Lars Husmann
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View article: Whole-body dynamic FDG-PET/CT parametric imaging in alveolar echinococcosis
Whole-body dynamic FDG-PET/CT parametric imaging in alveolar echinococcosis Open
Objective To determine the role of whole-body dynamic (WBD)/Patlak parametric 18 F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) in patients with alveolar echinococcosis (AE). This technique allows sepa…
View article: Whole-body dynamic FDG-PET/CT Parametric Imaging in Alveolar Echinococcosis
Whole-body dynamic FDG-PET/CT Parametric Imaging in Alveolar Echinococcosis Open
Objective To determine the role of whole-body dynamic (WBD) / Patlak parametric 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) in patients with alveolar echinococcosis (AE). This technique allows sep…
View article: PET/MR for predicting extranodal extension of head and neck cancer
PET/MR for predicting extranodal extension of head and neck cancer Open
Purpose To analyze the diagnostic accuracy of multiparametric FDG-PET/MR in identifying pathologic extranodal extension (pENE) of lymph node metastases (LNM) in head and neck squamous cell carcinoma (HNSCC) patients. Methods and materials …
View article: Management of biliary obstruction in patients with newly diagnosed alveolar echinococcosis: a Swiss retrospective cohort study
Management of biliary obstruction in patients with newly diagnosed alveolar echinococcosis: a Swiss retrospective cohort study Open
BACKGROUND AND STUDY AIMS: Alveolar echinococcosis, an orphan zoonosis affecting the liver, is of increasing concern worldwide. Most symptomatic cases present at an advanced and inoperable stage, sometimes with biliary obstruction promptin…
View article: Imaging characteristics and diagnostic accuracy of FDG-PET/CT, contrast enhanced CT and combined imaging in patients with suspected mycotic or inflammatory abdominal aortic aneurysms
Imaging characteristics and diagnostic accuracy of FDG-PET/CT, contrast enhanced CT and combined imaging in patients with suspected mycotic or inflammatory abdominal aortic aneurysms Open
Purpose To evaluate the diagnostic accuracy and specific imaging characteristics of positron emission tomography/computed tomography with 18F-fluorodeoxyglucose (PET/CT), contrast enhanced CT (CE-CT), and a combined imaging approach (CE-PE…
View article: Follow-up PET/CT of alveolar echinococcosis: Comparison of metabolic activity and immunodiagnostic testing
Follow-up PET/CT of alveolar echinococcosis: Comparison of metabolic activity and immunodiagnostic testing Open
Purpose To investigate the potential role of follow-up 18 F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) in therapy control of inoperable patients with alveolar echinococcosis. Materials and methods In…
View article: Characteristics and Clinical Course of Alveolar Echinococcosis in Patients with Immunosuppression-Associated Conditions: A Retrospective Cohort Study
Characteristics and Clinical Course of Alveolar Echinococcosis in Patients with Immunosuppression-Associated Conditions: A Retrospective Cohort Study Open
Objectives: Since the change in the millennium, an increase in cases of alveolar echinococcosis (AE) has been observed in endemic European countries. Previous studies indicate that a significant proportion of the new AE cases have an immun…
View article: Staging of Alveolar Echinococcosis with PET/CT: Prediction of Benzimidazole Therapy Duration in Inoperable Patients
Staging of Alveolar Echinococcosis with PET/CT: Prediction of Benzimidazole Therapy Duration in Inoperable Patients Open
Alveolar echinococcosis is a rare parasitic disease, most frequently affecting the liver, as a slow-growing tumor-like lesion. If inoperable, long-term benzimidazole therapy is required, which is associated with high healthcare costs and o…
View article: BSREM for Brain Metastasis Detection with 18F-FDG-PET/CT in Lung Cancer Patients
BSREM for Brain Metastasis Detection with 18F-FDG-PET/CT in Lung Cancer Patients Open
The aim of the study was to analyze the use of block sequential regularized expectation maximization (BSREM) with different β -values for the detection of brain metastases in digital fluorine-18 labeled 2-deoxy-2-fluoro-D-glucose (18F-FDG)…
View article: Evaluation of a structured treatment discontinuation in patients with inoperable alveolar echinococcosis on long-term benzimidazole therapy: A retrospective cohort study
Evaluation of a structured treatment discontinuation in patients with inoperable alveolar echinococcosis on long-term benzimidazole therapy: A retrospective cohort study Open
Objectives Alveolar echinococcosis (AE) is an orphan zoonosis of increasing concern in endemic areas, including Europe. It frequently presents in an advanced, inoperable stage, that requires life-long parasitostatic benzimidazole therapy. …
View article: Vascular graft infections
Vascular graft infections Open
Vascular graft infections are rare complications after surgical and endovascular treatment of aortic diseases. This condition is characterized by complexity in diagnosis and medico-surgical management. Moreover, even if properly treated, m…
View article: Impact of PET/CT among patients with suspected mycotic aortic aneurysms
Impact of PET/CT among patients with suspected mycotic aortic aneurysms Open
Purpose To determine the impact of 18 F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) on clinical management in patients with suspected mycotic aortic aneurysms (MAA). Materials and methods For this obs…
View article: Clinical evaluation of data-driven respiratory gating for PET/CT in an oncological cohort of 149 patients: impact on image quality and patient management
Clinical evaluation of data-driven respiratory gating for PET/CT in an oncological cohort of 149 patients: impact on image quality and patient management Open
Objectives: To evaluate the impact of fully automatic motion correction by data-driven respiratory gating (DDG) on positron emission tomography (PET) image quality, lesion detection and patient management. Materials and Methods: A total of…
View article: <scp>Whole‐body</scp> hybrid positron emission tomography imaging yields clinically relevant information in the staging and restaging of sinonasal tumors
<span>Whole‐body</span> hybrid positron emission tomography imaging yields clinically relevant information in the staging and restaging of sinonasal tumors Open
Background Whole‐body hybrid positron emission tomography (PET) imaging is increasingly used for sinonasal tumors. However, only empirical data exist on the additional, clinically relevant information derived from these techniques. Methods…
View article: Malignancy Rate of Indeterminate Findings on FDG-PET/CT in Cutaneous Melanoma Patients
Malignancy Rate of Indeterminate Findings on FDG-PET/CT in Cutaneous Melanoma Patients Open
Background: The use of 18F-2-Fluor-2-desoxy-D-glucose Positron Emission Tomography/Computed Tomography FDG-PET/CT in clinical routine for staging, treatment response monitoring and post treatment surveillance in metastatic melanoma patient…
View article: Improved detection of in-transit metastases of malignant melanoma with BSREM reconstruction in digital [18F]FDG PET/CT
Improved detection of in-transit metastases of malignant melanoma with BSREM reconstruction in digital [18F]FDG PET/CT Open
Objectives To compare block sequential regularized expectation maximization (BSREM) and ordered subset expectation maximization (OSEM) for the detection of in-transit metastasis (ITM) of malignant melanoma in digital [ 18 F]FDG PET/CT. Met…
View article: Open wounds and rifampicin therapy are associated with rifampicin resistance among staphylococcal vascular graft/endograft infections
Open wounds and rifampicin therapy are associated with rifampicin resistance among staphylococcal vascular graft/endograft infections Open
Background Optimal timing for rifampicin combination therapy in patients with staphylococcal vascular graft/endograft infection (S-VGEI) is unknown. Experts recommend adding rifampicin after lowering bacterial load by surgery and wound clo…
View article: Therapy Control in a Patient With an Inflammatory Abdominal Aneurysm
Therapy Control in a Patient With an Inflammatory Abdominal Aneurysm Open
We present a case of inflammatory abdominal arterial aneurysms, which demonstrates the potential usefulness of PET/CT with 18 F-FDG in long-term monitoring of this disease, but also demonstrates potential pitfalls in abdominal arterial ane…
View article: Immunohistochemical PSMA expression patterns of primary prostate cancer tissue are associated with the detection rate of biochemical recurrence with <sup>68</sup>Ga-PSMA-11-PET
Immunohistochemical PSMA expression patterns of primary prostate cancer tissue are associated with the detection rate of biochemical recurrence with <sup>68</sup>Ga-PSMA-11-PET Open
Prostate-specific membrane antigen (PSMA) targeted PET has a high detection rate for biochemical recurrence (BCR) of prostate cancer (PCa). Nevertheless, even at high prostate-specific antigen (PSA) levels (> 3 ng/ml), a relevant number of…
View article: Aortic Endograft Infection with <i>Mycobacterium chimaera</i> and <i>Granulicatella adiacens</i>, Switzerland, 2014
Aortic Endograft Infection with <i>Mycobacterium chimaera</i> and <i>Granulicatella adiacens</i>, Switzerland, 2014 Open
We describe an aortic endograft infection caused by Mycobacterium chimaera and Granulicatella adiacens, successfully treated with prolonged antimicrobial drug therapy after complete explantation of the infected endoprosthesis and extra-ana…
View article: <sup>18</sup>F-FDG PET/CT of Non–Small Cell Lung Carcinoma Under Neoadjuvant Chemotherapy: Background-Based Adaptive-Volume Metrics Outperform TLG and MTV in Predicting Histopathologic Response
<sup>18</sup>F-FDG PET/CT of Non–Small Cell Lung Carcinoma Under Neoadjuvant Chemotherapy: Background-Based Adaptive-Volume Metrics Outperform TLG and MTV in Predicting Histopathologic Response Open
PET volume metrics based on background-adaptive methods correlate better with histopathologic tumor regression score in NSCLC patients under neoadjuvant chemotherapy than algorithms and methods using a fixed threshold (42% SUVmax).