Hong Lin
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View article: Ferroptosis in human reproductive tract infections and associated disorders: mechanisms and emerging therapeutic opportunities
Ferroptosis in human reproductive tract infections and associated disorders: mechanisms and emerging therapeutic opportunities Open
Ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxidation, is closely associated with mitochondrial damage, diminished glutathione peroxidase 4 activity, dysfunction of the System Xc − cystine/glutamate antip…
View article: Dietary Supplement Strategies During Conditioning Training in Athletes: A Network Meta‐Analysis of Peak and Mean Anaerobic Power, <scp>VO</scp> <sub>2</sub> max, and Endurance Performance
Dietary Supplement Strategies During Conditioning Training in Athletes: A Network Meta‐Analysis of Peak and Mean Anaerobic Power, <span>VO</span> <sub>2</sub> max, and Endurance Performance Open
Dietary supplements are often used during training to support energy provision, recovery, and adaptation, yet effects on peak and mean anaerobic power, VO 2 max, and endurance performance remain inconsistent. Unlike prior syntheses centred…
View article: The impact of 6-week flywheel eccentric training on sprint speed and change-of-direction of female basketball players
The impact of 6-week flywheel eccentric training on sprint speed and change-of-direction of female basketball players Open
Given the demands of basketball for rapid sprinting and directional changes, and the growing interest in flywheel eccentric training (FET) to enhance these abilities, this study examines a six-week FET regimen compared to barbell squat tra…
View article: Correction: Enhanced anti−tumor efficacy of “IL−15 and CCL19” −secreting CAR−T cells in human glioblastoma orthotopic xenograft model
Correction: Enhanced anti−tumor efficacy of “IL−15 and CCL19” −secreting CAR−T cells in human glioblastoma orthotopic xenograft model Open
[This corrects the article DOI: 10.3389/fonc.2025.1539055.].
View article: Systematic analysis of ZDHHC9 as a potential prognostic and immunotherapy biomarker in breast cancer
Systematic analysis of ZDHHC9 as a potential prognostic and immunotherapy biomarker in breast cancer Open
Background Breast cancer (BC) represents a highly heterogeneous malignancy and continues to be a leading source of death among women worldwide. Enhancing diagnostic and therapeutic approaches necessitates a thorough grasp of the underlying…
View article: Sensitive SERS Platform for the Detection of <i>Staphylococcus aureus</i> via Freezing SERS Tags and Core–Shell Aptamer-Au@Fe<sub>3</sub>O<sub>4</sub> Nanoparticles
Sensitive SERS Platform for the Detection of <i>Staphylococcus aureus</i> via Freezing SERS Tags and Core–Shell Aptamer-Au@Fe<sub>3</sub>O<sub>4</sub> Nanoparticles Open
The detection of Staphylococcus aureus is crucial for the diagnosis and treatment of infectious diseases. However, developing a simple and sensitive method for S. aureus detection remains challenging. Herein, we propose a sensitive surface…
View article: Enhanced Detection of Permafrost Deformation with Machine Learning and Interferometric SAR Along the Qinghai–Tibet Engineering Corridor
Enhanced Detection of Permafrost Deformation with Machine Learning and Interferometric SAR Along the Qinghai–Tibet Engineering Corridor Open
Interferometric synthetic aperture radar (InSAR) plays a significant role in monitoring permafrost deformation. However, owing to environmental constraints in permafrost regions, some regions exhibit temporal incoherence, which results in …
View article: USIS16K: High-Quality Dataset for Underwater Salient Instance Segmentation
USIS16K: High-Quality Dataset for Underwater Salient Instance Segmentation Open
Inspired by the biological visual system that selectively allocates attention to efficiently identify salient objects or regions, underwater salient instance segmentation (USIS) aims to jointly address the problems of where to look (salien…
View article: Live bacteria found in gastric cancer tumor tissue
Live bacteria found in gastric cancer tumor tissue Open
Background Most research on gastric cancer and microorganisms has focused on Helicobacter pylori as a causative agent and on the relationship between the microbiota and gastric cancer. There is no direct evidence of bacteria in gastric can…
View article: A novel strategy to precisely adjust partition coefficient, effectively eliminate matrix interference and achieve accurate and fast gold immunochromatographic assay of ethoxyquin in aquatic products
A novel strategy to precisely adjust partition coefficient, effectively eliminate matrix interference and achieve accurate and fast gold immunochromatographic assay of ethoxyquin in aquatic products Open
Ethoxyquin (EQ), a common antioxidant in animal feed and aquatic products, poses health risks such as hepatorenal damage and teratogenicity. Conventional detection methods, while sensitive, are often complex and costly. This study introduc…
View article: Anoikis-Related Genes Can Accurately Predict the Occurrence of Endometriosis: A Retrospective Cohort Study via Machine Learning Analysis
Anoikis-Related Genes Can Accurately Predict the Occurrence of Endometriosis: A Retrospective Cohort Study via Machine Learning Analysis Open
Endometriosis is one of the most common benign gynecological disorders, characterized by persistent pain and challenges with fertility. Anoikis, a specific form of apoptosis, occurs when cells detach from the extracellular matrix. Recent r…
View article: Preparation of Polymyxin B-Functionalized Cryogels for Efficient Endotoxin Removal from Protein Solutions
Preparation of Polymyxin B-Functionalized Cryogels for Efficient Endotoxin Removal from Protein Solutions Open
To address the limitations of traditional endotoxin adsorbents, which exhibit poor endotoxin removal efficiency and low sample recovery when processing high-concentration samples, a novel cryogel, CG(HEMA-co-AM), based on acrylamide (AM) a…
View article: Estrogen and viral infection
Estrogen and viral infection Open
Gender differences exist in the susceptibility, incidence, progression, and prognosis of diseases caused by viral infections. These differences are influenced by various factors, including lifestyle and habits between males and females. So…
View article: Estrogen and bacterial infection
Estrogen and bacterial infection Open
Gender differences exist in the susceptibility, incidence, progression, and prognosis of bacterial infections in males and females, influenced by various factors including lifestyle and habits. Multiple reports have indicated that estrogen…
View article: Evaluation of bigano snail (<i>Stramonita haemastoma</i>) as a seafood resource
Evaluation of bigano snail (<i>Stramonita haemastoma</i>) as a seafood resource Open
Bigano snail, Stramonita haemastoma , commonly known as oyster drill or red‐mouthed rock whelks, has gained growing interest as a potential seafood product. However, to date, there is a notable lack of preliminary evaluation regarding its …
View article: The disulfidptosis-related lncRNAs can predict survival and immunotherapyresponse accurately in endometrial carcinoma
The disulfidptosis-related lncRNAs can predict survival and immunotherapyresponse accurately in endometrial carcinoma Open
Endometrial cancer of the uterine corpus (ECUC) is a common malignancy among females. Disulfidptosis, a recently identified form of cellular death, is characterized by elevated SLC7A11 expression and limited glucose availability, making it…
View article: Enhanced anti−tumor efficacy of “IL−15 and CCL19” −secreting CAR−T cells in human glioblastoma orthotopic xenograft model
Enhanced anti−tumor efficacy of “IL−15 and CCL19” −secreting CAR−T cells in human glioblastoma orthotopic xenograft model Open
Despite the remarkable success of CAR-T cell therapy in hematologic malignancies, its progress in solid tumors has been slow. Overcoming challenges such as the recruitment and infiltration of CAR-T cells into the tumor site and the surviva…
View article: The relationship between ferroptosis and respiratory infectious diseases: a novel landscape for therapeutic approach
The relationship between ferroptosis and respiratory infectious diseases: a novel landscape for therapeutic approach Open
Respiratory infectious diseases, particularly those caused by respiratory viruses, have the potential to lead to global pandemics, thereby posing significant threats to public and human health. Historically, the primary treatment for respi…
View article: Nanodot‐Inspired Precise Bacterial Gene Suppression in a Smart Hydrogel Bandage for Underwater Wound Healing
Nanodot‐Inspired Precise Bacterial Gene Suppression in a Smart Hydrogel Bandage for Underwater Wound Healing Open
The complex and dynamic nature of aquatic ecosystems, particularly in marine environments, makes managing wound infections a significant challenge for individuals engaged in underwater activities and for aquatic organisms. Although antibio…
View article: Insights into the recognition mechanism of shark-derived single-domain antibodies with high affinity and specificity targeting fluoroquinolones
Insights into the recognition mechanism of shark-derived single-domain antibodies with high affinity and specificity targeting fluoroquinolones Open
In this study, we investigated the molecular recognition mechanisms of shark-derived single-domain antibodies (ssdAbs) targeting fluoroquinolones using an integrated approach that combines in silico homologous modeling, molecular dynamics …
View article: Complete genome analysis and biological characterization of phage vB_Bsu_hmny2 infecting Bacillus subtilis
Complete genome analysis and biological characterization of phage vB_Bsu_hmny2 infecting Bacillus subtilis Open
Bacillus subtilis, a key microorganism in food fermentation, is frequently compromised by phage contamination, which can result in fermentation failures. Therefore, understanding and controlling these phages is critical for enhancing ferme…
View article: Application of high-frequency ventilation combined with closed-loop automatic oxygen control therapy in neonatal respiratory distress syndrome
Application of high-frequency ventilation combined with closed-loop automatic oxygen control therapy in neonatal respiratory distress syndrome Open
Objective In the realm of retrospective research, the researcher embarked on a comprehensive inquiry with the primary aim of assessing the effectiveness and safety of high-frequency oscillatory ventilation (HFOV) in conjunction with closed…
View article: Outer Membrane Vesicle Production by Escherichia coli Enhances Its Defense against Phage Infection
Outer Membrane Vesicle Production by Escherichia coli Enhances Its Defense against Phage Infection Open
Several studies have investigated the multifunctional characteristics of outer membrane vesicles (OMVs), but research on their role in mediating phage–bacteria interactions is limited. Employing Escherichia coli as a model, we engineered a…
View article: Impact of mobile Internet use on health-seeking behaviors: evidence from China
Impact of mobile Internet use on health-seeking behaviors: evidence from China Open
Introduction Although health-seeking behaviors are crucial to China’s healthcare delivery system, the influence of mobile Internet use in this context remains under-explored. This study aimed to comprehensively explore the influence of mob…
View article: From Llama to Nanobody: A Streamlined Workflow for the Generation of Functionalised VHHs
From Llama to Nanobody: A Streamlined Workflow for the Generation of Functionalised VHHs Open
Nanobodies are recombinant antigen-specific single domain antibodies (VHHs) derived from the heavy chain–only subset of camelid immunoglobulins. Their small molecular size, facile expression, high affinity, and stability have combined to m…
View article: PqsA mutation-mediated enhancement of phage-mediated combat against Pseudomonas aeruginosa
PqsA mutation-mediated enhancement of phage-mediated combat against Pseudomonas aeruginosa Open
Phage therapy is a potential approach in the biocontrol of foodborne pathogens. However, the emergence of phage resistance and the narrow host range of most phage isolates continue to limit the antimicrobial efficacy of phages. Here, we in…