Lars Rombo
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View article: Temporal distribution of Plasmodium falciparum recrudescence following artemisinin-based combination therapy: an individual participant data meta-analysis
Temporal distribution of Plasmodium falciparum recrudescence following artemisinin-based combination therapy: an individual participant data meta-analysis Open
View article: Chloroquine-susceptible and -resistant<i>Plasmodium falciparum</i>strains survive high chloroquine concentrations by becoming dormant but are eliminated by prolonged exposure
Chloroquine-susceptible and -resistant<i>Plasmodium falciparum</i>strains survive high chloroquine concentrations by becoming dormant but are eliminated by prolonged exposure Open
Background Plasmodium falciparum strains that are resistant to standard-dose chloroquine can be treated by higher chloroquine concentrations maintained for a longer time in vivo. Objectives To determine the relative importance of chloroqui…
View article: High-Dose Chloroquine for Uncomplicated Plasmodium falciparum Malaria Is Well Tolerated and Causes Similar QT Interval Prolongation as Standard-Dose Chloroquine in Children
High-Dose Chloroquine for Uncomplicated Plasmodium falciparum Malaria Is Well Tolerated and Causes Similar QT Interval Prolongation as Standard-Dose Chloroquine in Children Open
Higher chloroquine doses can effectively treat up to 93 to 96% of malaria infections caused by Plasmodium falciparum carrying the resistance-conferring chloroquine resistance transporter ( pfcrt ) 76T allele. The tolerability of 50 (double…
View article: Artemether-Lumefantrine versus Dihydroartemisinin-Piperaquine for Treatment of Uncomplicated Plasmodium falciparum Malaria in Children Aged Less than 15 Years in Guinea-Bissau – An Open-Label Non-Inferiority Randomised Clinical Trial
Artemether-Lumefantrine versus Dihydroartemisinin-Piperaquine for Treatment of Uncomplicated Plasmodium falciparum Malaria in Children Aged Less than 15 Years in Guinea-Bissau – An Open-Label Non-Inferiority Randomised Clinical Trial Open
ClinicalTrials.gov NTC01704508.
View article: High-Dose Chloroquine for Treatment of Chloroquine-Resistant<i>Plasmodium falciparum</i>Malaria
High-Dose Chloroquine for Treatment of Chloroquine-Resistant<i>Plasmodium falciparum</i>Malaria Open
Chloroquine resistance is dose dependent and can be overcome by higher, still well-tolerated doses.
View article: The effect of dose on the antimalarial efficacy of artemether–lumefantrine: a systematic review and pooled analysis of individual patient data
The effect of dose on the antimalarial efficacy of artemether–lumefantrine: a systematic review and pooled analysis of individual patient data Open