Xue Xiao
YOU?
Author Swipe
View article: Clinical advances in transcutaneous auricular vagus nerve stimulation for post-stroke disorders: state of the art and future perspectives
Clinical advances in transcutaneous auricular vagus nerve stimulation for post-stroke disorders: state of the art and future perspectives Open
Transcutaneous auricular vagus nerve stimulation (taVNS) has emerged as a promising non-invasive neuromodulation therapy for post-stroke disorders. This review synthesizes current evidence on the clinical efficacy and underlying mechanisms…
View article: Population-based nasopharyngeal carcinoma survival in southern China
Population-based nasopharyngeal carcinoma survival in southern China Open
Background Few population-based studies on nasopharyngeal carcinoma (NPC) prognosis exist. Such real-world data with complete follow-up are needed to enable accurate estimation of survival probabilities and monitor progress in early detect…
View article: REST elevation-dependent chromatin remodeling and alternative Grk6 transcript synthesis hyperactivates Cxcr4-Sdf1 signaling in cerebellar granule cell progenitors
REST elevation-dependent chromatin remodeling and alternative Grk6 transcript synthesis hyperactivates Cxcr4-Sdf1 signaling in cerebellar granule cell progenitors Open
RE1 Silencing Transcription Factor (REST) is a repressor of transcriptional initiation of genes involved in neurogenesis. Here, we show that conditional REST elevation in cerebellar granule cell progenitors (CGNPs) of REST TG mice perturbe…
View article: Phosphorylation of H3.3 at Serine 31 acts as a switch of nucleosome dynamics for transcription
Phosphorylation of H3.3 at Serine 31 acts as a switch of nucleosome dynamics for transcription Open
The incorporation of histone variant H3.3 into the genome plays a critical role in regulating gene transcription, genomic stability, and mitosis progression. However, the precise mechanisms underlying the influence of H3.3 on nucleosome st…
View article: Chronic Ozone Exposure and Its Role in the Development of Age-Related Cataracts: A Comprehensive Analysis
Chronic Ozone Exposure and Its Role in the Development of Age-Related Cataracts: A Comprehensive Analysis Open
View article: [Risk Factors for Mortality in Hemodialysis Patients With Gastrointestinal Bleeding].
[Risk Factors for Mortality in Hemodialysis Patients With Gastrointestinal Bleeding]. Open
For MHD patients with concomitant GIB, APTT, GBS, aCCI, and small intestinal vascular malformation are independent risk factors for in-hospital death.
View article: Optimal intrapleural therapy with alpha-hemolytic streptococci bio-product (Mannatide) in controlling malignant pleural effusion: a clustered systematic review and meta-analysis.
Optimal intrapleural therapy with alpha-hemolytic streptococci bio-product (Mannatide) in controlling malignant pleural effusion: a clustered systematic review and meta-analysis. Open
PROSPERO CRD42022338798.
View article: CRISPRi screen identifies FprB as a synergistic target for gallium therapy in Pseudomonas aeruginosa
CRISPRi screen identifies FprB as a synergistic target for gallium therapy in Pseudomonas aeruginosa Open
With the rise of antibiotic-resistant bacteria, non-antibiotic therapies like gallium gain increasing attention. Intravenous gallium nitrate is under Phase II clinical trials to treat chronic Pseudomonas aeruginosa infections in cystic fib…
View article: Loss of CDS1 impairs the tumorigenic characteristics of nasopharyngeal carcinoma by modulating lipid metabolism
Loss of CDS1 impairs the tumorigenic characteristics of nasopharyngeal carcinoma by modulating lipid metabolism Open
The accumulation of lipid droplets (LDs) enhancing nasopharyngeal carcinoma (NPC) cell migration. We reveals that CDP-diacylglycerol synthase 1 (CDS1), an inhibitor of LDs formation, is significantly downregulated in NPC. Restoring CDS1 ex…
View article: Lysine Carboxymethyl Cysteinate, as a Topical Glutathione Precursor, Protects Against Oxidative Stress and UVB Radiation-Induced Skin Damage
Lysine Carboxymethyl Cysteinate, as a Topical Glutathione Precursor, Protects Against Oxidative Stress and UVB Radiation-Induced Skin Damage Open
Lysine carboxymethyl cysteinate (LCC) is a synthetic substance obtained via lysine salification of S-carboxymethyl-cysteine. LCC has emerged as a promising glutathione (GSH) precursor. In this study, we sought to determine whether LCC coul…
View article: Association between problematic social media use and psychological distress among college students: a cross-sectional study in China exploring the mediating role of eating disorders
Association between problematic social media use and psychological distress among college students: a cross-sectional study in China exploring the mediating role of eating disorders Open
Objectives This study aimed to examine the mediating role of eating disorders in the association between problematic social media use (PSMU) and psychological distress, including anxiety, depression and stress, among Chinese college studen…
View article: Effect of Microplastics on the Bioavailability of (Semi-)Metals in the Soil Earthworm Eisenia fetida
Effect of Microplastics on the Bioavailability of (Semi-)Metals in the Soil Earthworm Eisenia fetida Open
Microplastics have a large surface area and hydrophobic characteristics, which helps them to easily adsorb organic matter and trace metals in soil. This interaction has the potential to alter soil physicochemical properties, affect the bio…
View article: Intrapleural administration with traditional Chinese medicine injections (Sophorae flavescentis preparations) in controlling malignant pleural effusion: a clustered systematic review and meta-analysis
Intrapleural administration with traditional Chinese medicine injections (Sophorae flavescentis preparations) in controlling malignant pleural effusion: a clustered systematic review and meta-analysis Open
Introduction Sophorae flavescentis ( kushen ) preparations are widely used to control malignant pleural effusion (MPE) through intrapleural perfusion. Objectives This analysis aims to verify the therapeutic values of perfusion with kushen …
View article: Metabolomic Reprogramming Induced by Benzo[a]pyene in Skin Keratinocytes and Protective Effects of Glutathione Amino Acid Precursors
Metabolomic Reprogramming Induced by Benzo[a]pyene in Skin Keratinocytes and Protective Effects of Glutathione Amino Acid Precursors Open
Background Pollutant particles can penetrate and accumulate in skin, leading to excessive oxidative stress, inflammation, and skin disorders. Reduced glutathione (GSH) is considered as “the master antioxidant” and major detoxification agen…
View article: Survival and adaptative strategies of Enterotoxigenic E. coli (ETEC) to the freshwater environment
Survival and adaptative strategies of Enterotoxigenic E. coli (ETEC) to the freshwater environment Open
Waterborne pathogenic enterobacteria are adapted for infection of human hosts but can also survive for long periods in water environments. To understand how the human pathogen enterotoxigenic Escherichia coli (ETEC) adapts to acute and lon…
View article: A Triple-Precursor Blend as a Topical Solution to Protect the Skin Against Environmental Damage
A Triple-Precursor Blend as a Topical Solution to Protect the Skin Against Environmental Damage Open
The epidermis acts as the body’s primary defense, relying on components like lipids, HA and GSH for skin barrier function, hydration and resistance to oxidative stress. However, limitations in the topical application of these biomolecules …
View article: pH-responsive cationic polymer-functionalized poly-ε-caprolactone microspheres scavenge cell-free-DNA to alleviate intestinal ischemia/reperfusion injury by inhibiting M1 macrophage polarization
pH-responsive cationic polymer-functionalized poly-ε-caprolactone microspheres scavenge cell-free-DNA to alleviate intestinal ischemia/reperfusion injury by inhibiting M1 macrophage polarization Open
View article: Trastuzumab Decreases the Expression of G1/S Regulators and Syndecan-4 Proteoglycan in Human Rhabdomyosarcoma
Trastuzumab Decreases the Expression of G1/S Regulators and Syndecan-4 Proteoglycan in Human Rhabdomyosarcoma Open
Rhabdomyosarcoma (RMS), the most common soft tissue sarcoma in children, arises from skeletal muscle cells that fail to differentiate terminally. Two subgroups of RMS, fusion-positive and fusion-negative RMS (FPRMS and FNRMS, respectively)…
View article: A 42-Year Statistic on the Dabie Vortices: Multiscale Temporal Characteristics and Associated Mechanisms, and Hourly Rainfall Features
A 42-Year Statistic on the Dabie Vortices: Multiscale Temporal Characteristics and Associated Mechanisms, and Hourly Rainfall Features Open
Over the middle reaches of the Yangtze River basin, there is an important type of mesoscale vortices, which are referred to as the Dabie vortex (DBV). DBV has formed a research focus for decades, as it frequently induces flash-flood-produc…
View article: Ultrasound combined with Adenosine 5′-Monophosphate Treatment: A Strategic Approach for enhancing the tenderness of chicken wooden breast meat
Ultrasound combined with Adenosine 5′-Monophosphate Treatment: A Strategic Approach for enhancing the tenderness of chicken wooden breast meat Open
This study aimed to evaluate the effects of ultrasound and adenosine 5'-monophosphate (AMP) treatments on the quality characteristics and tenderness of chicken wooden breast (CWB). Compared to normal breast, CWB exhibits distinct quality c…
View article: A new signature associated with anoikis predicts the outcome and immune infiltration in nasopharyngeal carcinoma
A new signature associated with anoikis predicts the outcome and immune infiltration in nasopharyngeal carcinoma Open
View article: ROS-responsive nanoparticles with selenomethionine for ferroptosis modulation in abdominal aortic aneurysm
ROS-responsive nanoparticles with selenomethionine for ferroptosis modulation in abdominal aortic aneurysm Open
Oxidative stress, particularly ROS accumulation, plays a key role in the development of abdominal aortic aneurysm (AAA). Surgical treatments and current drugs for AAA have limitations, including lack of specificity and significant side eff…
View article: Elucidating the Underlying Allelopathy Effects of Euphorbia jolkinii on Arundinella hookeri Using Metabolomics Profiling
Elucidating the Underlying Allelopathy Effects of Euphorbia jolkinii on Arundinella hookeri Using Metabolomics Profiling Open
Euphorbia jolkinii dominates the subalpine meadows in Shangri-La (Southwest China) owing to its potent allelopathic effects. However, the effects underlying its allelopathy require further characterization at the physiological and molecula…
View article: Cooperative integration of spatially resolved multi-omics data with COSMOS
Cooperative integration of spatially resolved multi-omics data with COSMOS Open
View article: Dimensionality reduction for visualizing spatially resolved profiling data using SpaSNE
Dimensionality reduction for visualizing spatially resolved profiling data using SpaSNE Open
Background Spatially resolved profiling technologies to quantify transcriptomes, epigenomes, and proteomes have been emerging as groundbreaking methods for comprehensive molecular characterizations. Dimensionality reduction and visualizati…
View article: Advances in Selenium and Related Compounds Inhibiting Multi-Organ Fibrosis
Advances in Selenium and Related Compounds Inhibiting Multi-Organ Fibrosis Open
Selenium (Se), a critically essential trace element, plays a crucial role in diverse physiological processes within the human body, such as oxidative stress response, inflammation regulation, apoptosis, and lipid metabolism. Organ fibrosis…
View article: Carboxylesterase 4A Inhibits the Malignant Biological Behavior of Nasopharyngeal Carcinoma via the PI3K/AKT Pathway
Carboxylesterase 4A Inhibits the Malignant Biological Behavior of Nasopharyngeal Carcinoma via the PI3K/AKT Pathway Open
Background Carboxylesterase 4A (CES4A) belongs to the member of the carboxylesterase family, yet there has been limited research into its malignant biological behavior in malignant tumors. Here, we aim to investigate the expression, cellul…
View article: Enhancing the Strength and Conductivity of the Cu-Ni-Fe-P-Mg Alloys by Regulation of Nanoscale Precipitation
Enhancing the Strength and Conductivity of the Cu-Ni-Fe-P-Mg Alloys by Regulation of Nanoscale Precipitation Open
View article: Effects of ultrasound-assisted low-salt curing on water retention, tenderness and in vitro digestive characteristics of grass carp (Ctenopharyngodon Idellus)
Effects of ultrasound-assisted low-salt curing on water retention, tenderness and in vitro digestive characteristics of grass carp (Ctenopharyngodon Idellus) Open
The implementation of innovative techniques to achieve low-salt strategies in cured products is a critical issue faced by the food industry. This study aimed to investigate the impact of ultrasound treatment on the quality of the low-salt …
View article: HS-SPME-GC-MS combined with relative odor activity value identify the key aroma components of flowery and fruity aroma in different types of GABA tea
HS-SPME-GC-MS combined with relative odor activity value identify the key aroma components of flowery and fruity aroma in different types of GABA tea Open