Shuang Hao
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View article: Current Trends in Revision Surgery After Breast Reconstruction in China: Insights from a Nationwide Cross-Sectional Survey
Current Trends in Revision Surgery After Breast Reconstruction in China: Insights from a Nationwide Cross-Sectional Survey Open
Introduction Revision surgery is an integral component of post-mastectomy breast reconstruction, aimed at enhancing breast aesthetics and improving patient satisfaction. While developed countries have established high rates of revision sur…
Effects of Freeze–Thaw Cycles on Soil Aggregate Stability and Organic Carbon Distribution Under Different Land Uses Open
Soil aggregates are critical determinants of soil erosion resistance and nutrient retention capacity, while freeze–thaw cycles (FTCs) induce the structural reorganization of soil aggregates, thereby altering soil stability and influencing …
View article: Empirical and projected economic burden of chronic myeloid leukaemia in Sweden from 2015 to 2030: A population‐based study
Empirical and projected economic burden of chronic myeloid leukaemia in Sweden from 2015 to 2030: A population‐based study Open
Summary Despite therapeutic advances and improved survival, the long‐term economic burden of chronic myeloid leukaemia (CML) remains under‐recognised given evolving treatment practices and fluctuating drug costs. We aimed to estimate and p…
View article: Potential therapeutic target in oncology: Protein palmitoylation (Review)
Potential therapeutic target in oncology: Protein palmitoylation (Review) Open
Post‑translational modifications (PTMs) of proteins, by altering the structural conformation of precursor polypeptides, play an indispensable role in augmenting the diversity and stability of the proteome. PTMs exert profound influence on …
View article: Prostate Cancer Testing Between Screening Rounds: Evidence from the STHLM3-MRI Trial
Prostate Cancer Testing Between Screening Rounds: Evidence from the STHLM3-MRI Trial Open
We observed a substantial testing rate of 33% between STHLM3-MRI screening rounds, but few PCa cases were detected among men with lower risk. Most cancers were diagnosed in the elevated-risk group. A reduction in opportunistic testing in l…
View article: Protocol for a multicentre, prospective, open-label, randomised controlled trial to compare PROs and safety outcomes between preoperative and postmastectomy radiotherapy in locally advanced breast cancer patients with immediate reconstruction via a deep inferior epigastric perforator flap (CAPPELLA) in China
Protocol for a multicentre, prospective, open-label, randomised controlled trial to compare PROs and safety outcomes between preoperative and postmastectomy radiotherapy in locally advanced breast cancer patients with immediate reconstruction via a deep inferior epigastric perforator flap (CAPPELLA) in China Open
Introduction Despite its therapeutic advantages, postmastectomy radiotherapy (PMRT) increases the risk of complications and often leads to poor cosmesis in women undergoing breast reconstruction. Preoperative radiotherapy followed by skin-…
Effects of Different Microplastics on Wheat’s (Triticum aestivum L.) Growth Characteristics and Rhizosphere Soil Environment Open
In order to reveal the effects of microplastics (MPs) on the growth and rhizosphere soil environmental effects of wheat (Triticum aestivum L.), three microplastic types (polypropylene MPs (PP-MPs), high-density polyethylene MPs (HDPE-MPs),…
OD23 Evolving Prostate Cancer Screening Strategies In Germany: A Cost–Utility Analysis Comparing Traditional And Emerging Modalities Open
Introduction In 2021, approximately 15,000 men in Germany died from prostate cancer (PCa). The national health policy is considering shifting from annual digital rectal examination (DRE)-based screening to an age-related prostate-specific …
View article: Loss in Overall and Quality‐Adjusted Life Expectancy for Patients With Chronic‐Phase Chronic Myeloid Leukemia
Loss in Overall and Quality‐Adjusted Life Expectancy for Patients With Chronic‐Phase Chronic Myeloid Leukemia Open
The introduction of tyrosine kinase inhibitors has considerably improved the life expectancy (LE) for patients with chronic myeloid leukemia (CML). Evaluating health‐related quality of life within the treatment pathway remains crucial. Usi…
Serpin B9 is Highly Expressed in Lung Adenocarcinoma and is Associated with Progression-Free Survival Open
The increased expression of Serpin B9 in LUAD tumor tissues is negatively linked to prognosis and immunotherapy efficacy. This underscores their potential as prognostic and therapeutic targets.
141P Integrative radiomic analysis of peri-tumoral and habitat zones for predicting major pathological response to neoadjuvant immunotherapy and chemotherapy in non-small cell lung cancer: A multicenter, retrospective, cohort study Open
It is crucial for clinical decision-making to identify non-small cell lung cancer (NSCLC) patients who are likely to achieve major pathological remission (MPR) following neoadjuvant immunotherapy and chemotherapy (NICT). Our study involved…
Bascom II combined with VSD treatment involving the preservation of tissue bridges for recurrent complex pilonidal sinuses with a literature review Open
This case explores the advantages and characteristics of combining various techniques in the treatment of recurrent complex pilonidal sinuses, emphasizes the utility of VSD as an adjunctive therapy for large lesions.
Latissimus dorsi flap – the main force in breast reconstruction for breast tumor in Chinese population Open
Background The latissimus dorsi flap (LDF) is the most commonly used autologous flap for breast reconstruction (BR) in China. We conducted this study to explore the current status of BR using LDF with/without implants. Methods This study w…
A Systematic Review and Meta-Analysis of Comparing Drainage Alone versus Drainage with Primary Fistula Treatment for the Perianal Abscess in Children Open
This systematic review and meta-analysis of nonrandomized studies (NRSs) aimed to evaluate the clinical efficacy and safety of two types of surgical interventions (respectively drainage alone and drainage with primary fistula treatment) fo…
Cost-effectiveness of Prostate Cancer Screening Using Magnetic Resonance Imaging or Standard Biopsy Based on the STHLM3-MRI Study Open
Importance The combination of prostate-specific antigen (PSA) testing with magnetic resonance imaging (MRI) for prostate cancer detection has rarely been evaluated in a screening context. The STHLM3-MRI screening-by-invitation study ( NCT0…
Cost-Effectiveness of the Stockholm3 Test and Magnetic Resonance Imaging in Prostate Cancer Screening: A Microsimulation Study Open
The Stockholm3 test with image-based screening may reduce screening-related harms and costs, while maintaining the health benefits from early detection of prostate cancer.
The Early-Stage Triple-Negative Breast Cancer Landscape Derives a Novel Prognostic Signature and Therapeutic Target Open
Purpose: Triple-negative breast cancer (TNBC) is a highly heterogeneous disease. Patients with early-stage TNBCs have distinct likelihood of distant recurrence. Current therapeutic guidance is still limited.Methods: We extracted transcript…
Cost-Effectiveness of Magnetic Resonance Imaging in Prostate Cancer Screening: A Microsimulation Study Open
MRI + TBx and MRI + TBx/SBx showed strong dominance over alternative screening strategies. MRI + TBx resulted in similar or marginally lower gains in QALYs and lower costs than MRI + TBx/SBx. MRI + TBx was considered the optimal choice amo…
Transcriptome Analysis Derives a Novel Prognostic 7-mRNA Signature in Early-Stage Triple-Negative Breast Cancer Open
Background: Triple-negative breast cancer (TNBC) is a highly heterogeneous disease and patients with early-stage TNBCs have distinct likelihood of distant recurrence. Methods: In this study, We extracted transcriptome data for 189 patholog…
The cost-effectiveness of prostate cancer screening using the Stockholm3 test Open
Objectives The European Randomized Study of Screening for Prostate Cancer found that prostate-specific antigen (PSA) screening reduced prostate cancer mortality, however the costs and harms from screening may outweigh any mortality reducti…
Sinomenine Can Inhibit the Growth and Invasion Ability of Retinoblastoma Cell through Regulating PI3K/AKT Signaling Pathway Open
Sinomenine was found to play anti-cancer functions in different type of cancers, while the mechanisms underlying the anticancer effects of sinomenine in retinoblastoma (RB) remains unclear. The present study was designed to explore the imp…