Lars Muckli
YOU?
Author Swipe
View article: Advancing the science of consciousness: From ethics to clinical care
Advancing the science of consciousness: From ethics to clinical care Open
Significant advances in the scientific investigation of the neurobiology of consciousness have been slow to be translated into clinical settings, limited by a lack of generally agreed working definition (e.g., what is consciousness?) and m…
View article: The effects of action-based predictions in early visual cortex
The effects of action-based predictions in early visual cortex Open
During voluntary movement, predictions about the sensory consequences of an action typically result in reduced sensory sensitivity. The forward model theory proposes that this reduced sensitivity is due to neural suppression or cancellatio…
View article: Perceptual Priors Update Contextual Feedback Processing in V1
Perceptual Priors Update Contextual Feedback Processing in V1 Open
Contextual information and prior knowledge facilitate perceptual processing, improving our recognition of even distorted or obstructed visual inputs. As a result, neuronal processing elicited by identical sensory inputs varies depending on…
View article: Protocol for investigating the warping of spatial experience across the blind spot to contrast predictions of the Integrated Information Theory and Predictive Processing accounts of consciousness
Protocol for investigating the warping of spatial experience across the blind spot to contrast predictions of the Integrated Information Theory and Predictive Processing accounts of consciousness Open
We investigate the subjective experience of space around the visual blind spot area, the cortical representation of which is missing feedforward connectivity from one eye. We performed these experiments as part of an adversarial collaborat…
View article: Protocol for investigating the warping of spatial experience across the blind spot to contrast predictions of the Integrated Information Theory and Predictive Processing accounts of consciousness
Protocol for investigating the warping of spatial experience across the blind spot to contrast predictions of the Integrated Information Theory and Predictive Processing accounts of consciousness Open
We investigate the subjective experience of space around the visual blind spot area, the cortical representation of which is missing feedforward connectivity from one eye. We performed these experiments as part of an adversarial collaborat…
View article: Priors, evidence, and memory: Dynamics of predictive processing in a hierarchical visual system
Priors, evidence, and memory: Dynamics of predictive processing in a hierarchical visual system Open
No abstract available.
View article: Revealing layer-specific cortical activity in human M1 using high-resolution line-scanning fMRI
Revealing layer-specific cortical activity in human M1 using high-resolution line-scanning fMRI Open
In recent years, ultra-high field functional MRI has allowed researchers to study cortical activity at high spatiotemporal resolution. Advancements in technology have made it possible to perform fMRI of cortical laminae, which is crucial f…
View article: Retinotopic biases in contextual feedback signals to V1 for object and scene processing
Retinotopic biases in contextual feedback signals to V1 for object and scene processing Open
Identifying the objects embedded in natural scenes relies on recurrent processing between lower and higher visual areas. How is cortical feedback information related to objects and scenes organised in lower visual areas? The spatial organi…
View article: Decoding sound content in the early visual cortex of aphantasic participants
Decoding sound content in the early visual cortex of aphantasic participants Open
Listening to natural auditory scenes leads to distinct neuronal activity patterns in the early visual cortex (EVC) of blindfolded sighted and congenitally blind participants.1,2 This pattern of sound decoding is organized by eccentricity, …
View article: Is V1 a Cognitive Map?
Is V1 a Cognitive Map? Open
A ‘Cognitive Map’ is an internal model of space upon which we can scaffold our judgments about the world. The question this GAC seeks to resolve is whether V1 acts as a ‘Cognitive Map’ in humans? In answering this question, our goal is to …
View article: Experience-dependent predictions of feedforward and contextual information in mouse visual cortex
Experience-dependent predictions of feedforward and contextual information in mouse visual cortex Open
Neurons in primary visual cortex are driven by feedforward visual inputs and top-down contextual inputs. The nature of this contextual information is difficult to study, as responses to feedforward and top-down inputs overlap in time and a…
View article: The coming decade of digital brain research: A vision for neuroscience at the intersection of technology and computing
The coming decade of digital brain research: A vision for neuroscience at the intersection of technology and computing Open
In recent years, brain research has indisputably entered a new epoch, driven by substantial methodological advances and digitally enabled data integration and modelling at multiple scales—from molecules to the whole brain. Major advances a…
View article: Retinotopic biases in contextual feedback signals to V1 for object and scene processing
Retinotopic biases in contextual feedback signals to V1 for object and scene processing Open
Identifying the objects embedded in natural scenes relies on recurrent processing between lower and higher visual areas. How is cortical feedback information related to objects and scenes organised in lower visual areas? The spatial organi…
View article: Mnemonic but not contextual feedback signals defy dedifferentiation in the aging early visual cortex
Mnemonic but not contextual feedback signals defy dedifferentiation in the aging early visual cortex Open
Perception is an intricate interplay between feedforward visual input and internally generated feedback signals that comprise concurrent contextual and time-distant mnemonic (episodic and semantic) information. Yet, an unresolved question …
View article: Entrainment of neural oscillations during language processing in Early-Stage schizophrenia
Entrainment of neural oscillations during language processing in Early-Stage schizophrenia Open
Our results show that CHR-P participants involve impairments in theta-band entrainment during speech tracking in left primary auditory cortex while higher-order speech processing areas were intact. Moreover, the severity of aberrant percep…
View article: The cortical microcircuitry of predictions and context – a multi-scale perspective
The cortical microcircuitry of predictions and context – a multi-scale perspective Open
Conscious cognition depends on the ability of the neocortex to generate internal models of the outside world. During wakefulness, the neocortex maintains and updates knowledge of the world and uses this knowledge through top-down projectio…
View article: Perceptual priors add sensory detail to contextual feedback processing in V1
Perceptual priors add sensory detail to contextual feedback processing in V1 Open
How do we develop models of the world? Contextualising ambiguous information with previous experience allows us to form an enriched perception. Contextual information and prior knowledge facilitate perceptual processing, improving our reco…
View article: Advancing the science of consciousness: from ethics to clinical care
Advancing the science of consciousness: from ethics to clinical care Open
Significant advances in the scientific investigation of the neurobiology of consciousness have been slow to be translated into clinical settings, limited by factors of conceptual (e.g., what is consciousness?), methodological (e.g., how to…
View article: The Spatial Precision of Contextual Feedback Signals in Human V1
The Spatial Precision of Contextual Feedback Signals in Human V1 Open
Neurons in the primary visual cortex (V1) receive sensory inputs that describe small, local regions of the visual scene and cortical feedback inputs from higher visual areas processing the global scene context. Investigating the spatial pr…
View article: The coming decade of digital brain research - A vision for neuroscience at the intersection of technology and computing
The coming decade of digital brain research - A vision for neuroscience at the intersection of technology and computing Open
Brain research has in recent years indisputably entered a new epoch, driven by substantial methodological advances and digitally enabled data integration and modeling at multiple scales – from molecules to the whole system. Major advances …
View article: Concurrent contextual and time-distant mnemonic information co-exist as feedback in the human visual cortex
Concurrent contextual and time-distant mnemonic information co-exist as feedback in the human visual cortex Open
Efficient processing of the visual environment necessitates the integration of incoming sensory evidence with concurrent contextual inputs and mnemonic content from our past experiences. To examine how this integration takes place in the b…
View article: Feedback brings scene information to the representation of occluded image regions in area V1 of monkeys and humans
Feedback brings scene information to the representation of occluded image regions in area V1 of monkeys and humans Open
Neuronal activity in the primary visual cortex (V1) is driven by feedforward input from within the neurons’ receptive fields (RFs) and modulated by contextual information in regions surrounding the RF. The effect of contextual information …