Lyska L. Emerson
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Intraprocedural Thromboembolism From Infective Endocarditis With Immediate Endovascular Mechanical Thrombectomy: A Case of Remarkable Timing Open
Infectious intracranial aneurysms and embolic strokes are common neurological complications in patients with infective endocarditis. Diagnostic cerebral angiograms are often performed prior to cardiac valve repair if an infectious intracra…
Persistent symptoms after <span>COVID</span>‐19: an Australian stratified random health survey on long <span>COVID</span> Open
Objective To determine the impact of persistent symptoms after coronavirus disease 2019 (COVID‐19) in an Australian population. Design, setting, participants We conducted a statewide health survey of a stratified random sample of adults wh…
View article: Tenascin-C in the early lung cancer tumor microenvironment promotes progression through integrin αvβ1 and FAK
Tenascin-C in the early lung cancer tumor microenvironment promotes progression through integrin αvβ1 and FAK Open
Pre-cancerous lung lesions are commonly initiated by activating mutations in the RAS pathway, but do not transition to lung adenocarcinomas (LUAD) without additional oncogenic signals. Here, we show that expression of the extracellular mat…
Generation of antigen-specific memory CD4 T cells by heterologous immunization enhances the magnitude of the germinal center response upon influenza infection Open
Current influenza vaccine strategies have yet to overcome significant obstacles, including rapid antigenic drift of seasonal influenza viruses, in generating efficacious long-term humoral immunity. Due to the necessity of germinal center f…
View article: Data from Macrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer
Data from Macrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer Open
Purpose:Clear cell renal cell carcinoma (ccRCC) is frequently associated with inactivation of the von Hippel–Lindau tumor suppressor, resulting in activation of HIF-1α and HIF-2α. The current paradigm, established using mechanistic cell-ba…
Supplementary Methods from Macrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer Open
Additional methods
Supplementary Data from Macrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer Open
Supplemental Tables
Supplementary Data from Macrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer Open
Supplemental Figures
Supplementary Data from Macrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer Open
Supplemental Tables
Supplementary Data from Macrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer Open
Supplemental Figure Legends
Supplementary Data from Macrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer Open
Supplemental Figure Legends
Data from Macrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer Open
Purpose:Clear cell renal cell carcinoma (ccRCC) is frequently associated with inactivation of the von Hippel–Lindau tumor suppressor, resulting in activation of HIF-1α and HIF-2α. The current paradigm, established using mechanistic cell-ba…
Supplementary Methods from Macrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer Open
Additional methods
Supplementary Data from Macrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer Open
Supplemental Figures
Mechanics of lung cancer: A finite element model shows strain amplification during early tumorigenesis Open
Early lung cancer lesions develop within a unique microenvironment that undergoes constant cyclic stretch from respiration. While tumor stiffening is an established driver of tumor progression, the contribution of stress and strain to lung…
Mechanics of lung cancer: A finite element model shows strain amplification during early tumorigenesis Open
Early lung cancer lesions develop within a unique microenvironment that undergoes constant cyclic stretch from respiration. While tumor stiffening is an established driver of tumor progression, the contribution of stress and strain to lung…
Correction: Macrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer Open
In the original version of this article (1), the wrong files were supplied for Figs. 5B and C. The figures and related article text have been corrected in the latest online HTML and PDF versions of this article. The authors regret these er…
1201. Sarcoidosis Candidate Microbes Identified by Next Generation Sequencing Open
Background Sarcoidosis is an autoimmune disease characterized by granulomatous lung disease with very prominent mediastinal adenopathy. Acid-fast bacteria, fungi, and viruses have been considered as possible causes of sarcoidosis. We used …
Macrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer Open
Purpose: Clear cell renal cell carcinoma (ccRCC) is frequently associated with inactivation of the von Hippel–Lindau tumor suppressor, resulting in activation of HIF-1α and HIF-2α. The current paradigm, established using mechanistic cell-b…
Structural variation and its potential impact on genome instability: Novel discoveries in the EGFR landscape by long-read sequencing Open
Structural variation (SV) is typically defined as variation within the human genome that exceeds 50 base pairs (bp). SV may be copy number neutral or it may involve duplications, deletions, and complex rearrangements. Recent studies have s…
Multifocal cavernous hemangioma of the jugular foramen: a rare skull base vascular malformation Open
Jugular foramen cavernous hemangiomas are extremely rare vascular malformations, and, to the best of the authors’ knowledge, their occurrence as multifocal lesions involving both intra- and extracranial compartments has never been reported…
Targeted Intraceptor Nanoparticle for Neovascular Macular Degeneration: Preclinical Dose Optimization and Toxicology Assessment Open
Neovascular age-related macular degeneration (AMD) is treated with anti-VEGF intravitreal injections, which can cause geographic atrophy, infection, and retinal fibrosis. To minimize these toxicities, we developed a nanoparticle delivery s…
Pulmonary Arterial Hypertension in Primary Amyloidosis Open
Amyloidosis involves extravascular deposition of fibrillar proteins within tissues and organs. Primary light chain amyloidosis represents the most common form of systemic amyloidosis involving deposition of monoclonal immunoglobulin light …