Mohammed A. Hussein
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View article: Ferulic acid-loaded chitosan nanoparticles enhance radiotherapy efficacy via STAT3 suppression and caspase-8/p53 activation in Ehrlich ascites carcinoma
Ferulic acid-loaded chitosan nanoparticles enhance radiotherapy efficacy via STAT3 suppression and caspase-8/p53 activation in Ehrlich ascites carcinoma Open
Radiotherapy resistance remains a major challenge in cancer treatment, necessitating novel strategies to enhance therapeutic efficacy while minimizing side effects. This study aimed to develop and evaluate ferulic acid-loaded chitosan nano…
View article: Metabolic identification of bioactive compounds of Citrus reticulata cultivars extracts for a novel approach to polycystic ovary syndrome
Metabolic identification of bioactive compounds of Citrus reticulata cultivars extracts for a novel approach to polycystic ovary syndrome Open
Polycystic ovary syndrome; is a prevalent endocrine disorder, characterized by hormonal imbalances, inflammation, and oxidative stress. Natural remedies, including Murcott and Merav ( Citrus reticulata varieties, Family: Rutaceae) fruits a…
View article: Prevalence and Factors Associated with Sepsis and Septic Shock Among ICU Patients at Adama Hospital Medical College: a Retrospective Chart Review Evaluating Outcome Predictive Performance of the Addition of Platelet Count on Modified SOFA Score
Prevalence and Factors Associated with Sepsis and Septic Shock Among ICU Patients at Adama Hospital Medical College: a Retrospective Chart Review Evaluating Outcome Predictive Performance of the Addition of Platelet Count on Modified SOFA Score Open
Background Sepsis and, its subset, septic shock are major health problems disproportionately affecting low- and middle-income countries. Despite the potentially high burden in low- and middle-income settings, data on prevalence and factors…
View article: Syzygium australe extracts exhibit significant antioxidant and antidiabetic properties: a comprehensive analysis of the phytoconstituents
Syzygium australe extracts exhibit significant antioxidant and antidiabetic properties: a comprehensive analysis of the phytoconstituents Open
Background Medicinal plants are well known for their health benefits. Syzygium australe (Brush Cherry) is considered a health-promoting food due to its high antioxidant capacity, which may help prevent cancer, cardiovascular diseases, and …
View article: Isolation and Identification of Clinical Bacterial Isolates and Their Resistance to Antibiotics and a Medicinal Plant Mixture (Turmeric, Ginger, and Indian Costus)
Isolation and Identification of Clinical Bacterial Isolates and Their Resistance to Antibiotics and a Medicinal Plant Mixture (Turmeric, Ginger, and Indian Costus) Open
BackgroundThe rise of antibiotic resistance in Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) has intensified the search for natural antibacterial alternatives. This study evaluates the antibacterial efficacy of ethanolic…
View article: Assessment of patient entrance surface and effective dose in the skull and thoraco-lumbar X-ray examinations
Assessment of patient entrance surface and effective dose in the skull and thoraco-lumbar X-ray examinations Open
Purpose: The review effort throughout the states was needed by the major concern of increased risk of cancer due to radiation exposure in patients during routine X-ray. This study aims to assess the patient entrance surface dosage during X…
View article: Chemosensitization and Molecular Docking Assessment of Dio-NPs on Resistant Breast Cancer Cells to Tamoxifen
Chemosensitization and Molecular Docking Assessment of Dio-NPs on Resistant Breast Cancer Cells to Tamoxifen Open
Background: Diosgenin, a powerful compound found in fenugreek and Dioscorea villosa, has diverse pharmacological effects. This study examines the anticancer potential of diosgenin nanoparticles (Dio-NPs) against DMBA-induced breast cancer …
View article: <b>Antioxidant and antimicrobial effect of butylated hydroxylanisole and carnosic acid on lamb meat under refrigerated storage</b>
<b>Antioxidant and antimicrobial effect of butylated hydroxylanisole and carnosic acid on lamb meat under refrigerated storage</b> Open
Background: The main causes of quality degradation of meat products are microbial growth and lipid oxidation, which decrease their shelf life. Carnosic acid, also known as CA, is a phenolic compound extracted from rosemary leaves and is co…
View article: Dihydro-Cucurbitacin-E; a Secondary Metabolite of Curvularia lunata's Biotransformation as a Promising cPLA-2 and sPLA-2 Inhibitor in B[a]P-Induced Lung Toxicity
Dihydro-Cucurbitacin-E; a Secondary Metabolite of Curvularia lunata's Biotransformation as a Promising cPLA-2 and sPLA-2 Inhibitor in B[a]P-Induced Lung Toxicity Open
Background Lung cancer is the most common cause of mortality, and its prevalence is rising quickly, making it a major global health concern. Numerous studies have indicated that benzo(a)pyrene [B[a]P] in cigarette smoke is the main cause o…
View article: A Systematic Review of Information Systems Association with Smart Technology from 3G to 5G
A Systematic Review of Information Systems Association with Smart Technology from 3G to 5G Open
The rapid evolution of telecommunications technology from 3G to 5G has profoundly impacted the landscape of smart technology and information systems. This systematic review examines the association between these technologies, focusing on t…
View article: Chemical composition, antioxidant, cytotoxic, antiviral, and lung-protective activities of Salvia officinalis L. ethanol extract herb growing in Sinai, Egypt
Chemical composition, antioxidant, cytotoxic, antiviral, and lung-protective activities of Salvia officinalis L. ethanol extract herb growing in Sinai, Egypt Open
Background Pulmonary fibrosis (PF) is a respiratory ailment that causes the substitution of healthy lung tissue with scar tissue due to collagen deposition and fibroblast proliferation. The incidence of PF increased with the successive wav…
View article: Utilizing video conferencing with families of critically ill non-COVID-19 patients during the pandemic curfew
Utilizing video conferencing with families of critically ill non-COVID-19 patients during the pandemic curfew Open
Background COVID-19 pandemic curfew made it difficult for families to communicate with their loved ones while hospitalized in the intensive care unit (ICU). A hybrid telephone and video conferencing model (VC) was created as a method of co…
View article: Clinical and Molecular Study of Canine Enteric Coronavirus in Iraq
Clinical and Molecular Study of Canine Enteric Coronavirus in Iraq Open
anine enteric coronavirus (CECoV) is one of the most common causes of gastrointestinal disorders in dogs, especially unvaccinated young dogs.This study was designed to determine the infection rate of CECoV in the dogs by reverse transcript…
View article: Effect of the Outer Pole Length on the Optical Properties in Gemini Lens
Effect of the Outer Pole Length on the Optical Properties in Gemini Lens Open
In order to get some of the most important optical and geometrical properties of scanning electron microscope lens, Such as focal length, lens aberration (spherical and chromatic aberration), Axial magnetic field distribution, trajectory o…
View article: Malva parviflora seed oil; Isolation, gas chromatographic profiling and its cardioprotective activity against myocardial infraction in animal model
Malva parviflora seed oil; Isolation, gas chromatographic profiling and its cardioprotective activity against myocardial infraction in animal model Open
Myocardial infarction (MI), one of the most perilous types of cardiac illness, carries a significant burden of mortality and morbidity. This study aims to shed light on the impact of Malva parviflora seed oil (MPSO) on plasma cardiac funct…
View article: Naringenin suppresses NLRP3 inflammasome activation via the mRNA-208a signaling pathway in isoproterenol-induced myocardial infarction
Naringenin suppresses NLRP3 inflammasome activation via the mRNA-208a signaling pathway in isoproterenol-induced myocardial infarction Open
Objective: To investigate the cardioprotective effect of naringenin against isoproterenol (ISO)-induced cardiotoxicity in rats. Methods: Rats were divided into five groups: the normal group, the ISO group (85 mg/kg b.w.); the ISO+naringeni…
View article: Structure Activity Relationship and Molecular Docking of Some Quinazolines Bearing Sulfamerazine Moiety as New 3CLpro, cPLA2, sPLA2 Inhibitors
Structure Activity Relationship and Molecular Docking of Some Quinazolines Bearing Sulfamerazine Moiety as New 3CLpro, cPLA2, sPLA2 Inhibitors Open
The current work was conducted to synthesize several novel anti-inflammatory quinazolines having sulfamerazine moieties as new 3CLpro, cPLA2, and sPLA2 inhibitors. The thioureido derivative 3 was formed when compound 2 was treated with sul…
View article: Effect of the Outer Pole Length on the Optical Properties in Gemini Lens
Effect of the Outer Pole Length on the Optical Properties in Gemini Lens Open
In order to get some of the most important optical and geometrical properties of scanning electron microscope lens, Such as focal length, lens aberration (spherical and chromatic aberration), Axial magnetic field distribution, trajectory o…
View article: Superficial and Inkjet Scalable Printed Sensors Integrated with Iron Oxide and Reduced Graphene Oxide for Sensitive Voltammetric Determination of Lurasidone
Superficial and Inkjet Scalable Printed Sensors Integrated with Iron Oxide and Reduced Graphene Oxide for Sensitive Voltammetric Determination of Lurasidone Open
The present work demonstrated the fabrication and the electrochemical characterization of novel printed electrochemical sensors integrated with an innovative nanosensing platform based on the synergic electrocatalytic effect of iron oxide …
View article: Chitosan Surface-Modified PLGA Nanoparticles Loaded with Cranberry Powder Extract as a Potential Oral Delivery Platform for Targeting Colon Cancer Cells
Chitosan Surface-Modified PLGA Nanoparticles Loaded with Cranberry Powder Extract as a Potential Oral Delivery Platform for Targeting Colon Cancer Cells Open
Nutraceutical cranberry powder extract (CBPE) has distinct polyphenols inhibiting colon cancer growth and proliferation. However, its oral therapeutic efficacy is hindered because of its low permeability. This study aims to formulate chito…
View article: Evidence on hospital accreditation to leverage its prospects for improvement
Evidence on hospital accreditation to leverage its prospects for improvement Open
Evaluating the quality of healthcare services is essential for performance improvements. Accreditation is widely regarded as the most frequently used external evaluation tool for assessing the quality of healthcare services. Accreditation …
View article: Numerical identification of timewise dependent coefficient in Hyperbolic inverse problem
Numerical identification of timewise dependent coefficient in Hyperbolic inverse problem Open
This article investigates the nonlocal inverse initial boundary-value problem in a rectangular domain, hyperbolic second order inverseproblem. The main objective is to find the unidentified coefficient and offer a solution to the problem. …
View article: A Case of Paraneoplastic NMOSD With Sarcoma and Unusual Cauda Equina Enhancement
A Case of Paraneoplastic NMOSD With Sarcoma and Unusual Cauda Equina Enhancement Open
Objective To describe a case of sarcoma associated with NMOSD presenting with myeloradiculitis. Background Neuromyelitis optica is a demyelinating disease of the CNS that predominantly affects the spinal cord and optic nerves. Reports of N…