Laura Steenberge
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View article: P-2120. Clinical significance of 16S rRNA sequencing identification of <i>Legionella</i> species
P-2120. Clinical significance of 16S rRNA sequencing identification of <i>Legionella</i> species Open
Background Incorporation of 16S rRNA sequencing into clinical diagnostics has improved the ability of clinicians to diagnose fastidious bacteria and facilitates the identification of causative organisms in culture-negative infections. Howe…
View article: <i>Staphylococcus aureus</i> lipid factors modulate melanoma cell clustering and invasion
<i>Staphylococcus aureus</i> lipid factors modulate melanoma cell clustering and invasion Open
The microbiome can influence cancer development and progression. However, less is known about the role of the skin microbiota in melanoma. Here, we took advantage of a zebrafish melanoma model to probe the effects of Staphylococcus aureus …
View article: Systematic analysis of NDUFAF6 in complex I assembly and mitochondrial disease
Systematic analysis of NDUFAF6 in complex I assembly and mitochondrial disease Open
View article: Yes, It Is Polyphony and a Map: Revisiting the 72 Verses of St. Martial
Yes, It Is Polyphony and a Map: Revisiting the 72 Verses of St. Martial Open
The enigmatic 72 Verses for St. Martial is one of the many works by Ademar de Chabannes (989–1034) crafted to promote the false narrative that St. Martial of Limoges, rather than being a third-century bishop, was actually a first-century a…
View article: Coenzyme Q4 is a functional substitute for coenzyme Q10 and can be targeted to the mitochondria
Coenzyme Q4 is a functional substitute for coenzyme Q10 and can be targeted to the mitochondria Open
Coenzyme Q10 (CoQ10) is an important cofactor and antioxidant for numerous cellular processes, and its deficiency has been linked to human disorders including mitochondrial disease, heart failure, Parkinson's disease, and hypert…
View article: Staphylococcus aureus lipid factors modulate melanoma clustering and invasion in zebrafish
Staphylococcus aureus lipid factors modulate melanoma clustering and invasion in zebrafish Open
The microbiome can influence cancer development and progression. However, less is known about the role of the skin microbiota in melanoma. Here, we take advantage of a zebrafish melanoma model to probe the effects of Staphylococcus aureus …
View article: Systematic analysis of NDUFAF6 in complex I assembly and mitochondrial disease
Systematic analysis of NDUFAF6 in complex I assembly and mitochondrial disease Open
Isolated complex I (CI) deficiencies are a major cause of primary mitochondrial disease. Two-thirds of CI deficiencies arise from defects in CI assembly factors (CIAFs) that are not part of the CI holoenzyme. The biochemistry of CIAFs is p…
View article: Coenzyme Q<sub>4</sub>is a functional substitute for coenzyme Q<sub>10</sub>and can be targeted to the mitochondria
Coenzyme Q<sub>4</sub>is a functional substitute for coenzyme Q<sub>10</sub>and can be targeted to the mitochondria Open
Coenzyme Q 10 (CoQ 10 ) is an important cofactor and antioxidant for numerous cellular processes, and its deficiency has been linked to human disorders including mitochondrial disease, heart failure, Parkinson’s disease, and hypertension. …
View article: The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity
The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity Open
Stress resistance and longevity are positively correlated but emerging evidence indicates that they are physiologically distinct. Identifying factors with distinctive roles in these processes is challenging because pro-longevity genes ofte…
View article: Synthesis and Screen of a Proline-Rich Combinatorial Library Towards the Identification of Sickle Cell Hemoglobin Polymerization Inhibitors
Synthesis and Screen of a Proline-Rich Combinatorial Library Towards the Identification of Sickle Cell Hemoglobin Polymerization Inhibitors Open
Sickle cell disease is a genetic disorder that affects the hemoglobin within red blood cells. A point mutation in the gene coding for the β-subunit of hemoglobin allows the mutant chain to interact with a hydrophobic pocket of another hemo…