Laimar C. Garmo
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View article: Per- and polyfluorinated substances (PFAS) promote osteoclastogenesis and bone loss through PPARα activation
Per- and polyfluorinated substances (PFAS) promote osteoclastogenesis and bone loss through PPARα activation Open
View article: Targeting SCD in SCD-amplified prostate cancer inhibits growth in bone by modulating cellular stress, mTOR, and DNA damage pathways
Targeting SCD in SCD-amplified prostate cancer inhibits growth in bone by modulating cellular stress, mTOR, and DNA damage pathways Open
The bone microenvironment is abundant in adipocytes and fosters metastatic progression, but the underlying mechanisms are not fully understood. We hypothesize that Stearoyl-Coenzyme A Desaturase (SCD) acts as a tumor-promoting enzyme by mo…
View article: Adipocyte-driven unfolded protein response is a shared transcriptomic signature of metastatic prostate carcinoma cells
Adipocyte-driven unfolded protein response is a shared transcriptomic signature of metastatic prostate carcinoma cells Open