R. L. Neetha
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View article: Discovery of potential small molecule inhibitors against β-hCG: an <i>in silico</i> study with <i>in vitro</i> validation
Discovery of potential small molecule inhibitors against β-hCG: an <i>in silico</i> study with <i>in vitro</i> validation Open
After screening 127 846 molecules from various virtual libraries, we demonstrated for the first time the anticancer efficacy of cefotetan, an antibacterial agent, in β-hCG-expressing BRCA1-defective breast cancer cell lines.
View article: Mast cells as prognostic indicator in spontaneous canine mammary carcinomas
Mast cells as prognostic indicator in spontaneous canine mammary carcinomas Open
Tumour micro-environment is essential to nourish the cancer stem cells (CSC) which are said to be the major cause to initiate recurrence/ metastasis. Though there are many players, mast cells are said to play a key role in tumour metastasi…
View article: Partial genome analysis of cox1 subunit-I region in mitochondrial dna of canine mammary tumours
Partial genome analysis of cox1 subunit-I region in mitochondrial dna of canine mammary tumours Open
Oncogenesis is an area which continuously elicits research interest. There are innumerable factors which contribute to oncogenesis of which mitochondrial DNA (mtDNA) mutations play a major role. Though extensive studies have been conducted…