László Makrai
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View article: A One Health Approach Metagenomic Study on Antimicrobial Resistance Traits of Canine Saliva
A One Health Approach Metagenomic Study on Antimicrobial Resistance Traits of Canine Saliva Open
Background: According to the One Health concept, the physical proximity between pets and their owners facilitates the interspecies spread of bacteria including those that may harbor numerous antimicrobial resistance genes (ARGs). Methods: …
View article: Determination of Minimum Inhibitory Concentrations of Selected Antibiotics Against Trueperella pyogenes Originated from Bovine Clinical Endometritis
Determination of Minimum Inhibitory Concentrations of Selected Antibiotics Against Trueperella pyogenes Originated from Bovine Clinical Endometritis Open
Bacteriological examination of uterine secretions provides essential information for the prevalence of bovine uterine pathogens and their influence on fertility. The objective of the present study was to determine the uterine pathogens in …
View article: Mycoplasma hyopharyngis isolated from the joint of a weaner: A case report
Mycoplasma hyopharyngis isolated from the joint of a weaner: A case report Open
Background Mycoplasma hyopharyngis is a commensal bacterium in the upper respiratory tract of swine. As it is recognized to be apathogenic, examinations regarding this species are scarce, compared to other swine mycoplasmas. However, in a …
View article: Comprehensive Metagenomic Analysis of Veterinary Probiotics in Broiler Chickens
Comprehensive Metagenomic Analysis of Veterinary Probiotics in Broiler Chickens Open
Probiotics are widely used in broiler chickens to support the gut microbiome, gut health, and to reduce the amount of antibiotics used. Despite their benefits, there is concern over their ability to carry and spread antimicrobial resistanc…
View article: Molecular Markers and Antimicrobial Resistance Patterns of Extraintestinal Pathogenic Escherichia coli from Camel Calves Including Colistin-Resistant and Hypermucoviscuous Strains
Molecular Markers and Antimicrobial Resistance Patterns of Extraintestinal Pathogenic Escherichia coli from Camel Calves Including Colistin-Resistant and Hypermucoviscuous Strains Open
Extraintestinal pathogenic Escherichia coli (ExPEC) strains are capable of causing various systemic infections in both humans and animals. In this study, we isolated and characterized 30 E. coli strains from the parenchymatic organs and br…
View article: Apis mellifera filamentous virus from a honey bee gut microbiome survey in Hungary
Apis mellifera filamentous virus from a honey bee gut microbiome survey in Hungary Open
In Hungary, as part of a nationwide, climatically balanced survey for a next-generation sequencing-based study of the honey bee ( Apis mellifera ) gut microbiome, repeated sampling was carried out during the honey production season (March …
View article: Genomic epidemiology of antifungal resistance in human and avian isolates of Candida albicans: a pilot study from the One Health perspective
Genomic epidemiology of antifungal resistance in human and avian isolates of Candida albicans: a pilot study from the One Health perspective Open
Stress-induced genomic changes in Candida albicans contribute to the adaptation of this species to various environmental conditions. Variations of the genome composition of animal-origin C. albicans strains are largely unexplored and drug …
View article: Examination of the Virulence of Actinobacillus pleuropneumoniae Serovar 16 in Pigs
Examination of the Virulence of Actinobacillus pleuropneumoniae Serovar 16 in Pigs Open
Different virulence variants of A. pleuropneumoniae are involved in the etiology of porcine pleuropneumonia. The purpose of the present trial was examination of the virulence of the Actinobacillus pleuropneumoniae A-85/14 strain, the type …
View article: A One Health approach metagenomic study on the antimicrobial resistance traits of canine saliva
A One Health approach metagenomic study on the antimicrobial resistance traits of canine saliva Open
According to the One Health concept, physical proximity among pets and their owners facilitates the spread of various bacteria. Interspecies bacterial transfer media include canine saliva that can be transmitted by licking and biting. Anti…
View article: <i>Ixodes ricinus</i> tick bacteriome alterations based on a climatically representative survey in Hungary
<i>Ixodes ricinus</i> tick bacteriome alterations based on a climatically representative survey in Hungary Open
The microbial communities of disease vectors may represent a key feature in several biological functions and thus deserve special attention in light of climate change and the consequent need to develop novel control strategies. Nevertheles…
View article: Agrobacterium Is a Proposed Suitable System for Bioassays and Resistance Studies on Antimicrobial Peptides with Plant Protection Potential
Agrobacterium Is a Proposed Suitable System for Bioassays and Resistance Studies on Antimicrobial Peptides with Plant Protection Potential Open
Keywords: Agrobacterium 1; Xenorhabdus 2; NR-AMP 3 T-DNA keyword 4; TI-plasmid 5; Intact/Cured/T-DNA Deleted 6 Sensitive/Resistant 7; EMA_PF2 8; HPLC 9
View article: Bacterial colony size growth estimation by deep learning
Bacterial colony size growth estimation by deep learning Open
The bacterial growth rate is important for pathogenicity and food safety. Therefore, the study of bacterial growth rate over time can provide important data from a medical and veterinary point of view. We trained convolutional neural netwo…
View article: Antimicrobial Peptides (AMP) in the Cell-Free Culture Media of Xenorhabdus budapestensis and X. szentirmaii Exert Anti-Protist Activity against Eukaryotic Vertebrate Pathogens including Histomonas meleagridis and Leishmania donovani Species
Antimicrobial Peptides (AMP) in the Cell-Free Culture Media of Xenorhabdus budapestensis and X. szentirmaii Exert Anti-Protist Activity against Eukaryotic Vertebrate Pathogens including Histomonas meleagridis and Leishmania donovani Species Open
Anti-microbial peptides provide a powerful toolkit for combating multidrug resistance. Combating eukaryotic pathogens is complicated because the intracellular drug targets in the eukaryotic pathogen are frequently homologs of cellular stru…
View article: Susceptibility of Actinobacillus pleuropneumoniae, Pasteurella multocida and Streptococcus suis Isolated from Pigs in Hungary between 2018 and 2021
Susceptibility of Actinobacillus pleuropneumoniae, Pasteurella multocida and Streptococcus suis Isolated from Pigs in Hungary between 2018 and 2021 Open
Porcine respiratory disease complex (PRDC) has been a major animal health, welfare, and economic problem in Hungary; therefore, great emphasis should be put on both the prevention and control of this complex disease. As antibacterial agent…
View article: Antimicrobial Peptides for Combating Eukaryotic Pathogens: Anti-Histomonal, and Anti-Leishmanial Potential of Antimicrobial Peptides Released by Entomopathogenic Nematode Symbiont Bacteria
Antimicrobial Peptides for Combating Eukaryotic Pathogens: Anti-Histomonal, and Anti-Leishmanial Potential of Antimicrobial Peptides Released by Entomopathogenic Nematode Symbiont Bacteria Open
Antimicrobial peptides provide a powerful toolkit for combating multidrug resistance. Combatting eukaryotic pathogens is complicated by the fact, the intracellular drug targets in the eukaryotic pathogen are frequently homologs of cellular…
View article: Annotated dataset for deep-learning-based bacterial colony detection
Annotated dataset for deep-learning-based bacterial colony detection Open
View article: <i>Apis mellifera</i>filamentous virus from a honey bee gut microbiome survey in Hungary
<i>Apis mellifera</i>filamentous virus from a honey bee gut microbiome survey in Hungary Open
In Hungary, as part of a nationwide, climatically balanced survey for a next-generation sequencing-based study of the honey bee ( Apis mellifera ) gut microbiome, repeated sampling was carried out during the honey production season (March …
View article: Molecular epidemiology of Candida albicans infections revealed dominant genotypes in waterfowls diagnosed with esophageal mycosis
Molecular epidemiology of Candida albicans infections revealed dominant genotypes in waterfowls diagnosed with esophageal mycosis Open
Fungal infections of animals could yield significant economic losses, especially in the poultry industry, due to their adverse effects on growth, feed intake, digestion, and reproduction. Previous investigations showed that Candida albican…
View article: Antimicrobial resistance gene lack in tick-borne pathogenic bacteria
Antimicrobial resistance gene lack in tick-borne pathogenic bacteria Open
View article: Annotated dataset for deep-learning-based bacterial colony detection
Annotated dataset for deep-learning-based bacterial colony detection Open
Quantifying bacteria per unit mass or volume is a common task in various fields of microbiology (e.g., infectiology, and food hygiene). Most bacteria can be grown on culture media. The unicellular bacteria reproduce by dividing into two ce…
View article: Bacterial colony size growth estimation by deep learning
Bacterial colony size growth estimation by deep learning Open
The bacterial growth rate is important for pathogenicity and food safety. Therefore, the study of bacterial growth rate over time can provide important data from a medical and veterinary point of view. We trained convolutional neural netwo…
View article: XENOFOOD—An Autoclaved Feed Supplement Containing Autoclavable Antimicrobial Peptides—Exerts Anticoccidial GI Activity, and Causes Bursa Enlargement, but Has No Detectable Harmful Effects in Broiler Cockerels despite In Vitro Detectable Cytotoxicity on LHM Cells
XENOFOOD—An Autoclaved Feed Supplement Containing Autoclavable Antimicrobial Peptides—Exerts Anticoccidial GI Activity, and Causes Bursa Enlargement, but Has No Detectable Harmful Effects in Broiler Cockerels despite In Vitro Detectable Cytotoxicity on LHM Cells Open
Entomopathogenic bacteria are obligate symbionts of entomopathogenic nematode (EPN) species. These bacteria biosynthesize and release non-ribosomal-templated hybrid peptides (NR-AMPs), with strong, and large-spectral antimicrobial potentia…
View article: XENOFOOD - An Autoclaved Feed Supplement Containing Autoclavable Antimicrobial Peptides - Exerts Anticoccidial GI Activity, and Causes Bursa Enlargement, But Has No Detectable Harmful Effects In Broiler Cockerels Despite <em>In Vitro</em> Cytotoxic Ingredients
XENOFOOD - An Autoclaved Feed Supplement Containing Autoclavable Antimicrobial Peptides - Exerts Anticoccidial GI Activity, and Causes Bursa Enlargement, But Has No Detectable Harmful Effects In Broiler Cockerels Despite <em>In Vitro</em> Cytotoxic Ingredients Open
Whether the different NR-AMPs could ever be utilized as drugs not only against prokaryotic (bacteria) pathogens but eukaryotic (fungal pathogens, and parasitic protists) depends on the side effects. To get experimental experience about the…
View article: Porcine cytomegalovirus detection by nanopore-based metagenomic sequencing in a Hungarian pig farm
Porcine cytomegalovirus detection by nanopore-based metagenomic sequencing in a Hungarian pig farm Open
The rapid diagnosis of infectious diseases has an essential impact on their control, treatment and recovery. Oxford Nanopore Technologies (ONT) sequencing opens up a new dimension in applying clinical metagenomics. In a large-scale pig far…
View article: Antimicrobial resistance gene lack in tick-borne pathogenic bacteria
Antimicrobial resistance gene lack in tick-borne pathogenic bacteria Open
Tick-borne infections, including those of bacterial origin, are significant public health issues. Antimicrobial resistance (AMR), which is one of the most pressing health challenges of our time, is driven by specific genetic determinants, …
View article: Canine Saliva as a Possible Source of Antimicrobial Resistance Genes
Canine Saliva as a Possible Source of Antimicrobial Resistance Genes Open
While the One Health issues of intensive animal farming are commonly discussed, keeping companion animals is less associated with the interspecies headway of antimicrobial resistance. With the constant advance in veterinary standards, anti…
View article: <i>Ixodes ricinus</i>tick bacteriome alterations based on a climatically representative survey in Hungary
<i>Ixodes ricinus</i>tick bacteriome alterations based on a climatically representative survey in Hungary Open
Background The microbial communities of disease vectors may represent a key feature in several biological functions and thus deserve special attention in light of climate change and the consequent need to develop novel control strategies. …
View article: Genetic Diversity of Actinobacillus pleuropneumoniae Serovars in Hungary
Genetic Diversity of Actinobacillus pleuropneumoniae Serovars in Hungary Open
A total of 114 Actinobacillus pleuropneumoniae isolates from porcine hemorrhagic necrotic pleuropneumonia were characterized by the examination of biotype, serovar, antibiotic resistance genes, and genes of toxin production. Pulsed-field g…
View article: Natural diversity of the honey bee (Apis mellifera) gut bacteriome in various climatic and seasonal states
Natural diversity of the honey bee (Apis mellifera) gut bacteriome in various climatic and seasonal states Open
As pollinators and producers of numerous human-consumed products, honey bees have great ecological, economic and health importance. The composition of their bacteriota, for which the available knowledge is limited, is essential for their b…
View article: Molecular Phylogenetic Analysis of Candida krusei
Molecular Phylogenetic Analysis of Candida krusei Open