Lingling Wang
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View article: Septic Shock Precipitating a Pheochromocytoma Crisis: A Case of Sequential Acute Myocardial Infarction and Cardiogenic Shock
Septic Shock Precipitating a Pheochromocytoma Crisis: A Case of Sequential Acute Myocardial Infarction and Cardiogenic Shock Open
View article: Corrigendum to “PD-1+/CXCR6+CD8+T lymphocytes promote MASLD malignant progression through inflammatory and immune dysregulation” [Int. Immunopharmacol. 168 (2026) 115847]
Corrigendum to “PD-1+/CXCR6+CD8+T lymphocytes promote MASLD malignant progression through inflammatory and immune dysregulation” [Int. Immunopharmacol. 168 (2026) 115847] Open
View article: Knowledge, attitude, and practice regarding brucellosis among confirmed cases
Knowledge, attitude, and practice regarding brucellosis among confirmed cases Open
Brucellosis remains a major public health problem in many endemic regions of China, particularly in areas with extensive livestock farming. This study aims to explore the knowledge, attitudes, and practices regarding brucellosis among pati…
View article: GMrepo v3: a curated human gut microbiome database with expanded disease coverage and enhanced cross-dataset biomarker analysis
GMrepo v3: a curated human gut microbiome database with expanded disease coverage and enhanced cross-dataset biomarker analysis Open
GMrepo (Gut Microbiome Data Repository) is a curated and consistently annotated database of human gut metagenomes, designed to improve data reusability and enable cross-project and cross-disease comparisons. In this latest release, GMrepo …
View article: PD-1+/CXCR6+CD8+T lymphocytes promote MASLD malignant progression through inflammatory and immune dysregulation
PD-1+/CXCR6+CD8+T lymphocytes promote MASLD malignant progression through inflammatory and immune dysregulation Open
Metabolic dysfunction-associated steatotic liver disease (MASLD) is closely linked to hepatocellular carcinoma (HCC), but the role of CD8+ T cells from MASLD to HCC progression is unclear. This study investigates the dynamic cha…
View article: AI‐Guided SERS Defines a Pan‐Cancer Diagnostic Biomarker
AI‐Guided SERS Defines a Pan‐Cancer Diagnostic Biomarker Open
Early and accurate detection of multiple cancers through a single test remains an unmet clinical need, hindered by current limitations in accuracy, throughput, automation, and multiplexing. Here, we present an AI‐powered SERS chip that com…
View article: Stage-specific gut microbial restructuring drives estrous transition in rabbits
Stage-specific gut microbial restructuring drives estrous transition in rabbits Open
These findings demonstrate that gut microbiota restructuring regulates the estrous transition of rabbits, providing a basis for developing microbiota-targeted strategies to enhance reproductive efficiency in rabbit production and optimize …
View article: Baicalin inhibits infectious bronchitis virus replication via MAVS-dependent interferon-β upregulation and mitochondrial function preservation
Baicalin inhibits infectious bronchitis virus replication via MAVS-dependent interferon-β upregulation and mitochondrial function preservation Open
View article: Effect of Boundary-layer Suction on the Performance of an Intake under Off-design Condition
Effect of Boundary-layer Suction on the Performance of an Intake under Off-design Condition Open
Under off-design conditions, shock wave-boundary layer interaction (SWBLI) and large-scale separation within the intake become prominent, leading to significant decrease in aerodynamic performance. By introducing a boundary layer suction s…
View article: Research on the conversion pattern of 6-gingerol in stir-fried ginger and the protective activity mechanism of its conversion products on HUVECs
Research on the conversion pattern of 6-gingerol in stir-fried ginger and the protective activity mechanism of its conversion products on HUVECs Open
Gingerol compounds are the main active and spicy components in ginger, among which 6-gingerol has the highest content. Gingerol compounds have an unstable structure due to multiple phenolic hydroxyl groups. During drying, heating, and proc…
View article: Preoperative systemic inflammation response index may predict postoperative delayed extubation for elderly patients with aSAH: a retrospective cohort study
Preoperative systemic inflammation response index may predict postoperative delayed extubation for elderly patients with aSAH: a retrospective cohort study Open
View article: Intratracheal administration: Non-invasive approach for liver-targeted siRNA-LNP delivery
Intratracheal administration: Non-invasive approach for liver-targeted siRNA-LNP delivery Open
View article: Interpretable Machine Learning Model for Predicting 1-Year Unplanned Readmissions in Ischemic Stroke Patients with Diabetes: A Synergistic View of Inflammation and Metabolism
Interpretable Machine Learning Model for Predicting 1-Year Unplanned Readmissions in Ischemic Stroke Patients with Diabetes: A Synergistic View of Inflammation and Metabolism Open
The ML model based on inflammatory and metabolic biomarkers effectively predicts 1-year unplanned readmission risk in IS patients with T2DM, with good interpretability and clinical potential. The dynamic nomogram enables real-time, individ…
View article: Pilot Design for Block Compressed Sensing-Based MIMO-OFDM Channel Estimation with Joint Criterion
Pilot Design for Block Compressed Sensing-Based MIMO-OFDM Channel Estimation with Joint Criterion Open
This paper studies the pilot design for compressed sensing (CS)-based sparse channel estimation in multi-input–multi-output orthogonal frequency division multiplexing (MIMO-OFDM) systems. To improve the performance of estimating multiple j…
View article: Dual-Mode Aptamer AP1-F Achieves Molecular–Morphological Precision in Cancer Diagnostics via Membrane NCL Targeting
Dual-Mode Aptamer AP1-F Achieves Molecular–Morphological Precision in Cancer Diagnostics via Membrane NCL Targeting Open
Nucleic acid aptamers leverage defined tertiary structures for precise molecular recognition, positioning them as transformative biomedical tools. We engineered AP1-F, a G-quadruplex (G4)-structured aptamer that selectively binds membrane-…
View article: Predicting Immunotherapy Outcomes in NSCLC Using RNA and Pathology from Multicenter Clinical Trials
Predicting Immunotherapy Outcomes in NSCLC Using RNA and Pathology from Multicenter Clinical Trials Open
Immune checkpoint inhibitors (ICIs) are widely used to treat advanced non‐small cell lung cancer (NSCLC). However, it remains crucial to identify patients who are unlikely to benefit from immunotherapy and to explore potential combination …
View article: Bridging the gap: Computer-aided detection and Yamada classification system matches expert performance
Bridging the gap: Computer-aided detection and Yamada classification system matches expert performance Open
BACKGROUND Computer-aided diagnosis (CAD) may assist endoscopists in identifying and classifying polyps during colonoscopy for detecting colorectal cancer. AIM To build a system using CAD to detect and classify polyps based on the Yamada c…
View article: Upper-limb symptom clusters and their associations with surgical complications among breast cancer survivors: A cross-sectional study
Upper-limb symptom clusters and their associations with surgical complications among breast cancer survivors: A cross-sectional study Open
Breast cancer survivors experienced distinct symptom clusters that were significantly associated with surgical complications. These findings highlight the importance of targeted prevention and management strategies, particularly for seroma…
View article: Integrating Peridynamic Theory with Ground Fissure Mechanics: Application to Songzhuang Ground Fissure Study
Integrating Peridynamic Theory with Ground Fissure Mechanics: Application to Songzhuang Ground Fissure Study Open
This study explores the application of Peridynamic (PD) theory in ground fissure modeling and simulation, focusing on the Songzhuang region in Beijing. Traditional methods often encounter difficulties in accurately capturing fissure format…
View article: Toward Precision Nutrition Standards: Molecular Profiling of GSE OPCs and Gaps in Current Regulations
Toward Precision Nutrition Standards: Molecular Profiling of GSE OPCs and Gaps in Current Regulations Open
Grape seed extract (GSE) is widely utilized in functional foods and dietary supplements due to its antioxidant and anti-aging potential, with much of its bioactivity attributed to oligomeric proanthocyanidins (OPCs). However, current quali…
View article: AI‐Assisted Detection of Early Gastric Cancer via Visualization of Mucosal Acidity Compromise During Endoscopy
AI‐Assisted Detection of Early Gastric Cancer via Visualization of Mucosal Acidity Compromise During Endoscopy Open
Accurate localization of early gastric cancer (EGC) remains challenging due to its morphological resemblance to gastritis. This study presents an artificial intelligence (AI)‐assisted bedside diagnostic system to enhance EGC detection by v…
View article: Toward Precision Nutrition Standards: Molecular Profiling of GSE OPCs and Gaps in Current Regulations
Toward Precision Nutrition Standards: Molecular Profiling of GSE OPCs and Gaps in Current Regulations Open
Grape seed extract (GSE) is widely utilized in functional foods and dietary supplements due to its antioxidant and anti-aging potential, with much of its bioactivity attributed to oligomeric proanthocyanidins (OPCs). However, current quali…
View article: The integrated analysis of SIRT family expression, prognostic value, and potential implications in childhood acute lymphoblastic leukemia
The integrated analysis of SIRT family expression, prognostic value, and potential implications in childhood acute lymphoblastic leukemia Open
Background Acute lymphoblastic leukemia (ALL) is a rapidly progressive hematological malignancy caused by the dysregulated proliferation and abnormal differentiation or differentiation block of lymphoid precursors. The sirtuin family, as a…
View article: The Impact of Artificial Intelligence on Corporate Revenue Growth: Evidence from China
The Impact of Artificial Intelligence on Corporate Revenue Growth: Evidence from China Open
Technological innovation in the AI sector is rapidly advancing, with achievements like AI patents emerging as key assets in corporate competition. While the direct revenue from individual patents may be limited in the short term, leveragin…
View article: Optimizing nursing care for neutropenic patients: a holistic perspective on education, support, and clinical management
Optimizing nursing care for neutropenic patients: a holistic perspective on education, support, and clinical management Open
Neutropenia, characterized by neutrophil counts below 1,500 cells/μL, increases infection risk and worsens treatment outcomes in oncology and immunocompromised patients. This paper outlines evidence-based nursing strategies in four domains…
View article: Volatile distribution inversion and rotation analysis of comet 103P/Hartley 2 using nongravitational effects
Volatile distribution inversion and rotation analysis of comet 103P/Hartley 2 using nongravitational effects Open
Aims . The rotational states of comet 103P/Hartley 2 (103P) during its perihelion passage are strongly modulated by nongravitational forces. By fitting its attitude-variation measurements, this study aims to infer the spatial distributions…
View article: Self-Assemblied Fe-Zol Nanoparticles In Neutrophils Promote Osteonecrosis Progression
Self-Assemblied Fe-Zol Nanoparticles In Neutrophils Promote Osteonecrosis Progression Open
Aim or purpose: To explore the mechanisms of bisphosphonate-related osteonecrosis of jaw (BRONJ) based on plasticity and iron metabolism in jawbone neutrophils. Materials and methods: Jawbone and femur injury model with/without Zoldronate …
View article: Editorial: Progress in clinical and mechanistic studies of severe respiratory viral infections in children
Editorial: Progress in clinical and mechanistic studies of severe respiratory viral infections in children Open
View article: Embryonic and Larval Development of an Interspecific Grouper Backcross Between the Kelp Grouper (Epinephelus moara) ♀ and KGGG (E. moara ♀ × E. lanceolatus ♂) ♂
Embryonic and Larval Development of an Interspecific Grouper Backcross Between the Kelp Grouper (Epinephelus moara) ♀ and KGGG (E. moara ♀ × E. lanceolatus ♂) ♂ Open
Backcrossing serves as an effective tool for interspecific gene introgression, facilitating germplasm improvement. To develop superior grouper aquaculture varieties, in this study, a backcrossed breed was constructed by crossing a male hyb…
View article: Association between history of pregnancy loss and preterm birth: the mediating role of maternal anxiety
Association between history of pregnancy loss and preterm birth: the mediating role of maternal anxiety Open
A history of pregnancy loss, prenatal anxiety, and preterm birth are interconnected. Prenatal anxiety takes a potential role in mediating the relationship between a history of pregnancy loss and the risk of preterm birth. Women with a hist…