Langlang Xie
YOU?
Author Swipe
View article: PDGFC facilitates enzalutamide resistance in prostate cancer through activation of the Rap1-MAPK pathway
PDGFC facilitates enzalutamide resistance in prostate cancer through activation of the Rap1-MAPK pathway Open
View article: The CTSZ-TRA2A-IL32 axis defines a targetable macrophage-dependent pathway in metastatic prostate cancer
The CTSZ-TRA2A-IL32 axis defines a targetable macrophage-dependent pathway in metastatic prostate cancer Open
View article: An orally-administered nanotherapeutics with gold nanospheres supplying for rheumatoid arthritis therapy by re-shaping gut microbial tryptophan metabolism
An orally-administered nanotherapeutics with gold nanospheres supplying for rheumatoid arthritis therapy by re-shaping gut microbial tryptophan metabolism Open
View article: Aberrant Tryptophan Metabolism Manipulates Osteochondral Homeostasis
Aberrant Tryptophan Metabolism Manipulates Osteochondral Homeostasis Open
Tryptophan (Trp), an essential amino acid, performs as a precursor for synthesizing various bioactive molecules primarily metabolized through the kynurenine (Kyn), serotonin, and indole pathways. The diverse metabolites were deeply implica…
View article: Silencing SPP1 in M2 macrophages inhibits the progression of castration-resistant prostate cancer via the MMP9/TGFβ1 axis
Silencing SPP1 in M2 macrophages inhibits the progression of castration-resistant prostate cancer via the MMP9/TGFβ1 axis Open
We have found that the high expression of SPP1 in M2 macrophages promotes the progression of CRPC through cell-cell interactions. These findings can contribute to the development of novel therapeutic approaches for combating this deadly di…