Latika Gupta
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View article: SARS-CoV-2 putative mi-RNAs may target host immune system and cellular mechanisms to mediate pathogenesis-an in silico and in vivo study
SARS-CoV-2 putative mi-RNAs may target host immune system and cellular mechanisms to mediate pathogenesis-an in silico and in vivo study Open
Introduction: The exact role of epigenetics in the pathogenesis of severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) is unclear. Herein we have hypothesized that viral micro RNAs (miRNAs) may modulate host cellular and immune r…
View article: Effectiveness of interventions to improve vaccine efficacy: a systematic review and meta-analysis
Effectiveness of interventions to improve vaccine efficacy: a systematic review and meta-analysis Open
PROSPERO CRD42024543608.
View article: The association between quality of life, intensity of counseling and health literacy amongst patients with nephrolithiasis
The association between quality of life, intensity of counseling and health literacy amongst patients with nephrolithiasis Open
Objectives The American Urological Association (AUA) provides guidance on primary prevention for nephrolithiasis; however, patient compliance is often poor. The role of healthy literacy in the primary prevention of nephrolithiasis is not w…
View article: SOCIAL MEDIA AND GERIATRIC HEALTH: PROMISES AND PITFALLS
SOCIAL MEDIA AND GERIATRIC HEALTH: PROMISES AND PITFALLS Open
SOCIAL MEDIA AND GERIATRIC HEALTH: PROMISES AND PITFALLS
View article: E082 Self-efficacy as a key contributor to improved health outcomes in patients with idiopathic inflammatory myopathies
E082 Self-efficacy as a key contributor to improved health outcomes in patients with idiopathic inflammatory myopathies Open
Background/Aims Self-efficacy is crucial in chronic disease management, affecting patients’ ability to cope with symptoms and adhere to treatments. Enhancing self-efficacy may reduce morbidity and mortality, lower healthcare costs, and imp…
View article: Racial, Ethnic, Sex, and Geographical Diversity in Myositis Clinical Trials
Racial, Ethnic, Sex, and Geographical Diversity in Myositis Clinical Trials Open
Objective The number of randomized clinical trials (RCTs) with patients with idiopathic inflammatory myopathies (IIMs) has grown exponentially over the last decade. Race, ethnicity, and sex reporting and representation of participants as w…
View article: Determinants of physical function, as measured using PROMIS PF-10a, in patients with rheumatoid arthritis: results from the international COVID-19 Vaccination in Autoimmune Diseases (COVAD) study
Determinants of physical function, as measured using PROMIS PF-10a, in patients with rheumatoid arthritis: results from the international COVID-19 Vaccination in Autoimmune Diseases (COVAD) study Open
Objectives Physical function in RA is largely influenced by multiple clinical factors, however, there is a growing body of evidence that psychological state and other comorbidities also play an essential role. Using data obtained in the CO…
View article: COVID-19 vaccination-related delayed adverse events among people with rheumatoid arthritis: results from the international COVAD survey
COVID-19 vaccination-related delayed adverse events among people with rheumatoid arthritis: results from the international COVAD survey Open
This study aimed to assess COVID-19 vaccination-related AEs in patients with rheumatoid arthritis (RA), in the COVID-19 Vaccination in Autoimmune Diseases (COVAD)-2 study. An online international cross-sectional survey captured self-report…
View article: Clinical Characteristics of Anti‐Synthetase Syndrome: Analysis From the Classification Criteria for Anti‐Synthetase Syndrome Project
Clinical Characteristics of Anti‐Synthetase Syndrome: Analysis From the Classification Criteria for Anti‐Synthetase Syndrome Project Open
Objective Anti‐synthetase syndrome (ASSD) is a rare systemic autoimmune rheumatic disease (SARD) with significant heterogeneity and no shared classification criteria. We aimed to identify clinical and serological features associated with A…
View article: Basic concepts in preserving holistic well-being in interstitial lung diseases: A MIHRA and G-FoRSS collaborative summary
Basic concepts in preserving holistic well-being in interstitial lung diseases: A MIHRA and G-FoRSS collaborative summary Open
Background: Interstitial lung diseases (ILD) are a heterogenous group of diseases that involve inflammation and/or fibrosis of the lung parenchyma. ILD can exert significant stress on a person’s extrapulmonary systems, eroding organ and ph…
View article: UNEQUAL AGING: DISPARITIES IN GERIATRIC RESEARCH AND A CALL FOR UNIFIED ACTION
UNEQUAL AGING: DISPARITIES IN GERIATRIC RESEARCH AND A CALL FOR UNIFIED ACTION Open
An increase in aging population poses significant challenges which are more pronounced in low- and lower middleincome countries. This editorial explores the multifaceted challenges in geriatric research such as demographic disparities, met…
View article: The impact of multimorbidity on Quality of Life in inflammatory myopathies: A cluster analysis from the COVAD dataset
The impact of multimorbidity on Quality of Life in inflammatory myopathies: A cluster analysis from the COVAD dataset Open
Objective The presence of comorbidities can substantially affect patients’ quality of life, but data regarding their impact on idiopathic inflammatory myopathies (IIMs) are limited. Methods We examined the prevalence of comorbidities in II…
View article: Management of bone health in idiopathic inflammatory myopathies: A two‐center audit in the <scp>United Kingdom</scp> and Hong Kong
Management of bone health in idiopathic inflammatory myopathies: A two‐center audit in the <span>United Kingdom</span> and Hong Kong Open
Background Patients with inflammatory idiopathic myopathies (IIM) face elevated risks of osteoporosis and fragility fracture. Aim To evaluate current practice relating to bone health in adult patients with IIM in the United Kingdom and Hon…
View article: Statin‐associated muscle symptoms: A comprehensive exploration of epidemiology, pathophysiology, diagnosis, and clinical management strategies
Statin‐associated muscle symptoms: A comprehensive exploration of epidemiology, pathophysiology, diagnosis, and clinical management strategies Open
Statins are the first line of treatment for both primary and secondary prevention of atherosclerotic cardiovascular disease. Despite the positive effects of statins on cardiovascular events, not all patients can use them at an optimized do…
View article: COVID-19 severity, breakthrough infections and vaccine safety in young individuals with autoimmune diseases: insights from the COVAD study
COVID-19 severity, breakthrough infections and vaccine safety in young individuals with autoimmune diseases: insights from the COVAD study Open
Notwithstanding the wealth of literature on COVID-19, studies focusing on young adults with autoimmune diseases (AD) are lacking. To determine early (within 7 days) and late (after 7 days) anti-SARS-CoV-2 vaccine-related adverse events (AE…
View article: The curious case of subcutaneous dirofilariasis mimicking a fibroma – Report of a rare disease from North India
The curious case of subcutaneous dirofilariasis mimicking a fibroma – Report of a rare disease from North India Open
Human dirofilariasis is a rare arthropod-borne zoonotic infection caused by a filarial nematode of the genus Dirofilaria . It typically manifests in humans as pulmonary, ocular, or subcutaneous lesions. In India, the disease is predominant…
View article: Prompt engineering: The next big skill in rheumatology research
Prompt engineering: The next big skill in rheumatology research Open
Large language models (LLMs) like GPT‐4 and Claude are catalyzing transformation across medical research including rheumatology. This review examines their applications, highlighting the pivotal role of prompt engineering in effectively gu…
View article: Listening to patients, for the patients: The <scp>COVAD</scp> Study—Vision, organizational structure, and challenges
Listening to patients, for the patients: The <span>COVAD</span> Study—Vision, organizational structure, and challenges Open
Background The pandemic presented unique challenges for individuals with autoimmune and rheumatic diseases (AIRDs) due to their underlying condition, the effects of immunosuppressive treatments, and increased vaccine hesitancy. Objectives …
View article: Characteristics of emerging new autoimmune diseases after <scp>COVID</scp>‐19 vaccination: A sub‐study by the <scp>COVAD</scp> group
Characteristics of emerging new autoimmune diseases after <span>COVID</span>‐19 vaccination: A sub‐study by the <span>COVAD</span> group Open
Background Despite the overall safety and efficacy of COVID‐19 vaccinations, rare cases of systemic autoimmune diseases (SAIDs) have been reported post‐vaccination. This study used a global survey to analyze SAIDs in susceptible individual…
View article: Prolonged viral shedding following COVID-19 infection in a rheumatoid patient on rituximab treatment
Prolonged viral shedding following COVID-19 infection in a rheumatoid patient on rituximab treatment Open
Sir, Since the beginning of the COVID-19 pandemic, we have seen several ways the disease can present, while it mostly manifests as a mild self-limiting upper respiratory infection in immune-competent individuals though a severe and variabl…