Lara Busby
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View article: Ectomesenchymal identity emerges via relief of <i>Twist1</i> transcript destabilization
Ectomesenchymal identity emerges via relief of <i>Twist1</i> transcript destabilization Open
During vertebrate development, cranial neural crest cells (CNCCs) differentiate into a variety of derivatives, including ectodermal cell types (neurons, glia, and pigment cells) as well as a suite of derivatives that are classically associ…
View article: Author response: Intrinsic and extrinsic cues time somite progenitor contribution to the vertebrate primary body axis
Author response: Intrinsic and extrinsic cues time somite progenitor contribution to the vertebrate primary body axis Open
View article: A population intrinsic timer controls <i>Hox</i> gene expression and cell dispersion during progenitor addition to the body axis
A population intrinsic timer controls <i>Hox</i> gene expression and cell dispersion during progenitor addition to the body axis Open
During embryonic development, the timing of events at the cellular level must be coordinated across multiple length scales to ensure the formation of a well-proportioned body plan. This is clear during somitogenesis, where the progenitors …
View article: Symmetry breaking in the female germline cyst
Symmetry breaking in the female germline cyst Open
Specifying one oocyte from many In many animals, only one cell from a cyst of germ cells is selected to become the oocyte. Using fruit flies as a model, Nashchekin et al . identified the microtubule minus end-binding protein Patronin/CAMSA…
View article: Symmetry breaking in the female germline cyst
Symmetry breaking in the female germline cyst Open
In mammals and flies, only a limited number of cells in a multicellular female germline cyst become oocytes, but how the oocyte is selected is unknown. Here we show that the microtubule minus end-stabilizing protein, Patronin/CAMSAP marks …
View article: Tissue Tectonics and the Multi-Scale Regulation of Developmental Timing
Tissue Tectonics and the Multi-Scale Regulation of Developmental Timing Open
Development encompasses processes that occur at multiple length-scales, includ- ing gene regulatory interactions, cell movements and reorganisation, cell signalling and growth. It is essential that the timing of events in all of these diff…
View article: Hybridization Chain Reaction for Quantitative and Multiplex Imaging of Gene Expression in Amphioxus Embryos and Adult Tissues
Hybridization Chain Reaction for Quantitative and Multiplex Imaging of Gene Expression in Amphioxus Embryos and Adult Tissues Open
View article: A positional information gradient of sonic hedgehog is required for flight feather formation in avian wings
A positional information gradient of sonic hedgehog is required for flight feather formation in avian wings Open
Flight is a triumph of evolution that enabled the radiation and success of birds. A crucial step was the development of forelimb flight feathers that may have evolved for courtship or territorial displays in ancestral theropod dinosaurs. C…