Langanani Mbodi
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View article: Surgical Management of Ovarian Masses in Children: A Comparative Analysis by Pediatric Surgeons and Gynecologists at Two Academic Hospitals in Johannesburg
Surgical Management of Ovarian Masses in Children: A Comparative Analysis by Pediatric Surgeons and Gynecologists at Two Academic Hospitals in Johannesburg Open
Background and Objectives Existing literature on ovarian masses necessitating intervention in children by pediatric surgeons and gynecologists in Low‐ and Middle‐Income Countries is sparse and lacks collaborative standardization in managem…
View article: The predictive value of risk assessment models for venous thromboembolism on gynaecological cancer patients
The predictive value of risk assessment models for venous thromboembolism on gynaecological cancer patients Open
Background: Venous thromboembolism (VTE) is a multifactorial disease. There are two main clinical entities that are associated with morbidity and mortality, deep vein thrombosis and pulmonary embolism. Our study aimed to compare the three …
View article: The Exposome Perspective: Environmental and Infectious Agents as Drivers of Cancer Disparities in Low- and Middle-Income Countries
The Exposome Perspective: Environmental and Infectious Agents as Drivers of Cancer Disparities in Low- and Middle-Income Countries Open
Cancer disparities in low- and middle-income countries (LMICs) arise from multifaceted interactions between environmental exposures, infectious agents, and systemic inequities, such as limited access to care. The exposome, a framework enco…
View article: Exploring Water-Soluble South African Tulbaghia violacea Harv Extract as a Therapeutic Approach for Triple-Negative Breast Cancer Metastasis
Exploring Water-Soluble South African Tulbaghia violacea Harv Extract as a Therapeutic Approach for Triple-Negative Breast Cancer Metastasis Open
Triple-negative breast cancer (TNBC) accounts for approximately 20% of all breast cancer cases and is characterized by a lack of estrogen, progesterone, and human epidermal growth factor 2 receptors. Current targeted medicines have been un…
View article: Diagnosis and management of a pelvic solitary fibrous tumor in a postmenopausal woman – a case report
Diagnosis and management of a pelvic solitary fibrous tumor in a postmenopausal woman – a case report Open
Solitary fibrous tumor is very rare; however, the diagnosis should be considered in a postmenopausal woman with solid pelvic mass, normal tumor markers and no ascites.
View article: An audit of adherence to cervical cancer screening guidelines in a tertiary-level HIV clinic
An audit of adherence to cervical cancer screening guidelines in a tertiary-level HIV clinic Open
Background: Cervical cancer is the most common malignancy affecting South African women aged 15–44 years, with a higher prevalence among women living with HIV (WLWH). Despite recommendations for a screening target of 70%, the reported rate…
View article: Trends and Determinants of Operative Vaginal Delivery at Two Academic Hospitals in Johannesburg, South Africa 2005–2019
Trends and Determinants of Operative Vaginal Delivery at Two Academic Hospitals in Johannesburg, South Africa 2005–2019 Open
Operative Vaginal delivery (OVD) can reduce perinatal and maternal morbidity and mortality especially in low resource setting such as South Africa. We evaluated the trends and determinants of OVD rates using join point regression at Charlo…
View article: scoping review of venous thromboembolism and antithrombotic therapy in pregnancy
scoping review of venous thromboembolism and antithrombotic therapy in pregnancy Open
Introduction: Venous thromboembolism (VTE) is a known factor implicated in maternal mortality. Low molecular weight heparin (LMWH) and unfractionated heparin (UFH) are being widely used in cases of VTE. However, the efficiency of both of t…
View article: Genital labial phyllodes tumour recurring during pregnancy - does pregnancy impact recurrence?
Genital labial phyllodes tumour recurring during pregnancy - does pregnancy impact recurrence? Open
Phyllodes tumours (PT) of the vulva are uncommon tumours. The gold standard treatment for these lesions is unknown but is intuitively presumed to be wide local excision. Incomplete resection is associated with recurrence although the time …
View article: The Understanding and Perception of the Menstrual Cup Among Medical Students
The Understanding and Perception of the Menstrual Cup Among Medical Students Open
View article: Impact of cancer therapy on female fertility: a systematic review
Impact of cancer therapy on female fertility: a systematic review Open
Background: Cancers have become highly prevalent in developing countries and Africa is not far from it. The treatment of these cancers increases the risk of infertility in women. Objectives: This review aims to understand the effects of di…
View article: The Innovative use of modified vacuum dressing in post vulvectomy wound
The Innovative use of modified vacuum dressing in post vulvectomy wound Open
We present a case of a patient who had a vulvectomy for large genital warts that could not be primarily closed but was successfully managed with a modified approach of the vacuum dressing until it was closed, allowed to heal, with a cosmet…
View article: Does Repeat Large Loop Excision of the Transformation Zone Achieve a Cure for Histologically Proven Persistent High Grade Squamous Intra-epithelial Lesion at Margins?
Does Repeat Large Loop Excision of the Transformation Zone Achieve a Cure for Histologically Proven Persistent High Grade Squamous Intra-epithelial Lesion at Margins? Open
Cervical cancer is the second most common malignant neoplasm in women world-wide. Cervical Intra-epithelial Neoplasia (CIN) is a precursor lesion of cervical cancer and effective treatment of this lesion by Large Loop Excision …
View article: Phycocyanin / Polysaccharide of Spirulina Platensis for Antitumor Immune Activity
Phycocyanin / Polysaccharide of Spirulina Platensis for Antitumor Immune Activity Open
Phycocyanin (PC) and polysaccharides from spirulina plantensis (PSP) are immune active substances with great anti-tumor potential. The antitumor immune activities of PC and PSP were studied in this paper. The antitumor immune activities of…
View article: Primary ovarian neuroendocrine tumour arising in a benign mature cystic teratoma: a case report and literature review
Primary ovarian neuroendocrine tumour arising in a benign mature cystic teratoma: a case report and literature review Open
Primary ovarian neuroendocrine tumours are very uncommon tumours. Herein, we describe a case of 27-year-old female who presented with abdominal pain and an ovarian mass, for which she underwent a right salpingo-oophorectomy. Histopathologi…
View article: Advanced neuroendocrine carcinoma (Merkel cell carcinoma) of the vulva: a case report and literature review
Advanced neuroendocrine carcinoma (Merkel cell carcinoma) of the vulva: a case report and literature review Open
Neuroendocrine carcinomas (Merkel cell carcinomas) of the vulva are extremely rare tumours, with very few cases reported to date. Herein, a primary neuroendocrine carcinoma (Merkel cell carcinoma) of the vulva is reported. A 34-year-old HI…
View article: A rare case of genital labial phylloides tumour
A rare case of genital labial phylloides tumour Open
Phylloides tumour is an extremely rare fibroepithelial neoplasm, accounting for less than 1% of breast pathologies. We report a rare case of primary phylloides tumour arising within the vulva.
View article: A Stage 1B1 Clear Cell Cervical Cancer Patient who fell Pregnant whilst Awaiting Fertility Sparring Surgery Managed with Neoadjuvant Chemotherapy to Arrest Disease Progression
A Stage 1B1 Clear Cell Cervical Cancer Patient who fell Pregnant whilst Awaiting Fertility Sparring Surgery Managed with Neoadjuvant Chemotherapy to Arrest Disease Progression Open
We present a case of a 25 years old woman who presented to the gynaecological oncology unit before pregnancy with a histological and clinical diagnosis of cervical squamous cell carcinoma stage 1B1. She desired fertility and hence an elect…
View article: A rare case of concomitant bilateral nipple and vulval condyloma accuminatum
A rare case of concomitant bilateral nipple and vulval condyloma accuminatum Open
In this case study, we have presented a rare case of concomitant human papillomavirus condylomata lesions of both breast nipples and giant vulval warts in an HIV-positive woman on antiretroviral therapy. The woman underwent successful surg…