvement is one of the leading causes of mortality in systemic sclerosis (SSc) and is reported to be higher in men as compared with women. However, the cause of this difference is largely unknown. The objective…
View article: A new CECR1 mutation associated with severe hematological involvement in ADA2 deficiency
A new CECR1 mutation associated with severe hematological involvement in ADA2 deficiency Open
Background The deficiency of adenosine deaminase 2 (DADA2) is an autosomal recessively inherited disease resulting from loss‐of‐function mutations in ADA2, formerly named CECR1 (cat eye syndrome chromosome region, candidate 1) gene. Diseas…
View article: Systemic sclerosis and primary biliary cholangitis: Longitudinal data to determine the outcomes
Systemic sclerosis and primary biliary cholangitis: Longitudinal data to determine the outcomes Open
Background: Several studies described the cross-sectional characteristics of systemic sclerosis patients and coexisting primary biliary cholangitis, but longitudinal prognostic data are lacking. Aims: To describe the systemic sclerosis–pri…
View article: Pancreatoduodenectomy for Malignant Solid Pseudopapillary Neoplasm in a Patient with Chronic Calcifying Pancreatitis, Rheumatoid Polyarthritis and Kidney Stones
Pancreatoduodenectomy for Malignant Solid Pseudopapillary Neoplasm in a Patient with Chronic Calcifying Pancreatitis, Rheumatoid Polyarthritis and Kidney Stones Open
We present the case of a patient with rheumatoid polyarthritis treated in our department, with a long history of chronic calcifying pancreatitis which was incidentaly diagnosed during a renal colic with a pancreatic tumor. Pancreatoduodene…
View article: A new CECR1 mutation associated with severe hematological involvement in ADA2 deficiency
A new CECR1 mutation associated with severe hematological involvement in ADA2 deficiency Open
Background : The deficiency of adenosine deaminase 2 (DADA2) is an autosomal recessively inherited disease resulting from loss-of-function mutations in ADA2, formerly named CECR1 (cat eye syndrome chromosome region, candidate 1) gene. Dise…