L. Solymosi
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View article: Histopathologic Characterization and Neurodegenerative Markers in Patients With Limbic Encephalitis Undergoing Epilepsy Surgery
Histopathologic Characterization and Neurodegenerative Markers in Patients With Limbic Encephalitis Undergoing Epilepsy Surgery Open
Purpose Limbic encephalitis is an increasingly recognized cause of medial temporal lobe epilepsy (mTLE) and associated cognitive deficits, potentially resulting in hippocampal sclerosis (HS). For several reasons, these patients usually do …
View article: High Mobility Group Box 1 Protein in Cerebral Thromboemboli
High Mobility Group Box 1 Protein in Cerebral Thromboemboli Open
High-mobility group box 1 protein (HMGB1) is a damage-associated molecular pattern (DAMP) involved in neutrophil extracellular trap (NET) formation and thrombosis. NETs are regularly found in cerebral thromboemboli. We here analyzed associ…
View article: Endovascular Treatment for Acute Stroke in Cerebral Amyloid Angiopathy
Endovascular Treatment for Acute Stroke in Cerebral Amyloid Angiopathy Open
Background and Purpose: We aimed to compare outcome of endovascular thrombectomy in acute ischemic stroke in patients with and without cerebral amyloid angiopathy (CAA). Methods: We included patients with and without possible or probable C…
View article: MR-Imaging and Histopathological Diagnostic Work-Up of Patients with Spontaneous Lobar Intracerebral Hemorrhage: Results of an Institutional Prospective Registry Study
MR-Imaging and Histopathological Diagnostic Work-Up of Patients with Spontaneous Lobar Intracerebral Hemorrhage: Results of an Institutional Prospective Registry Study Open
Intracerebral hemorrhage (ICH) is a frequently disabling or fatal disease. The localization of ICH often allows an etiological association. However, in atypical/lobar ICH, the cause of bleeding is less obvious. Therefore, we present prospe…
View article: Temporal changes in total and hippocampal brain volume and cognitive function in patients with chronic heart failure—the COGNITION.MATTERS-HF cohort study
Temporal changes in total and hippocampal brain volume and cognitive function in patients with chronic heart failure—the COGNITION.MATTERS-HF cohort study Open
Aims We quantified the concurring dynamics affecting total and hippocampal brain volume and cognitive function in patients with chronic heart failure (HF) over a period of three years. Methods and results A total of 148 patients with mild …
View article: Sex Differences in Outcome After Thrombectomy for Acute Ischemic Stroke are Explained by Confounding Factors
Sex Differences in Outcome After Thrombectomy for Acute Ischemic Stroke are Explained by Confounding Factors Open
Purpose The aim of this study was to analyze sex differences in outcome after thrombectomy for acute ischemic stroke in clinical practice in a large prospective multicenter registry. Methods Data of consecutive stroke patients treated with…
View article: Resection of piriform cortex predicts seizure freedom in temporal lobe epilepsy
Resection of piriform cortex predicts seizure freedom in temporal lobe epilepsy Open
Objective Transsylvian selective amygdalo‐hippocampectomy (tsSAHE) represents a generally recognized surgical procedure for drug‐resistant mesial temporal lobe epilepsy (mTLE). Although postoperative seizure freedom can be achieved in abou…
View article: Immunohistological Analysis of Neutrophils and Neutrophil Extracellular Traps in Human Thrombemboli Causing Acute Ischemic Stroke
Immunohistological Analysis of Neutrophils and Neutrophil Extracellular Traps in Human Thrombemboli Causing Acute Ischemic Stroke Open
Ischemic stroke caused by thromboembolic occlusion of large cerebral arteries, such as the internal carotid (ICA) and/or the middle cerebral artery (MCA), is treated by mechanical thrombectomy (MT). MT allows salvage of the vessel-occludin…
View article: Derivo embolization device in the treatment of unruptured intracranial aneurysms: a prospective multicenter study
Derivo embolization device in the treatment of unruptured intracranial aneurysms: a prospective multicenter study Open
Background Flow diverters (FD) are used regularly for the endovascular treatment of unruptured intracranial aneurysms. We aimed to assess the safety and effectiveness of the Derivo embolization device (DED) with respect to long-term clinic…
View article: Functional Outcome Following Stroke Thrombectomy in Clinical Practice
Functional Outcome Following Stroke Thrombectomy in Clinical Practice Open
Background and Purpose— Endovascular treatment for large vessel occlusion in ischemic stroke has proven to be effective in large clinical trials. We aimed to provide real-world estimates of endovascular treatment reperfusion rates and func…
View article: Contrast-Enhanced CISS MRI Improves Visualization and Planning in Vestibular Schwannomas
Contrast-Enhanced CISS MRI Improves Visualization and Planning in Vestibular Schwannomas Open
Background Preoperative visualization is essential in planning of vestibular schwannoma operations. Still, there is often a considerable discrepancy between measured tumor size in MRI and intraoperative findings, especially regarding the i…
View article: Facial Nerve Elongation in Vestibular Schwannomas: A Useful Aspect with Regard to Functional Preservation
Facial Nerve Elongation in Vestibular Schwannomas: A Useful Aspect with Regard to Functional Preservation Open
Background The facial nerve is mostly displaced and stretched in an anterior direction in vestibular schwannomas. Preoperative visualization may be partially achieved by Gadolinium-enhanced CISS MRI (Gd-Ciss). The individual tumor shape an…
View article: Carotid dissection presenting as a prolonged cluster-like headache in a patient with episodic cluster headache
Carotid dissection presenting as a prolonged cluster-like headache in a patient with episodic cluster headache Open
We present a patient with known episodic cluster headache, who presented with cluster-like headache in the course of internal carotid artery dissection (ICAD) and discuss possible pathophysiological links between the two diseases. It is we…
View article: Pathogenic<b>inflammation in the CNS of mice carrying human<i>PLP1</i>mutations</b>
Pathogenic<b>inflammation in the CNS of mice carrying human<i>PLP1</i>mutations</b> Open
Progressive forms of multiple sclerosis lead to chronic disability, substantial decline in quality of life and reduced longevity. It is often suggested that they occur independently of inflammation. Here we investigated the disease progres…
View article: 3D rotational fluoroscopy for intraoperative clip control in patients with intracranial aneurysms – assessment of feasibility and image quality
3D rotational fluoroscopy for intraoperative clip control in patients with intracranial aneurysms – assessment of feasibility and image quality Open
This technique quickly supplies images at adequate quality to evaluate distal vessel patency after aneurysm clipping. Significant aneurysm remnants may be depicted as well. As it does not require visual control of all vessels that are supp…