Lars Haag
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View article: Nanodiamonds Interact with Primary Human Macrophages and Dendritic Cells Evoking a Vigorous Interferon Response
Nanodiamonds Interact with Primary Human Macrophages and Dendritic Cells Evoking a Vigorous Interferon Response Open
Nanodiamonds (NDs) display several attractive features rendering them useful for medical applications such as drug delivery. However, the interactions between NDs and the immune system remain poorly understood. Here, we investigated amino-…
View article: Polymorphic parasitic larvae cooperate to build swimming colonies luring hosts
Polymorphic parasitic larvae cooperate to build swimming colonies luring hosts Open
Parasites have evolved a variety of astonishing strategies to survive within their hosts, yet the most challenging event in their personal chronicles is the passage from one host to another. It becomes even more complex when a parasite nee…
View article: Exploiting Mass Spectrometry to Unlock the Mechanism of Nanoparticle-Induced Inflammasome Activation
Exploiting Mass Spectrometry to Unlock the Mechanism of Nanoparticle-Induced Inflammasome Activation Open
Nanoparticles (NPs) elicit sterile inflammation, but the underlying signaling pathways are poorly understood. Here, we report that human monocytes are particularly vulnerable to amorphous silica NPs, as evidenced by single-cell-based analy…
View article: Periprosthetic joint infection after total hip arthroplasty induces histological degeneration of the gluteus medius tendon
Periprosthetic joint infection after total hip arthroplasty induces histological degeneration of the gluteus medius tendon Open
Aims A revision for periprosthetic joint infection (PJI) in total hip arthroplasty (THA) has a major effect on the patient’s quality of life, including walking capacity. The objective of this case control study was to investigate the histo…
View article: Toxicity of stainless and mild steel particles generated from gas–metal arc welding in primary human small airway epithelial cells
Toxicity of stainless and mild steel particles generated from gas–metal arc welding in primary human small airway epithelial cells Open
Welding fumes induce lung toxicity and are carcinogenic to humans but the molecular mechanisms have yet to be clarified. The aim of this study was to evaluate the toxicity of stainless and mild steel particles generated via gas–metal arc w…
View article: Additional file 1 of Histological and ultrastructural degenerative findings in the gluteus medius tendon after hip arthroplasty
Additional file 1 of Histological and ultrastructural degenerative findings in the gluteus medius tendon after hip arthroplasty Open
Additional file 1. Histology original data
View article: Additional file 2 of Histological and ultrastructural degenerative findings in the gluteus medius tendon after hip arthroplasty
Additional file 2 of Histological and ultrastructural degenerative findings in the gluteus medius tendon after hip arthroplasty Open
Additional file 2. Electron microscopy original data.
View article: Pulmonary stromal expansion and intra-alveolar coagulation are primary causes of Covid-19 death
Pulmonary stromal expansion and intra-alveolar coagulation are primary causes of Covid-19 death Open
Summary Most Covid-19 victims are old and die from unrelated causes. Here we present t welve complete autopsies, including two rapid autopsies of young patients where the cause of death was Covid-19 ARDS. The main virus induced pathology w…
View article: Development of a Multivalent Kunjin Virus Reporter Virus-Like Particle System Inducing Seroconversion for Ebola and West Nile Virus Proteins in Mice
Development of a Multivalent Kunjin Virus Reporter Virus-Like Particle System Inducing Seroconversion for Ebola and West Nile Virus Proteins in Mice Open
Kunjin virus (KUNV) is an attenuated strain of the severe neurotropic West Nile virus (WNV). The virus has a single-strand positive-sense RNA genome that encodes a polyprotein. Following gene expression, the polyprotein is cleaved into str…