Lara Hartjes
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View article: Keratinocyte-intrinsic BCL10/MALT1 activity initiates and amplifies psoriasiform skin inflammation
Keratinocyte-intrinsic BCL10/MALT1 activity initiates and amplifies psoriasiform skin inflammation Open
BCL10/MALT1 signaling in keratinocytes is altered in human sporadic psoriasis and is a critical initiator and amplifier of skin inflammation in mouse models.
View article: Bcl10-controlled Malt1 paracaspase activity is key for the immune suppressive function of regulatory T cells
Bcl10-controlled Malt1 paracaspase activity is key for the immune suppressive function of regulatory T cells Open
View article: CARD9 Signaling in Intestinal Immune Homeostasis and Oncogenesis
CARD9 Signaling in Intestinal Immune Homeostasis and Oncogenesis Open
Intestinal homeostasis requires a balanced interaction between the host innate immune system and the gut microbiota. A dysregulation of this interdependency can result in inflammatory bowel diseases (IBDs), and this dysregulation is a key …
View article: The Lack of WIP Binding to Actin Results in Impaired B Cell Migration and Altered Humoral Immune Responses
The Lack of WIP Binding to Actin Results in Impaired B Cell Migration and Altered Humoral Immune Responses Open
View article: K + Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria
K + Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria Open