Lanhua Wu
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View article: Ginsenoside Rg1 promotes the efficacy of human amnion-derived mesenchymal stem cells in alleviating chemotherapy-induced premature ovarian insufficiency in rats
Ginsenoside Rg1 promotes the efficacy of human amnion-derived mesenchymal stem cells in alleviating chemotherapy-induced premature ovarian insufficiency in rats Open
Rg1 may promote the efficacy of hAD-MSC transplantation in alleviating chemotherapy-induced POI in rats. Rg1 might be a novel adjuvant drug to promote the efficacy of MSCs in the treatment of chemotherapy-induced POI.
View article: Genome-wide association study and transcriptome analysis reveal candidate genes related to drought stress in the germination stage of soybean
Genome-wide association study and transcriptome analysis reveal candidate genes related to drought stress in the germination stage of soybean Open
Drought is the major abiotic stress threatening soybean production globally. However, the genetic basis of soybean drought resistance at the germination stage remains largely unknown. In this study, the drought-tolerance phenotypes of a di…
View article: BHLHE40-mediated upregulation of CAV1 decreases the radiosensitivity of nasopharyngeal carcinoma
BHLHE40-mediated upregulation of CAV1 decreases the radiosensitivity of nasopharyngeal carcinoma Open
This study reveals that BHLHE40 reduces NPC radiosensitivity by transcriptionally activating CAV1, which in turn activates the Akt pathway. In addition, CAV1-containing exosomes secreted by radioresistant NPC cells promote angiogenesis, fu…
View article: Evaluating H2BC9 as a potential diagnostic and prognostic biomarker in head and neck squamous cell carcinoma
Evaluating H2BC9 as a potential diagnostic and prognostic biomarker in head and neck squamous cell carcinoma Open
We demonstrated that H2BC9 expression may be associated with HNSCC development and prognosis. These findings may provide a potential therapeutic target for HNSCC.
View article: Combined BSA-Seq and RNA-Seq Analysis to Identify Candidate Genes Associated with Aluminum Toxicity in Rapeseed (Brassica napus L.)
Combined BSA-Seq and RNA-Seq Analysis to Identify Candidate Genes Associated with Aluminum Toxicity in Rapeseed (Brassica napus L.) Open
Exchangeable aluminum (Al) ions released from acidic soils with pH < 5.5 inhibit root elongation of crops, ultimately leading to yield reduced. It is necessary to identify the quantitative trait locus (QTLs) and candidate genes that confer…
View article: Investigation of miR-15b-5p expression and role in head and neck squamous cell carcinoma based on meta-analysis and bioinformatics analysis
Investigation of miR-15b-5p expression and role in head and neck squamous cell carcinoma based on meta-analysis and bioinformatics analysis Open
Background: In the current study, miR-15b-5p expression and role in HNSCC remains indistinct. The aim of this study was to investigate the expression and role of miR-15b-5p in HNSCC. Methods: The data obtained from Gene Expression Omnibus …
View article: Biological function analysis of miR-15b-5p promoting head and neck tumor development by targeting UGT1A7
Biological function analysis of miR-15b-5p promoting head and neck tumor development by targeting UGT1A7 Open
Background: Head and neck squamous cell carcinoma (HNSCC) is a common malignant tumor. MicroRNA function and expression abnormalities are closely related to tumor development. Nevertheless, the role of miR-15b-5p in HNSCC remains indistinc…