Lamia Mbarek
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View article: A similar effect of fibrinogen on efficacy and safety of tenecteplase <i>versus</i> alteplase in acute ischemic cerebrovascular events (TRACE II) trial
A similar effect of fibrinogen on efficacy and safety of tenecteplase <i>versus</i> alteplase in acute ischemic cerebrovascular events (TRACE II) trial Open
Background and Objectives Hemostasis factors affecting clot patterns, particularly fibrinogen, may influence the effectiveness of intravenous thrombolysis (IVT). We aimed to investigate the impact of differences in fibrinogen plasma levels…
View article: Exploring Non‐Coding <scp>RNA</scp> Regulation of the Blood–Brain Barrier in Neurodegenerative Diseases: A Systematic Review
Exploring Non‐Coding <span>RNA</span> Regulation of the Blood–Brain Barrier in Neurodegenerative Diseases: A Systematic Review Open
Neurodegenerative diseases (NDs) are characterized by progressive neuronal loss and dysfunction, leading to significant cognitive and motor impairments. The disruption of the blood–brain barrier (BBB) integrity, a key regulator of central …
View article: Stroke Prognosis: The Impact of Combined Thrombotic, Lipid, and Inflammatory Markers
Stroke Prognosis: The Impact of Combined Thrombotic, Lipid, and Inflammatory Markers Open
Elevated D-dimer, Lp(a), and hs-CRP levels together increase the risk of functional disability and mortality one-year post-AIS more than any single biomarker.
View article: Predicting 3-month poor functional outcomes of acute ischemic stroke in young patients using machine learning
Predicting 3-month poor functional outcomes of acute ischemic stroke in young patients using machine learning Open
ML outperformed logistic regression, where XGBoost the boost was the best model for predicting poor functional outcomes in young AIS patients. It is important to consider living alone conditions with high severity scores to improve stroke …
View article: Ischemic Stroke in Young Tunisian Adults
Ischemic Stroke in Young Tunisian Adults Open
Introduction: Ischemic Stroke in young adults is a real public health problem; it’s a major cause of disability, alters quality of life and has a great socio-economic impact. Aim: determine risk factors and specify the etiology of arterial…
View article: Relationship between homocysteine, vitamin B9, vitamin B12 levels methylenetetrahydrofolate reductase (C677T, A1298C) polymorphisms, and cryptogenic stroke in Tunisian adults´ patients: a case-control study
Relationship between homocysteine, vitamin B9, vitamin B12 levels methylenetetrahydrofolate reductase (C677T, A1298C) polymorphisms, and cryptogenic stroke in Tunisian adults´ patients: a case-control study Open
the presence of homozygote MTHFR C677T or dual heterozygous MTHFR C66T and A1298C, which leads to elevated Hcy and deficiency of vitamin B9 plasma levels, is correlated with an increased risk of cryptogenic stroke occurrence among adult Tu…
View article: PB2434 GENETIC AND ACQUIRED THROMBOTIC RISK FACTORS IN CEREBRAL VENOUS THROMBOSIS: A STUDY FROM THE SOUTH OF TUNISIA.
PB2434 GENETIC AND ACQUIRED THROMBOTIC RISK FACTORS IN CEREBRAL VENOUS THROMBOSIS: A STUDY FROM THE SOUTH OF TUNISIA. Open
Background: Cerebral Venous Thrombosis (CVT) affecting young adults is considered as an uncommon form of venous thrombosis with a prominent mortality rate (6%). The clinical phenotype may vary among patients as a result of many common prot…
View article: PB2438 DEEP‐VEIN THROMBOSIS IN PATIENTS WITH FACTOR XI DEFICIENCY FROM THE SOUTH OF TUNISIA
PB2438 DEEP‐VEIN THROMBOSIS IN PATIENTS WITH FACTOR XI DEFICIENCY FROM THE SOUTH OF TUNISIA Open
Background: Clotting factor XI (FXI) plays a separate role in hemostasis and in thrombosis. Recently, researches had shown that a FXI plasmatic activity (FXI: Act) greater than 95% could represent a thrombotic risk factor. FXI deficiency b…
View article: PB1847 CONGENITAL COMBINED DEFECTS OF COAGULATION FACTORS FVII AND FX: ABOUT A TUNISIAN FAMILY.
PB1847 CONGENITAL COMBINED DEFECTS OF COAGULATION FACTORS FVII AND FX: ABOUT A TUNISIAN FAMILY. Open
Background: Combined factor VII (FVII) and factor X (FX) deficiency is considered as an extremely rare bleeding disorder. Only a few cases have been reported all over the world. According to the WFH (World Federation of Hemophilia) 2014, t…