Lalith Jayasinghe
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View article: Rapid micropropagation and chemical profiling of in vitro plantlets and agarwood of Gyrinops walla Gaertn. by gas-chromatography and mass-spectrometry
Rapid micropropagation and chemical profiling of in vitro plantlets and agarwood of Gyrinops walla Gaertn. by gas-chromatography and mass-spectrometry Open
Gyrinops walla Garten., which is an endemic and endangered species of Sri Lanka, produces the world’s most expensive agarwood used in perfume industry. The high demand for agarwood has resulted in indiscriminate felling of trees, thus thre…
View article: Nutritional composition and bioactivity studies on edible soft stem of banana (Musa spp.)
Nutritional composition and bioactivity studies on edible soft stem of banana (Musa spp.) Open
Banana tree (Musa spp.) has a false stem called a pseudostem which, is an edible soft-stem. A study was executed to compare the nutritional composition, antioxidative and anti-hyperglycemic properties of soft-stem of four local varieties n…
View article: Evaluation of antioxidant, acetylcholinesterase, lipase, α-amylase, xanthine oxidase, and α-glucosidase enzyme inhibitory activities of Sri Lankan tea cultivars
Evaluation of antioxidant, acetylcholinesterase, lipase, α-amylase, xanthine oxidase, and α-glucosidase enzyme inhibitory activities of Sri Lankan tea cultivars Open
View article: Bioactivity Studies of Different Solvent Extracts of Defatted Residues From <i>Terminalia catappa</i> L. Seed Kernels
Bioactivity Studies of Different Solvent Extracts of Defatted Residues From <i>Terminalia catappa</i> L. Seed Kernels Open
Terminalia catappa Linn., also referred to as tropical almond or Indian almond, can play a significant role in improving food and nutritional security. The objective of this research was to assess the antioxidant, antihyperglycemic, and an…
View article: Nutritional Composition and Bioactive Properties of <i>Salicornia brachiata</i>: A Comparison of Drying Methods
Nutritional Composition and Bioactive Properties of <i>Salicornia brachiata</i>: A Comparison of Drying Methods Open
Objective Salicornia brachiata, an euhalophyte thriving in saline environments, can be processed into a dried powder (termed bio-salt) from its tender aerial parts. This study aimed to evaluate how three distinct drying methods; freeze-dry…
View article: Three New Dipeptide and Two New Polyketide Derivatives from the Mangrove-Derived Fungus Talaromyces sp.: Antioxidant Activity of Two Isolated Substances
Three New Dipeptide and Two New Polyketide Derivatives from the Mangrove-Derived Fungus Talaromyces sp.: Antioxidant Activity of Two Isolated Substances Open
Five new metabolites, including three cyclic dipeptide derivatives (1–3) and two new polyketides (10–11), together with nine known ones (4–9 and 12–15), were isolated from the mangrove-sediments-derived fungus Talaromyces sp. SCSIO 41431. …
View article: Characterization of oils and defatted residues of <i>Terminalia catappa</i> L. seed kernels of two varieties
Characterization of oils and defatted residues of <i>Terminalia catappa</i> L. seed kernels of two varieties Open
The seed kernel of Terminalia catappa Linn (T. catappa) is an underutilized plant food with promising potential. This study investigated the physicochemical properties, fatty acid composition, thermal behavior, and Fourier transform infrar…
View article: Secondary metabolites from the cold-seep-derived fungus Penicillium sp. SCSIO 41425 and their free radical scavenging activity
Secondary metabolites from the cold-seep-derived fungus Penicillium sp. SCSIO 41425 and their free radical scavenging activity Open
Objective: To study the chemical compositions from Penicillium sp. SCSIO 41425 and explore their DPPH radical scavenging activity. Methods: Ethyl acetate extract of Penicillium sp. SCSIO 41425 was separated and purified by silica gel, Osta…
View article: Variation of elastase, collagenase, tyrosinase enzyme inhibitory and antioxidant potential of different tea cultivars
Variation of elastase, collagenase, tyrosinase enzyme inhibitory and antioxidant potential of different tea cultivars Open
View article: Coconut Testa Flour Sub-Fractions: Correlation Between FTIR Spectral Data and α-Glucosidase Inhibitory Activities
Coconut Testa Flour Sub-Fractions: Correlation Between FTIR Spectral Data and α-Glucosidase Inhibitory Activities Open
Fourier-transform infrared spectroscopy (FTIR) serves as a rapid analytical technique to characterize food specimens chemically. The purpose of this study was to investigate the potential of FTIR combined with multivariate statistics to de…
View article: Toxic metal analysis of Sri Lankan Areca catechu varieties
Toxic metal analysis of Sri Lankan Areca catechu varieties Open
View article: Nutritional Composition, Anti-oxidative and Anti-hyperglycemic Potential of the Kernels of Two Varieties of <em>Terminalia catappa</em> L.
Nutritional Composition, Anti-oxidative and Anti-hyperglycemic Potential of the Kernels of Two Varieties of <em>Terminalia catappa</em> L. Open
Purpose: An attempt was made in this study to compare the differences in nutritional composition, antioxidant capacity, and anti-hyperglycemic effect of the kernel of purple and yellow varieties of Terminalia catappa L (T. catappa L).Resea…
View article: New Bioactive Polyketides from the Mangrove-Derived Fungus Penicillium sp. SCSIO 41411
New Bioactive Polyketides from the Mangrove-Derived Fungus Penicillium sp. SCSIO 41411 Open
Three new polyketides, including three ester derivatives (1, 3, and 5) and a new natural product, which was a benzoquinone derivative, embelin A (4), together with nine known ones (2 and 6–13), were isolated from the mangrove-derived fungu…
View article: Experimental study of mechanistic factors influencing solvent-driven fractional crystallization of calcium sulfate
Experimental study of mechanistic factors influencing solvent-driven fractional crystallization of calcium sulfate Open
View article: Preliminary Evaluation of Photoprotective Potential in Flowers of Osbeckia octandra (L.) DC. for Development of Herbal Sunscreen Formulations
Preliminary Evaluation of Photoprotective Potential in Flowers of Osbeckia octandra (L.) DC. for Development of Herbal Sunscreen Formulations Open
Introduction: Excessive exposure to ultraviolet (UV) radiation of the solar spectrum is often linked with the onset of conditions like inflammation, photoaging, immunosuppression, hyperpigmentation, and photocarcinogenesis. Although synthe…
View article: Development of herbal skin care formulations from the hydro-alcoholicextract of Leucas zeylanica (L.) W.T.Aiton
Development of herbal skin care formulations from the hydro-alcoholicextract of Leucas zeylanica (L.) W.T.Aiton Open
Introduction: Leucas zeylanica (L.) W.T.Aiton is a plant used in traditional medicine as a remedy against several dermatological conditions. The high UV-filtering potential observed for the aqueousmethanolic extract of this plant suggests …
View article: Molecular and phenotypic characterization of <em style="mso-bidi-font-style: normal;">Colletotrichum plurivorum</em> and <em style="mso-bidi-font-style: normal;">Colletotrichum</em> <em style="mso-bidi-font-style: normal;">musae</em> causing banana anthracnose disease in the Central Province of Sri Lanka
Molecular and phenotypic characterization of <em>Colletotrichum plurivorum</em> and <em>Colletotrichum</em> <em>musae</em> causing banana anthracnose disease in the Central Province of Sri Lanka Open
Most of the commercial banana cultivars in Sri Lanka are susceptible to anthracnose disease. Colletotrichum musae has been known as the causal agent of banana anthracnose for decades and the pathogen has been identified using morphological…
View article: Anti-oxidative, anti-hyperglycemic and anti-obesity properties of selected edible leafy plants of Sri Lanka
Anti-oxidative, anti-hyperglycemic and anti-obesity properties of selected edible leafy plants of Sri Lanka Open
Five selected edible leafy plants of Sri Lanka were studied in vitro to assess their anti-oxidative, anti-hyperglycemic and anti-obesity properties. Powdered samples of the leafy plants, namely Le-kola pala (LE), Kora kaha (KK), Koppa (KO)…
View article: FTIR spectral correlation with alpha-glucosidase inhibitory activities of selected leafy plants extracts
FTIR spectral correlation with alpha-glucosidase inhibitory activities of selected leafy plants extracts Open
Fourier transform infrared spectroscopy (FTIR) is a simple, rapid analytical technique used for the identification of organic functional groups of biomolecules. This study aimed to investigate the use of FTIR spectroscopy method for rapid …
View article: Development of Liquid Culture System for Rapid Multiplication of <em>Gyrinops walla</em>
Development of Liquid Culture System for Rapid Multiplication of <em>Gyrinops walla</em> Open
Agarwood is an expensive resinous compound, produced by Gyrinops walla as defence response to external damages. The tissue culture technique is the best alternative for both rapid multiplication and product synthesis. This study demonstrat…
View article: Development of herbal sunscreen formulations from the leaves of Sri Lankan medicinal plants, <em>Hibiscus furcatus</em> wild. and <em>Olax zeylanica</em> Linn
Development of herbal sunscreen formulations from the leaves of Sri Lankan medicinal plants, <em>Hibiscus furcatus</em> wild. and <em>Olax zeylanica</em> Linn Open
Excessive exposure to ultraviolet (UV) radiation in the sunlight has many deleterious consequences on human skin. In order to alleviate these harmful effects, sunscreen formulations are widely used. Although most of these synthetic sunscre…
View article: (<i>R</i>)-13a<i>α</i>-Densiindolizidine, A New Phenanthroindolizidine Alkaloid From <i>Cryptocarya densiflora</i> Blume (Lauraceae) and Molecular Docking Against SARS-CoV-2
(<i>R</i>)-13a<i>α</i>-Densiindolizidine, A New Phenanthroindolizidine Alkaloid From <i>Cryptocarya densiflora</i> Blume (Lauraceae) and Molecular Docking Against SARS-CoV-2 Open
Cryptocarya densiflora Blume (Lauraceae) is an evergreen tree widely distributed throughout the hills and mountain forests up to 1500 m in Malaysia and Indonesia. The plant has been reported to contain phenanthroindolizidine-type of alkalo…
View article: Frontmatter
Frontmatter Open
View article: Plectranthus zeylanicus: A Rich Source of Secondary Metabolites with Antimicrobial, Disinfectant and Anti-Inflammatory Activities
Plectranthus zeylanicus: A Rich Source of Secondary Metabolites with Antimicrobial, Disinfectant and Anti-Inflammatory Activities Open
Plectranthus zeylanicus Benth is used in Sri Lankan folk medicine as a remedy for inflammatory conditions and microbial infections. Our previous investigations revealed potent 5-lipoxygenase (5-LO) inhibitory activity in lipophilic extract…
View article: Mid-IR Spectral Characterization and Chemometric Evaluation of Different Solvent Extracts of Coconut Testa Flour
Mid-IR Spectral Characterization and Chemometric Evaluation of Different Solvent Extracts of Coconut Testa Flour Open
Fourier transform infrared (FTIR) spectroscopy is a fast analytical technique being successfully used in depicting the chemical characteristics of foods.The objective of this research was to use FTIR to characterize the fractionation behav…
View article: A new foliar disease of Ficus religiosa caused by Diaporthe acutispora, identified using molecular phylogeny based on multigene DNA sequence analyses
A new foliar disease of Ficus religiosa caused by Diaporthe acutispora, identified using molecular phylogeny based on multigene DNA sequence analyses Open
The Journal of the National Science Foundation of Sri Lanka publishes the results of research in all aspects of Science and Technology. The journal also has a website at http://www.nsf.gov.lk/. 2021 Impact Factor: 0.682The JNSF provides im…
View article: Molecular phylogeny-based identification of <em>Colletotrichum endophytica</em> and <em>C. siamense</em> as causal agents of avocado anthracnose in Sri Lanka
Molecular phylogeny-based identification of <em>Colletotrichum endophytica</em> and <em>C. siamense</em> as causal agents of avocado anthracnose in Sri Lanka Open
Avocado (Persea americana) is a sub-tropical fruit with high nutritional value and numerous health benefits. Among the postharvest fungal diseases that affect ripe avocados, anthracnose is one of the most destructive disease world…
View article: Anti-Fibrotic and Anti-Angiogenic Activities of Osbeckia octandra Leaf Extracts in Thioacetamide-Induced Experimental Liver Cirrhosis
Anti-Fibrotic and Anti-Angiogenic Activities of Osbeckia octandra Leaf Extracts in Thioacetamide-Induced Experimental Liver Cirrhosis Open
Chronic liver inflammation has become a major global health concern. In the absence of clinical surrogate markers to diagnose inflammatory liver disease, the intervention with effective drugs in modern medicine tends to be late. In Sri Lan…
View article: Volatile Profiling Aided in the Isolation of Anti-Proliferative Lupeol from the Roots of Clinacanthus nutans (Burm. f.) Lindau
Volatile Profiling Aided in the Isolation of Anti-Proliferative Lupeol from the Roots of Clinacanthus nutans (Burm. f.) Lindau Open
Isolation of anti-proliferative compounds from plants is always hindered by the complexities of the plant’s nature and tedious processes. Clinacanthus nutans (Burm. f.) Lindau is a medicinal plant with reported anti-proliferative activitie…
View article: The first report of <em>Helvella crispa</em> (Ascomycota, Pezizales), a rare fungal species in Sri Lanka
The first report of <em>Helvella crispa</em> (Ascomycota, Pezizales), a rare fungal species in Sri Lanka Open
Two striking, stipitate fruiting bodies of a fungus were found in Hantana area, bordering the Dunumadalawa Forest Reserve within the Kandy District (Central Province) of Sri Lanka. The apothecium was capitate, cap whitish and irregularly s…