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View article: Effects of Ageing, Oestrogen Level and Altered Dietary Loading on Rat Mandibular Cartilage—A Polarised Light Microscopy Study
Effects of Ageing, Oestrogen Level and Altered Dietary Loading on Rat Mandibular Cartilage—A Polarised Light Microscopy Study Open
Objective The mandibular condylar cartilage (MCC) of rats was examined with polarised light microscopy (PLM) to study the effects of ageing, oestrogen level, and altered dietary loading on the structure of the MCC. Materials and Methods 96…
View article: Diagnostic performance of attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy for detecting osteoarthritis and rheumatoid arthritis from blood serum
Diagnostic performance of attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy for detecting osteoarthritis and rheumatoid arthritis from blood serum Open
Osteoarthritis (OA) and rheumatoid arthritis (RA) are the two most common rheumatic diseases worldwide, causing pain and disability. Both conditions are highly heterogeneous, and their onset occurs insidiously with non-specific symptoms, s…
View article: Diagnostic performance of Attenuated Total Reflectance Fourier Transform Infrared (ATR-FTIR) spectroscopy for detecting osteoarthritis and rheumatoid arthritis from blood serum
Diagnostic performance of Attenuated Total Reflectance Fourier Transform Infrared (ATR-FTIR) spectroscopy for detecting osteoarthritis and rheumatoid arthritis from blood serum Open
Osteoarthritis (OA) and rheumatoid arthritis (RA) are the two most common rheumatic diseases worldwide, causing pain and disability. Both conditions are highly heterogeneous, and their onset occurs insidiously with non-specific symptoms, s…
View article: Inter- and Intra-Day Precision of a Low-Cost and Wearable Bioelectrical Impedance Analysis Device
Inter- and Intra-Day Precision of a Low-Cost and Wearable Bioelectrical Impedance Analysis Device Open
Bioimpedance analysis (BIA) is a non-invasive and safe method to measure body composition. Nowadays, due to technological progress, smaller and cheaper devices allow the implementation of BIA into wearable devices. In this pilot study, we …
View article: Fourier‐transform infrared study on effects of ageing, oestrogen level and altered dietary loading on rat mandibular condylar cartilage
Fourier‐transform infrared study on effects of ageing, oestrogen level and altered dietary loading on rat mandibular condylar cartilage Open
Objective Mandibular condylar cartilage (MCC) of the rat was examined with the Fourier‐transform infrared (FITR) spectroscopic imaging to study the effects of ageing, oestrogen level and altered dietary loading on the structure of MCC. Mat…
View article: Diagnostic performance of attenuated total reflection Fourier-transform infrared spectroscopy for detecting COVID-19 from routine nasopharyngeal swab samples
Diagnostic performance of attenuated total reflection Fourier-transform infrared spectroscopy for detecting COVID-19 from routine nasopharyngeal swab samples Open
Attenuated total reflection Fourier-transform infrared (ATR-FTIR) spectroscopy coupled with machine learning-based partial least squares discriminant analysis (PLS-DA) was applied to study if severe acute respiratory syndrome coronavirus 2…
View article: Preclassification of Broadband and Sparse Infrared Data by Multiplicative Signal Correction Approach
Preclassification of Broadband and Sparse Infrared Data by Multiplicative Signal Correction Approach Open
Preclassification of raw infrared spectra has often been neglected in scientific literature. Separating spectra of low spectral quality, due to low signal-to-noise ratio, presence of artifacts, and low analyte presence, is crucial for accu…
View article: Suitable Cathode NMP Replacement for Efficient Sustainable Printed Li-Ion Batteries
Suitable Cathode NMP Replacement for Efficient Sustainable Printed Li-Ion Batteries Open
N-methyl-2-pyrrolidone (NMP) is the most common solvent for manufacturing cathode electrodes in the battery industry; however, it is becoming restricted in several countries due to its negative environmental impact. Taking into account tha…
View article: MXene‐Polymer Hybrid for High‐Performance Gas Sensor Prepared by Microwave‐Assisted In‐Situ Intercalation
MXene‐Polymer Hybrid for High‐Performance Gas Sensor Prepared by Microwave‐Assisted In‐Situ Intercalation Open
2D transition‐metal carbides (Ti 3 C 2 T x MXene) intercalated with organic molecules have been widely used in batteries and supercapacitors, but are quite rarely reported for gas sensing. Since Ti 3 C 2 T x is sensitive to oxygen, most me…
View article: Infrared spectroscopy is suitable for objective assessment of articular cartilage health
Infrared spectroscopy is suitable for objective assessment of articular cartilage health Open
The results indicate that FTIR-ATR spectroscopy can differentiate between healthy and osteoarthritic femoral, tibial and patellar human tissue. If combined with a fiber optic probe, FTIR-ATR spectroscopy could provide additional objective …
View article: Preprocessing Strategies for Sparse Infrared Spectroscopy: A Case Study on Cartilage Diagnostics
Preprocessing Strategies for Sparse Infrared Spectroscopy: A Case Study on Cartilage Diagnostics Open
The aim of the study was to optimize preprocessing of sparse infrared spectral data. The sparse data were obtained by reducing broadband Fourier transform infrared attenuated total reflectance spectra of bovine and human cartilage, as well…
View article: Optimization of measurement mode and sample processing for FTIR microspectroscopy in skin cancer research
Optimization of measurement mode and sample processing for FTIR microspectroscopy in skin cancer research Open
The spectra of identical samples measured in two different modes and with or without paraffin show a significant difference. The paraffinized samples measured in transflection mode showed the best accuracy in discriminating two melanoma ce…
View article: Diagnostic performance of attenuated total reflection Fourier-transform infrared spectroscopy for detecting COVID-19 from routine nasopharyngeal swab samples
Diagnostic performance of attenuated total reflection Fourier-transform infrared spectroscopy for detecting COVID-19 from routine nasopharyngeal swab samples Open
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing global COVID-19 pandemic since 2019 has led to increasing amount of research to study how to do fast screening and diagnosis to efficiently detect COVID-19 positive cases…
View article: Vibrational spectroscopy and its future applications in microbiology
Vibrational spectroscopy and its future applications in microbiology Open
Vibrational spectroscopic techniques, namely Fourier transform infrared (FTIR) and Raman spectroscopy, are based on the study of molecular vibrations, and they are complementary techniques to each other. This review provides an overview of…
View article: Long-term changes in mandibular bone microchemical quality after radiation therapy and underlying systemic malignancy: A pilot study
Long-term changes in mandibular bone microchemical quality after radiation therapy and underlying systemic malignancy: A pilot study Open
Radiation therapy (RT) is a treatment option for head and neck cancer (HNC), but 2% of RT patients may experience damage to the jawbone, resulting in osteoradionecrosis (ORN). The ORN can manifest years after RT exposure. Changes in the lo…
View article: Discrimination of melanoma cell lines with Fourier Transform Infrared (FTIR) spectroscopy
Discrimination of melanoma cell lines with Fourier Transform Infrared (FTIR) spectroscopy Open
Among skin cancers, melanoma is the lethal form and the leading cause of death in humans. Melanoma begins in melanocytes and is curable at early stages. Thus, early detection and evaluation of its metastatic potential are crucial for effec…
View article: Infrared Fiber-Optic Spectroscopy Detects Bovine Articular Cartilage Degeneration
Infrared Fiber-Optic Spectroscopy Detects Bovine Articular Cartilage Degeneration Open
Objective Joint injuries may lead to degeneration of cartilage tissue and initiate development of posttraumatic osteoarthritis. Arthroscopic surgeries can be used to treat joint injuries, but arthroscopic evaluation of articular cartilage …
View article: Raman spectroscopy is sensitive to biochemical changes related to various cartilage injuries
Raman spectroscopy is sensitive to biochemical changes related to various cartilage injuries Open
Raman spectroscopy is promising in vivo tool in various biomedical applications; moreover, in recent years, its use for characterizing articular cartilage degeneration has been developing. It has also shown potential for scoring the severi…
View article: Mineralization of dental tissues and caries lesions detailed with Raman microspectroscopic imaging
Mineralization of dental tissues and caries lesions detailed with Raman microspectroscopic imaging Open
In this paper, we evaluated the detailed mineral composition maps of human teeth with caries lesions using Raman microspectroscopic imaging.
View article: Discrimination of melanoma cell lines with Fourier Transform Infrared (FTIR) spectroscopy
Discrimination of melanoma cell lines with Fourier Transform Infrared (FTIR) spectroscopy Open
Among skin cancers, melanoma is the lethal form and the leading cause of death in humans. Melanoma begins in melanocytes and is curable at early stages. Thus, early detection and evaluation of its metastatic potential are crucial for effec…
View article: The use of Fourier Transform Infrared (FTIR) spectroscopy in skin cancer research: a systematic review
The use of Fourier Transform Infrared (FTIR) spectroscopy in skin cancer research: a systematic review Open
Skin cancers are one of the most frequently occurring diseases in humans that pose severe health issues. Fourier Transform Infrared (FTIR) spectroscopy in cancer research has gained considerable attention because of its ability to provide …
View article: Infrared fiber optic spectroscopy detects bovine articular cartilage degeneration
Infrared fiber optic spectroscopy detects bovine articular cartilage degeneration Open
Articular cartilage (AC) is a soft connective tissue that covers the ends of articulating bones. Joint injuries may lead to degeneration of cartilage tissue and initiate development of post-traumatic osteoarthritis (OA). Arthroscopic surge…
View article: Raman microspectroscopic analysis of the tissue-specific composition of the human osteochondral junction in osteoarthritis: A pilot study
Raman microspectroscopic analysis of the tissue-specific composition of the human osteochondral junction in osteoarthritis: A pilot study Open
This study investigates the influence of osteoarthritis (OA) disease severity on the bio-composition of the osteochondral junction at the human tibial plateau using Raman microspectroscopy. We specifically aim to analyze the spatial compos…
View article: Histochemical quantification of collagen content in articular cartilage
Histochemical quantification of collagen content in articular cartilage Open
Based on our findings, modified Masson's trichrome staining protocol is suitable for quantification of AC collagen content. Enzymatic removal of PGs prior to staining is critical as us allows better staining of the collagen. Further optimi…