Lampros Kousoulas
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View article: Zonulin family peptide is not a predictive marker for development of minor postoperative complications: an observational study in patients after colorectal surgery
Zonulin family peptide is not a predictive marker for development of minor postoperative complications: an observational study in patients after colorectal surgery Open
Background Postoperative complications after colorectal surgery are still challenging. Zonulin family peptide (ZFP) has been discussed as a potential marker of intestinal permeability and postoperative complications. The aim of this trial …
View article: Enhancing ascitic fungal infection diagnosis through next-generation sequencing: a pilot study in surgical ICU patients
Enhancing ascitic fungal infection diagnosis through next-generation sequencing: a pilot study in surgical ICU patients Open
Objectives Ascites, often associated with critical pathologies such as liver cirrhosis or bowel perforation, can be complicated by fungal infection, increasing mortality especially in intensive care settings and demanding rapid diagnosis a…
View article: The Impact of Surgery-Related Emotional Distress on Long-Term Outcome After Colorectal Surgery: An Observational Follow-Up
The Impact of Surgery-Related Emotional Distress on Long-Term Outcome After Colorectal Surgery: An Observational Follow-Up Open
Background: Preoperative emotional distress has been linked to adverse health outcomes, diminished quality of life, increased symptom burden after surgery, and poorer postoperative outcomes. Therefore, this study aimed to assess the impact…
View article: Multiple surgical revisions in patients with anastomotic leakage: A retrospective cohort analysis
Multiple surgical revisions in patients with anastomotic leakage: A retrospective cohort analysis Open
The occurrence of an anastomotic leakage is a serious and potentially life-threatening complication in visceral surgery, affecting up to 20% of patients with a newly created gastrointestinal anastomosis. Most patients with anastomotic leak…
View article: Severe hyperlactatemia in unselected surgical patients: retrospective analysis of prognostic outcome factors
Severe hyperlactatemia in unselected surgical patients: retrospective analysis of prognostic outcome factors Open
Background Etiology of hyperlactatemia in ICU patients is heterogeneous—septic, cardiogenic or hemorrhagic shock seem to be predominant reasons. Multiple studies show hyperlactatemia as an independent predictor for ICU mortality. Only limi…
View article: Severe hyperlactatemia in unselected surgical patients. Retrospective analysis of prognostic outcome factors.
Severe hyperlactatemia in unselected surgical patients. Retrospective analysis of prognostic outcome factors. Open
BACKGROUNDEtiology of hyperlactatemia in ICU patients is heterogeneous - septic, cardiogenic or hemorrhagic shock seem to be predominant reasons. Multiple studies show hyperlactatemia as an independent predictor for ICU mortality. Only lim…
View article: Surgery as an Emotional Strain: An Observational Study in Patients Undergoing Elective Colorectal Surgery
Surgery as an Emotional Strain: An Observational Study in Patients Undergoing Elective Colorectal Surgery Open
Recent research suggests an impact of psychological distress on postoperative outcomes in orthopedic and neurosurgery. It is widely unknown whether patients’ mood might affect the postoperative outcome and complication rate in colorectal s…
View article: Clinical characteristics and outcome of patients with acute mesenteric ischemia: a retrospective cohort analysis
Clinical characteristics and outcome of patients with acute mesenteric ischemia: a retrospective cohort analysis Open
View article: Ogilvie’s syndrome—is there a cutoff diameter to proceed with upfront surgery?
Ogilvie’s syndrome—is there a cutoff diameter to proceed with upfront surgery? Open
Purpose Although Ogilvie’s syndrome was first described about 70 years ago, its etiology and pathogenesis are still not fully understood. But more importantly, it is also not clear when to approach which therapeutic strategy. Methods Patie…
View article: High serum CA19–9 preoperatively reduces POPF risk after pancreatoduodenectomy in PDAC
High serum CA19–9 preoperatively reduces POPF risk after pancreatoduodenectomy in PDAC Open
Background: Recent groundbreaking work revealed CA19–9 is not only a tumor marker for PDAC. It also induces severe pancreatitis and promotes pancreatic fibrosis. The aim of this study was evaluation if due fibrosis CA19–9 may stratify for …
View article: Randomisierte kontrollierte multizentrische Studie zur Albuminersatztherapie im septischen Schock (ARISS)
Randomisierte kontrollierte multizentrische Studie zur Albuminersatztherapie im septischen Schock (ARISS) Open
View article: Adjuvant chemotherapy after surgery for pancreatic ductal adenocarcinoma: retrospective real-life data
Adjuvant chemotherapy after surgery for pancreatic ductal adenocarcinoma: retrospective real-life data Open
View article: The impact of immunosuppression on postoperative graft function after graft-unrelated surgery: a retrospective controlled cohort study
The impact of immunosuppression on postoperative graft function after graft-unrelated surgery: a retrospective controlled cohort study Open
The choice of immunosuppressant might have an impact on graft function and survival of kidney transplant recipients after graft-unrelated surgery. Further investigations are needed.
View article: Naturopathic Treatment and Complementary Medicine in Surgical Practice
Naturopathic Treatment and Complementary Medicine in Surgical Practice Open
Certain naturopathic treatments and complementary medical methods may be useful in postoperative care and deserve more intensive study. In the publications consulted for this review, no serious side effects were reported.
View article: Hemoadsorption in a Case of Severe Septic Shock and Necrotizing Fasciitis Caused by Nontraumatic Renal Rupture due to Pyelonephritis with Obstructive Uropathy
Hemoadsorption in a Case of Severe Septic Shock and Necrotizing Fasciitis Caused by Nontraumatic Renal Rupture due to Pyelonephritis with Obstructive Uropathy Open
Background . Nontraumatic renal rupture due to pyelonephritis with obstructive uropathy is an uncommon but life-threatening situation. Case Presentation . A 25-year-old female presented to the emergency department with acute worsening of a…
View article: Postoperative changes of the microbiome: are surgical complications related to the gut flora? A systematic review
Postoperative changes of the microbiome: are surgical complications related to the gut flora? A systematic review Open
View article: Clinical Characteristics and Outcomes of Surgical Patients with Intensive Care Unit Lengths of Stay of 90 Days and Greater
Clinical Characteristics and Outcomes of Surgical Patients with Intensive Care Unit Lengths of Stay of 90 Days and Greater Open
Background . The aim of this study was to evaluate the influence of prolonged length of stay in an intensive care unit (ICU) on the mortality and morbidity of surgical patients. Methods . We performed a monocentric and retrospective observ…