S. Larry Goldenberg
YOU?
Author Swipe
View article: A modular method for rapidly prototyping targeted gas vesicle protein nanoparticles
A modular method for rapidly prototyping targeted gas vesicle protein nanoparticles Open
Gas vesicles (GVs) are air-filled protein nanoparticles which are proving to be useful in a number of biomedical applications. We hypothesized that it could be possible to develop a modular method for creating rapidly prototyped GVs by mod…
View article: Prostate Cancer Risk Stratification by Digital Histopathology and Deep Learning
Prostate Cancer Risk Stratification by Digital Histopathology and Deep Learning Open
PURPOSE Prostate cancer (PCa) represents a highly heterogeneous disease that requires tools to assess oncologic risk and guide patient management and treatment planning. Current models are based on various clinical and pathologic parameter…
View article: Quasi-Real Time Multi-Frequency 3D Shear Wave Absolute Vibro-Elastography (S-WAVE) System for Prostate
Quasi-Real Time Multi-Frequency 3D Shear Wave Absolute Vibro-Elastography (S-WAVE) System for Prostate Open
This article describes a novel quasi-real time system for quantitative and volumetric measurement of tissue elasticity in the prostate. Tissue elasticity is computed by using a local frequency estimator to measure the three dimensional loc…
View article: Aquablation therapy in large prostates (80–150 cc) for lower urinary tract symptoms due to benign prostatic hyperplasia: WATER II 3‐year trial results
Aquablation therapy in large prostates (80–150 cc) for lower urinary tract symptoms due to benign prostatic hyperplasia: WATER II 3‐year trial results Open
Objective The objective of this study is to determine if Aquablation therapy can maintain its effectiveness in treating men with lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) with large‐volume (80–150 cc) pr…
View article: Factors Associated with Time to Conversion from Active Surveillance to Treatment for Prostate Cancer in a Multi-Institutional Cohort
Factors Associated with Time to Conversion from Active Surveillance to Treatment for Prostate Cancer in a Multi-Institutional Cohort Open
A shorter time to conversion from active surveillance to treatment was associated with higher-risk clinicopathological tumor features. Furthermore, patients with high-volume GG1 tumors behaved similarly to those with intermediate and high-…
View article: Genetic Factors Associated with Prostate Cancer Conversion from Active Surveillance to Treatment
Genetic Factors Associated with Prostate Cancer Conversion from Active Surveillance to Treatment Open
Men diagnosed with low-risk prostate cancer (PC) are increasingly electing active surveillance (AS) as their initial management strategy. While this may reduce the side effects of treatment for prostate cancer, many men on AS eventually co…
View article: Promoting Men’s Health With the “Don’t Change Much” e-Program
Promoting Men’s Health With the “Don’t Change Much” e-Program Open
Men’s e-health promotion programs can offer end-user anonymity and autonomy that provide avenues for supporting positive health behavior change. The twofold purpose of the current study was to use a benchmark cohort as a reference group to…
View article: National Classification of Diet and Exercise Behaviours: How Healthy are Canadian Men?
National Classification of Diet and Exercise Behaviours: How Healthy are Canadian Men? Open
Introduction: Unhealthy behaviours, including poor diet and lack of physical inactivity, are risk factors for premature mortality in men worldwide. Identifying disparities and inequalities regarding these habits in Canadian men may allow f…
View article: Testosterone therapy: Prescribing and monitoring patterns of practice in British Columbia
Testosterone therapy: Prescribing and monitoring patterns of practice in British Columbia Open
Introduction: Guidelines recommend that testosterone therapy (TTh) be restricted to men with a biochemical diagnosis of hypogonadism, and that therapeutic responses be titrated within the normal range.
Methods: Using four provincial longi…
View article: Clinical pearls to managing men’s health conditions during the COVID-19 pandemic
Clinical pearls to managing men’s health conditions during the COVID-19 pandemic Open
In late 2019, a novel coronavirus (Sars-CoV-2) was identified in Wuhan, China.1 Subsequently, the rapid spread of the coronavirus disease 2019 (COVID-19) around the world has resulted in the declaration of a pandemic by the World Health Or…
View article: Mapping Canadian Men’s Recent and Intended Health Behavior Changes Through the Don’t Change Much Electronic Health Program
Mapping Canadian Men’s Recent and Intended Health Behavior Changes Through the Don’t Change Much Electronic Health Program Open
Background Although evaluation studies confirm the strong potential of men’s electronic health (eHealth) programs, there have been calls to more fully understand acceptability, engagement, and behavior change to guide future work. Relatedl…
View article: Mapping Canadian Men’s Recent and Intended Health Behavior Changes Through the Don’t Change Much Electronic Health Program (Preprint)
Mapping Canadian Men’s Recent and Intended Health Behavior Changes Through the Don’t Change Much Electronic Health Program (Preprint) Open
BACKGROUND Although evaluation studies confirm the strong potential of men’s electronic health (eHealth) programs, there have been calls to more fully understand acceptability, engagement, and behavior change to guide future work. Related…
View article: A Prospective Study on <sup>18</sup>F-DCFPyL PSMA PET/CT Imaging in Biochemical Recurrence of Prostate Cancer
A Prospective Study on <sup>18</sup>F-DCFPyL PSMA PET/CT Imaging in Biochemical Recurrence of Prostate Cancer Open
18F-DCFPyL (2-(3-{1-carboxy-5-[(6-18F-fluoro-pyridine-3-carbonyl)-amino]-pentyl}-ureido)-pentanedioic acid), a prostate-specific membrane antigen-targeting radiotracer, has shown promise as a prostate cancer imaging radiotracer. We evaluat…
View article: Comparison of Artificial Intelligence Techniques to Evaluate Performance of a Classifier for Automatic Grading of Prostate Cancer From Digitized Histopathologic Images
Comparison of Artificial Intelligence Techniques to Evaluate Performance of a Classifier for Automatic Grading of Prostate Cancer From Digitized Histopathologic Images Open
Results of this study suggest that in prostate cancer classification from histopathologic images, patch-wise CV and single-expert training and evaluation may lead to a biased estimation of classifier's performance. To allow reproducibility…
View article: Predictors of Unhealthy Alcohol Consumption Behavior in Canadian Men
Predictors of Unhealthy Alcohol Consumption Behavior in Canadian Men Open
Aims Men are more likely to engage in alcohol consumption, which can have long-term consequences. The objective of our study was to sample Canadian men to determine predictors of hazardous alcohol hazardous as well as predictors for change…
View article: Aquablation among novice users in Canada: A WATER II subpopulation analysis
Aquablation among novice users in Canada: A WATER II subpopulation analysis Open
Introduction: Surgical management options for lower urinary tract symptoms/benign prostatic hyperplasia (LUTS/BPH) associated with prostates of small to moderate volume (80 cc), many of these options are neither safe nor effective. Recentl…
View article: Unhealthy Behaviors Among Canadian Men Are Predictors of Comorbidities: Implications for Clinical Practice
Unhealthy Behaviors Among Canadian Men Are Predictors of Comorbidities: Implications for Clinical Practice Open
Men’s poor health behaviors are an increasingly prevalent issue with long-term consequences. This study broadly samples Canadian men to obtain information regarding health behaviors as a predictor of downstream medical comorbidities. A sur…
View article: Supplementary data: Prostate-specific antigen testing for prostate cancer screening: A national survey of Canadian primary care physicians’ opinions and practices
Supplementary data: Prostate-specific antigen testing for prostate cancer screening: A national survey of Canadian primary care physicians’ opinions and practices Open
N/A
View article: Prostate-specific antigen testing for prostate cancer screening: A national survey of Canadian primary care physicians’ opinions and practices
Prostate-specific antigen testing for prostate cancer screening: A national survey of Canadian primary care physicians’ opinions and practices Open
Introduction: In 2014, the Canadian Task Force on Preventive Health Care (CTFPHC) recommended against routine prostate cancer screening with the prostate-specific antigen (PSA) blood test.1 We surveyed Canadian primary care physicians (PCP…
View article: The HAT TRICK programme for improving physical activity, healthy eating and connectedness among overweight, inactive men: study protocol of a pragmatic feasibility trial
The HAT TRICK programme for improving physical activity, healthy eating and connectedness among overweight, inactive men: study protocol of a pragmatic feasibility trial Open
Introduction Physical activity, healthy eating and maintaining a healthy weight are associated with reduced risk of cardiovascular disease, type 2 diabetes and cancer and with improved mental health. Despite these benefits, many men do not…
View article: Evolving attitudes toward robotic surgery among Canadian urology residents
Evolving attitudes toward robotic surgery among Canadian urology residents Open
Introduction: Robotic-assisted laparoscopic surgery (RAS) has not been adopted as rapidly or widely in Canada as in the U.S. In 2011, Canadian urology residents felt that RAS represented an expanding field that could potentially negatively…
View article: Luminal Water Imaging: A New MR Imaging T2 Mapping Technique for Prostate Cancer Diagnosis
Luminal Water Imaging: A New MR Imaging T2 Mapping Technique for Prostate Cancer Diagnosis Open
Purpose To assess the feasibility of luminal water imaging, a quantitative T2-based magnetic resonance (MR) imaging technique, for the detection and grading of prostate cancer (PCa). Materials and Methods Eighteen patients with biopsy-prov…
View article: MR measurement of luminal water in prostate gland: Quantitative correlation between MRI and histology
MR measurement of luminal water in prostate gland: Quantitative correlation between MRI and histology Open
Purpose To determine the relationship between parameters measured from luminal water imaging (LWI), a new magnetic resonance imaging (MRI) T 2 mapping technique, and the corresponding tissue composition in prostate. Materials and Methods I…
View article: DEVELOPMENT AND CASE-CONTROL VALIDATION OF THE CANADIAN MEN’S HEALTH FOUNDATION’S SELF RISK-ASSESSMENT TOOL: “YOU CHECK”
DEVELOPMENT AND CASE-CONTROL VALIDATION OF THE CANADIAN MEN’S HEALTH FOUNDATION’S SELF RISK-ASSESSMENT TOOL: “YOU CHECK” Open
Background and Objective: To facilitate the engagement of men in the evaluation of their own health status and risk of disease, we have developed and validated the Canadian Men’s Health Foundation’s self-risk assessment tool (“You Check”).…
View article: Testosterone Therapy in Patients with Treated and Untreated Prostate Cancer: Impact on Oncologic Outcomes
Testosterone Therapy in Patients with Treated and Untreated Prostate Cancer: Impact on Oncologic Outcomes Open
In the absence of randomized, placebo controlled trials our study supports the hypothesis that testosterone therapy may be oncologically safe in hypogonadal men after definitive treatment or in those on active surveillance for prostate can…
View article: MP37-18 EVALUATING PATTERNS OF TESTOSTERONE PRESCRIPTION AMONG 40,878 USERS IN BRITISH COLUMBIA BETWEEN 1997-2013
MP37-18 EVALUATING PATTERNS OF TESTOSTERONE PRESCRIPTION AMONG 40,878 USERS IN BRITISH COLUMBIA BETWEEN 1997-2013 Open
You have accessJournal of UrologyGeneral & Epidemiological Trends & Socioeconomics: Practice Patterns, Quality of Life and Shared Decision Making IV1 Apr 2016MP37-18 EVALUATING PATTERNS OF TESTOSTERONE PRESCRIPTION AMONG 40,878 USERS IN BR…
View article: ‘Should I get a PSA test?’ – the question is not that simple
‘Should I get a PSA test?’ – the question is not that simple Open
PSA screening for prostate cancer is a controversial issue around the world. In this article the authors describe the situation in North America where screening is not being advised. They argue that patients should be tested and that men w…
View article: Erectile Dysfunction and Undiagnosed Diabetes, Hypertension, and Hypercholesterolemia
Erectile Dysfunction and Undiagnosed Diabetes, Hypertension, and Hypercholesterolemia Open
Our results underscore the importance of erectile dysfunction as a marker of undiagnosed diabetes. Erectile dysfunction should be a trigger to initiate diabetes screening, particularly among middle-aged men.