Feng Zhu
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View article: Identification and human risk assessment of key active chemicals released from plastic food packaging: integrating lipidomics and suspect screening
Identification and human risk assessment of key active chemicals released from plastic food packaging: integrating lipidomics and suspect screening Open
View article: Accelerating scientific discovery with the common task framework
Accelerating scientific discovery with the common task framework Open
Machine learning (ML) and artificial intelligence (AI) algorithms are transforming and empowering the characterization and control of dynamic systems in the engineering, physical, and biological sciences. These emerging modeling paradigms …
View article: Mechanisms of superior respiratory IgA responses against SARS-CoV-2 after mucosal vaccination 2158
Mechanisms of superior respiratory IgA responses against SARS-CoV-2 after mucosal vaccination 2158 Open
Description Mucosal immunization and respiratory IgA responses offer significant promise in protecting against airborne pathogens, including SARS-CoV-2. However, However, the conditions and mechanisms that lead to the robust induction of r…
View article: Risk based ranking of prioritized pesticides: where the exposome meets comparative toxicogenomics
Risk based ranking of prioritized pesticides: where the exposome meets comparative toxicogenomics Open
Pesticides play an essential role in modern agricultural systems by enhancing crop yields and controlling pest-related losses and are applied extensively across the globe. However, their pervasive use has led to widespread environmental co…
View article: An active high-entropy air electrode for enhanced reversible solid oxide cell performance and stability
An active high-entropy air electrode for enhanced reversible solid oxide cell performance and stability Open
The insufficient stability and poor surface reaction kinetics (i.e., oxygen reduction reaction (ORR) and oxygen evolution reaction (OER)) of air electrodes are significant factors hindering the development of reversible solid oxide cells (…
View article: The effect of solid solution treatment on the microstructure and properties of CoCrMo alloy (Erratum)
The effect of solid solution treatment on the microstructure and properties of CoCrMo alloy (Erratum) Open
View article: Property evolution and driving factors of electrolytic manganese residue (EMR) during long-term natural weathering
Property evolution and driving factors of electrolytic manganese residue (EMR) during long-term natural weathering Open
Electrolytic manganese residue (EMR), a waste by-product of manganese production, poses significant ecological risks. Natural succession remediation provides a sustainable strategy for risk control; however, the long-term evolution of EMR …
View article: Lacticaseibacillus rhamnosus GR-1 prevents autism-like behaviors by reshaping the maternal and offspring microbiome
Lacticaseibacillus rhamnosus GR-1 prevents autism-like behaviors by reshaping the maternal and offspring microbiome Open
As a prevalent neurodevelopmental disease, whether ASD (autism spectrum disorder) can be ameliorated by the early use of a single microbe remains unknown. Here we used a lactobacillus strain, Lacticaseibacillus rhamnosus GR-1 (LGR-1), for …
View article: The λ pattern on time-RR interval scatter plot of neonatal ambulatory ECG: a marker of transient bradycardia
The λ pattern on time-RR interval scatter plot of neonatal ambulatory ECG: a marker of transient bradycardia Open
Background Neonatal bradycardia often triggers transient escape rhythms that challenge clinical diagnosis, with current methods lacking dynamic biomarkers for risk stratification. Objective To validate the λ pattern, a heart rate dynamic s…
View article: Geographic origin discrimination and quantification of phenolic compounds and moisture in Artemisia argyi folium using NIRS and chemometrics
Geographic origin discrimination and quantification of phenolic compounds and moisture in Artemisia argyi folium using NIRS and chemometrics Open
Artemisia argyi Folium (AAF), the leaf of the perennial plant Artemisia argyi H. Léveillé & Vaniot, has a long history of medicinal and edible use in East Asia. This study developed a rapid method, which integrated near-infrared spectrosco…
View article: The Time Effect of the Impact of the Body Roundness Index on Kidney Disease: A Cluster Analysis Based on Longitudinal Data
The Time Effect of the Impact of the Body Roundness Index on Kidney Disease: A Cluster Analysis Based on Longitudinal Data Open
Background Central obesity is a key modifiable risk factor for kidney disease. The Body Round-ness Index (BRI) is useful for assessing central obesity and associated metabolic risks. This study aimed to investigate the correlation between …
View article: Correlation of serum miR-203a-3p with the severity of neonates with necrotizing enterocolitis and analysis of its molecular mechanism
Correlation of serum miR-203a-3p with the severity of neonates with necrotizing enterocolitis and analysis of its molecular mechanism Open
Objectives The objective of this study was to examine the role of microRNA-203a-3p (miR-203a-3p) in the pathogenesis of necrotizing enterocolitis (NEC). Methods Quantitative real-time polymerase chain reaction (qRT-PCR) and receiver operat…
View article: Toxicity Characterization, Detection and Remediation of Contaminants in Soils and Groundwater
Toxicity Characterization, Detection and Remediation of Contaminants in Soils and Groundwater Open
Soil and groundwater contamination remains a critical environmental and public health challenge worldwide [...]
View article: Global, regional and national burdens of otitis media in children and adolescents from 1990 to 2021 and its predictions to 2040
Global, regional and national burdens of otitis media in children and adolescents from 1990 to 2021 and its predictions to 2040 Open
Background Otitis media (OM), including acute OM, chronic OM, and OM with effusion, is associated with varying degrees of hearing impairment. Children and adolescents (CAAs) are particularly vulnerable to OM. However, epidemiological data …
View article: Wurtzite AlScN/AlN Superlattice Ferroelectrics Enable Endurance Beyond 1010 Cycles
Wurtzite AlScN/AlN Superlattice Ferroelectrics Enable Endurance Beyond 1010 Cycles Open
Wurtzite ferroelectrics are rapidly emerging as a promising material class for next-generation non-volatile memory technologies, owing to their large remanent polarization, intrinsically ordered three-dimensional crystal structure, and ful…
View article: 366 | EVOLVING TREATMENT LANDSCAPE AND OUTCOMES IN ELDERLY HODGKIN LYMPHOMA: A 15‐YEAR MULTICENTER RETROSPECTIVE ANALYSIS FROM CHINA HIGHLIGHTING THE IMPACT OF NOVEL THERAPIES
366 | EVOLVING TREATMENT LANDSCAPE AND OUTCOMES IN ELDERLY HODGKIN LYMPHOMA: A 15‐YEAR MULTICENTER RETROSPECTIVE ANALYSIS FROM CHINA HIGHLIGHTING THE IMPACT OF NOVEL THERAPIES Open
View article: 642 | REAL‐WORLD EFFICACY AND SAFETY OF GLOFITAMAB IN CHINESE PATIENTS WITH R/R DLBCL: HIGH RESPONSE RATES IN HIGH‐RISK POPULATIONS
642 | REAL‐WORLD EFFICACY AND SAFETY OF GLOFITAMAB IN CHINESE PATIENTS WITH R/R DLBCL: HIGH RESPONSE RATES IN HIGH‐RISK POPULATIONS Open
View article: Preparation, characterization, in vitro, and in vivo assessment of bortezomib-loaded poly (ethylene glycol)-distearyl phosphatidylethanolamine nanomicelles
Preparation, characterization, in vitro, and in vivo assessment of bortezomib-loaded poly (ethylene glycol)-distearyl phosphatidylethanolamine nanomicelles Open
Multiple myeloma (MM) is a prevalent hematologic malignancy, and bortezomib (BTZ), as the first proteasome inhibitor, has significant effects in the treatment of MM. However, BTZ suffers from low water solubility, poor in vivo stability, a…
View article: Health care use preceding pediatric multiple sclerosis: A population-based study from Ontario, Canada
Health care use preceding pediatric multiple sclerosis: A population-based study from Ontario, Canada Open
Background: Investigations of a prodrome in multiple sclerosis (MS) usually have included adults. Objective: To compare rates and reasons for health care use in youth with and without MS, considering time relative to the MS index date and …
View article: Ultra-flexible anti-freezing cellulose conductive hydrogel for energy storage and self-powered sensors
Ultra-flexible anti-freezing cellulose conductive hydrogel for energy storage and self-powered sensors Open
View article: The impact of antibiotic use on outcomes of relapsed/refractory multiple myeloma patients treated with CAR-T therapy
The impact of antibiotic use on outcomes of relapsed/refractory multiple myeloma patients treated with CAR-T therapy Open
Background In recent years, chimeric antigen receptor (CAR)-T cell therapy has achieved tremendous efficacy in relapsed/refractory multiple myeloma (R/R MM). However, the impact of antibiotic (ATB) use on R/R MM patients treated with CAR-T…
View article: Cryogenic Ferroelectric Behavior of Wurtzite Ferroelectrics
Cryogenic Ferroelectric Behavior of Wurtzite Ferroelectrics Open
This study presents the first experimental exploration into cryogenic ferroelectric behavior in wurtzite ferroelectrics. A breakdown field (EBD) to coercive field (EC) ratio of 1.8 is achieved even at 4 K, marking the lowest ferroelectric …
View article: Synergistic multi-metal stabilization of lead–zinc smelting contaminated soil by Ochrobactrum EEELCW01-loaded iron-modified biochar: performance and long-term efficacy
Synergistic multi-metal stabilization of lead–zinc smelting contaminated soil by Ochrobactrum EEELCW01-loaded iron-modified biochar: performance and long-term efficacy Open
Nonferrous metal smelting has led to multi-metal pollution at many sites, which strongly threatens ecosystem and human health. Stabilization is a widely used method for remediating contaminated sites in China, Europe, and the United States…
View article: GlycoRNA-rich, neutrophil membrane-coated, siMT1-loaded nanoparticles mitigate abdominal aortic aneurysm progression by inhibiting the formation of neutrophil extracellular traps
GlycoRNA-rich, neutrophil membrane-coated, siMT1-loaded nanoparticles mitigate abdominal aortic aneurysm progression by inhibiting the formation of neutrophil extracellular traps Open
Abdominal aortic aneurysm (AAA) is a life-threatening vascular condition. Currently, there are no clinically available pharmacological interventions that can stop the progression of AAA, primarily due to the incomplete understanding of its…
View article: Lacticaseibacillus rhamnosus GR-1 prevents autism-like behaviors by reshaping the maternal and offspring microbiome
Lacticaseibacillus rhamnosus GR-1 prevents autism-like behaviors by reshaping the maternal and offspring microbiome Open
As a prevalent neurodevelopmental disease, whether ASD (autism spectrum disorder) can be ameliorated by the early use of a single microbe remains unknown. Here we report that Lacticaseibacillus rhamnosus GR-1 (LGR-1) prevented the occurren…
View article: Evaluating the Role of High‐Dimensional Proxy Data in Confounding Adjustment in Multiple Sclerosis Research: A Case Study
Evaluating the Role of High‐Dimensional Proxy Data in Confounding Adjustment in Multiple Sclerosis Research: A Case Study Open
Purpose Given the historical use of limited confounders in multiple sclerosis (MS) studies utilizing administrative health data, this brief report evaluates the impact of incorporating high‐dimensional proxy information on confounder adjus…
View article: Healthcare use is elevated two decades before a first demyelinating event and differs by age and sex
Healthcare use is elevated two decades before a first demyelinating event and differs by age and sex Open
Objective Elevated healthcare use before multiple sclerosis (MS) onset suggests earlier opportunity to identify MS. Yet their timing and sociodemographic effects are unclear. We examined rates of healthcare use (and by age/sex) for >two de…
View article: Nursing for conical telescopic crown prosthodontics in treating periodontitis accompanied by dentition defects
Nursing for conical telescopic crown prosthodontics in treating periodontitis accompanied by dentition defects Open
Objective: We aimed to investigate the nursing technique and outcomes of conical telescopic crown prosthodontics for patients with periodontitis accompanied by dental defects. Methods: One hundred patients with chronic periodontitis and de…
View article: Seasonal Variations in the Structure and Function of the Gut Flora in Adult Male Rhesus Macaques Reared in Outdoor Colonies
Seasonal Variations in the Structure and Function of the Gut Flora in Adult Male Rhesus Macaques Reared in Outdoor Colonies Open
The seasonal variations that occur in the gut microbiota of healthy adult rhesus monkeys kept in outdoor groups under conventional rearing patterns and how these variations are affected by environmental variables are relatively poorly unde…
View article: Harnessing the phyllosphere microbiota of wild foxtail millet for designing beneficial cross-kingdom synthetic communities
Harnessing the phyllosphere microbiota of wild foxtail millet for designing beneficial cross-kingdom synthetic communities Open
Understanding the interplay between mechanisms in plant microbiome assembly and functioning of wild ancestors has led to the proposal of a novel strategy to enhance resilience to the (a)biotic stresses of domesticated crops. The challenge …