L. Savelli
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View article: Premature rupture of the membranes in twin pregnancies: Maternal and fetal outcomes
Premature rupture of the membranes in twin pregnancies: Maternal and fetal outcomes Open
In our cohort of twin pregnancies no significative risk factors for premature rupture of membranes were found. Although PROM is known to increase infectious morbidity, not all patients will develop these complications. PROM in twin pregnan…
View article: Imaging in gynecological disease (29): clinical and ultrasound features of primary ovarian immature teratoma
Imaging in gynecological disease (29): clinical and ultrasound features of primary ovarian immature teratoma Open
Objective To describe the clinical and ultrasound characteristics at the time of diagnosis of primary ovarian immature teratoma with no other germ cell tumor components described on histopathology. Methods This was a retrospective study of…
View article: Reply to Douxfils, J.; Foidart, J.-M. Critical Considerations in the Interpretation of Bone Turnover Marker Data in HormonalContraceptive Users. Comment on “Tassi et al. Hormonal Contraception and Bone Metabolism: Emerging Evidence from a Systematic Review and Meta-Analysis of Studies on Post-Pubertal and Reproductive-Age Women. Pharmaceuticals 2025, 18, 61”
Reply to Douxfils, J.; Foidart, J.-M. Critical Considerations in the Interpretation of Bone Turnover Marker Data in HormonalContraceptive Users. Comment on “Tassi et al. Hormonal Contraception and Bone Metabolism: Emerging Evidence from a Systematic Review and Meta-Analysis of Studies on Post-Pubertal and Reproductive-Age Women. Pharmaceuticals 2025, 18, 61” Open
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View article: Hormonal Contraception and Bone Metabolism: Emerging Evidence from a Systematic Review and Meta-Analysis of Studies on Post-Pubertal and Reproductive-Age Women
Hormonal Contraception and Bone Metabolism: Emerging Evidence from a Systematic Review and Meta-Analysis of Studies on Post-Pubertal and Reproductive-Age Women Open
Background/Objectives: This study aims to assess the effects of combined hormonal contraceptives (CHCs) on bone metabolism markers. It primarily measures osteocalcin and additionally examines other bone health markers, seeking to determine…
View article: EP23.48: Rhabdoid tumour of the ovary: clinical and ultrasound characteristics of five cases of small cell carcinoma hypercalcemic type
EP23.48: Rhabdoid tumour of the ovary: clinical and ultrasound characteristics of five cases of small cell carcinoma hypercalcemic type Open
status: Published
View article: OC05.06: Clinical and ultrasound characteristics of ovarian cancers arising from mature cystic teratoma
OC05.06: Clinical and ultrasound characteristics of ovarian cancers arising from mature cystic teratoma Open
status: Published
View article: OC05.01: *Prospective validation of an end‐to‐end machine learning‐based model for the classification of adnexal masses using ultrasonography
OC05.01: *Prospective validation of an end‐to‐end machine learning‐based model for the classification of adnexal masses using ultrasonography Open
status: Published
View article: Machine learning and radiomics for segmentation and classification of adnexal masses on ultrasound
Machine learning and radiomics for segmentation and classification of adnexal masses on ultrasound Open
Ultrasound-based models exist to support the classification of adnexal masses but are subjective and rely upon ultrasound expertise. We aimed to develop an end-to-end machine learning (ML) model capable of automating the classification of …
View article: OC03.08: Automated segmentation and radiomics based classification of adnexal masses on ultrasound
OC03.08: Automated segmentation and radiomics based classification of adnexal masses on ultrasound Open
findings in pre-and postpubertal CAYAs differ from adults and diagnostic models are not validated.We aim to assess the incidence and management of ovarian pathology in this cohort.Methods: Retrospective review of pelvic USS performed in CA…
View article: EP26.08: Imaging in gynecological disease: clinical and ultrasound characteristics of uterine malignant mixed Müllerian tumours
EP26.08: Imaging in gynecological disease: clinical and ultrasound characteristics of uterine malignant mixed Müllerian tumours Open
Objectives: ACUM or ''Accessory Cavitated Uterine Malformation'' is a relatively rare and recently recognised uterine abnormality.It has been defined as a non-communicating accessory uterine cavity with functional endometrium, located at t…
View article: The Use of Machine Learning Models and Radiomics for Segmentation and Classification of Adnexal Masses on Ultrasound: A multi-cohort retrospective study
The Use of Machine Learning Models and Radiomics for Segmentation and Classification of Adnexal Masses on Ultrasound: A multi-cohort retrospective study Open
Background Ovarian cancer remains the deadliest of all gynaecological cancers. Ultrasound-based models exist to support the classification of adnexal masses but are dependent on human assessment of features on ultrasound. Therefore, we aim…
View article: Data from External Validation of Diagnostic Models to Estimate the Risk of Malignancy in Adnexal Masses
Data from External Validation of Diagnostic Models to Estimate the Risk of Malignancy in Adnexal Masses Open
Purpose: To externally validate and compare the performance of previously published diagnostic models developed to predict malignancy in adnexal masses.Experimental Design: We externally validated the diagnostic performance of 11 models de…
View article: Data from External Validation of Diagnostic Models to Estimate the Risk of Malignancy in Adnexal Masses
Data from External Validation of Diagnostic Models to Estimate the Risk of Malignancy in Adnexal Masses Open
Purpose: To externally validate and compare the performance of previously published diagnostic models developed to predict malignancy in adnexal masses.Experimental Design: We externally validated the diagnostic performance of 11 models de…
View article: Supplementary Table from External Validation of Diagnostic Models to Estimate the Risk of Malignancy in Adnexal Masses
Supplementary Table from External Validation of Diagnostic Models to Estimate the Risk of Malignancy in Adnexal Masses Open
PDF file - 94K
View article: Supplementary Tables 1-8, Supplementary Figure 1 from Clinical Utility of Risk Models to Refer Patients with Adnexal Masses to Specialized Oncology Care: Multicenter External Validation Using Decision Curve Analysis
Supplementary Tables 1-8, Supplementary Figure 1 from Clinical Utility of Risk Models to Refer Patients with Adnexal Masses to Specialized Oncology Care: Multicenter External Validation Using Decision Curve Analysis Open
Supplementary Table 1. Validated prediction models; Supplementary Table 2. Data contributed to dataset 1 per center; Supplementary Table 3. Net Benefit of the LR2 model by IOTA (LR2), the Risk of Malignancy Index (RMI at cut-off 200), the …
View article: Supplementary Table from External Validation of Diagnostic Models to Estimate the Risk of Malignancy in Adnexal Masses
Supplementary Table from External Validation of Diagnostic Models to Estimate the Risk of Malignancy in Adnexal Masses Open
PDF file - 94K
View article: Data from Clinical Utility of Risk Models to Refer Patients with Adnexal Masses to Specialized Oncology Care: Multicenter External Validation Using Decision Curve Analysis
Data from Clinical Utility of Risk Models to Refer Patients with Adnexal Masses to Specialized Oncology Care: Multicenter External Validation Using Decision Curve Analysis Open
Purpose: To evaluate the utility of preoperative diagnostic models for ovarian cancer based on ultrasound and/or biomarkers for referring patients to specialized oncology care. The investigated models were RMI, ROMA, and 3 models from the …
View article: Data from Clinical Utility of Risk Models to Refer Patients with Adnexal Masses to Specialized Oncology Care: Multicenter External Validation Using Decision Curve Analysis
Data from Clinical Utility of Risk Models to Refer Patients with Adnexal Masses to Specialized Oncology Care: Multicenter External Validation Using Decision Curve Analysis Open
Purpose: To evaluate the utility of preoperative diagnostic models for ovarian cancer based on ultrasound and/or biomarkers for referring patients to specialized oncology care. The investigated models were RMI, ROMA, and 3 models from the …
View article: Supplementary Tables 1-8, Supplementary Figure 1 from Clinical Utility of Risk Models to Refer Patients with Adnexal Masses to Specialized Oncology Care: Multicenter External Validation Using Decision Curve Analysis
Supplementary Tables 1-8, Supplementary Figure 1 from Clinical Utility of Risk Models to Refer Patients with Adnexal Masses to Specialized Oncology Care: Multicenter External Validation Using Decision Curve Analysis Open
Supplementary Table 1. Validated prediction models; Supplementary Table 2. Data contributed to dataset 1 per center; Supplementary Table 3. Net Benefit of the LR2 model by IOTA (LR2), the Risk of Malignancy Index (RMI at cut-off 200), the …
View article: Benign descriptors and <scp>ADNEX</scp> in two‐step strategy to estimate risk of malignancy in ovarian tumors: retrospective validation in <scp>IOTA5</scp> multicenter cohort
Benign descriptors and <span>ADNEX</span> in two‐step strategy to estimate risk of malignancy in ovarian tumors: retrospective validation in <span>IOTA5</span> multicenter cohort Open
Objective Previous work has suggested that the ultrasound‐based benign simple descriptors (BDs) can reliably exclude malignancy in a large proportion of women presenting with an adnexal mass. This study aimed to validate a modified version…
View article: Advanced low grade serous ovarian cancer: A retrospective analysis of surgical and chemotherapeutic management in two high volume oncological centers
Advanced low grade serous ovarian cancer: A retrospective analysis of surgical and chemotherapeutic management in two high volume oncological centers Open
Simple summary Low-grade serous ovarian cancer (LGSOC) represents an uncommon histotype of serous ovarian cancer (accounting for approximately 5% of all ovarian cancer) with a distinct behavior compared to its high-grade serous counterpart…
View article: Endometriosis and the Urinary Tract: From Diagnosis to Surgical Treatment
Endometriosis and the Urinary Tract: From Diagnosis to Surgical Treatment Open
We aim to describe the diagnosis and surgical management of urinary tract endometriosis (UTE). We detail current diagnostic tools, including advanced transvaginal ultrasound, magnetic resonance imaging, and surgical diagnostic tools such a…
View article: Endometriosis and the Urinary Tract: from Diagnosis to Surgical Treatment
Endometriosis and the Urinary Tract: from Diagnosis to Surgical Treatment Open
We aim to describe the diagnosis and surgical management of urinary tract endometriosis (UTE). We detail current diagnostic tools including advanced transvaginal ultrasound, magnetic resonance imaging, and surgical diagnostic tools such as…
View article: Vessel morphology depicted by three‐dimensional power Doppler ultrasound as second‐stage test in adnexal tumors that are difficult to classify: prospective diagnostic accuracy study
Vessel morphology depicted by three‐dimensional power Doppler ultrasound as second‐stage test in adnexal tumors that are difficult to classify: prospective diagnostic accuracy study Open
Objectives To assess whether vessel morphology depicted by three‐dimensional (3D) power Doppler ultrasound improves discrimination between benignity and malignancy if used as a second‐stage test in adnexal masses that are difficult to clas…
View article: Validation of models to diagnose ovarian cancer in patients managed surgically or conservatively: multicentre cohort study
Validation of models to diagnose ovarian cancer in patients managed surgically or conservatively: multicentre cohort study Open
Objective To evaluate the performance of diagnostic prediction models for ovarian malignancy in all patients with an ovarian mass managed surgically or conservatively. Design Multicentre cohort study. Setting 36 oncology referral centres (…