Laura Tregidgo
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View article: Update in Noninvasive Home Mechanical Ventilation: A Narrative Review of Indications, Outcomes, and Monitoring
Update in Noninvasive Home Mechanical Ventilation: A Narrative Review of Indications, Outcomes, and Monitoring Open
Hypercapnic respiratory failure arises due to an imbalance in the load‐capacity‐drive relationship of the respiratory muscle pump, typically arising in patients with chronic obstructive pulmonary disease, obesity‐related respiratory failur…
View article: Supporting patients with hypercapnia
Supporting patients with hypercapnia Open
Hypercapnia is commonly encountered by general and specialist respiratory clinicians. Patients at risk of developing hypercapnic respiratory failure include those with chronic obstructive pulmonary disease (COPD), obesity and neuromuscular…
View article: Delayed-onset disseminated BCG disease causing a multi-system illness with fatal mycotic aortic aneurysm
Delayed-onset disseminated BCG disease causing a multi-system illness with fatal mycotic aortic aneurysm Open
Case: We report a case of disseminated BCG infection, diagnosed two years after BCG infusion for bladder cancer. Our patient, a 74-year-old male, was referred with an 18-month history of fevers, weight loss and intermittent confusion. Prio…
View article: EP.TU.411Thinking Ahead: Improving Documentation of Treatment Escalation Plans for Surgical Patients
EP.TU.411Thinking Ahead: Improving Documentation of Treatment Escalation Plans for Surgical Patients Open
Aims The GMC recommends early decision making on CPR status for all acutely unwell patients admitted to hospital. An audit was undertaken of documentation of treatment escalation plans (TEPs) for general surgical patients at a District Gen…
View article: Antimicrobial Peptides SLPI and Beta Defensin-1 in Sputum are Negatively Correlated with FEV1
Antimicrobial Peptides SLPI and Beta Defensin-1 in Sputum are Negatively Correlated with FEV1 Open
Sputum SLPI and beta defensin-1 may be markers to identify those patients with declining lung function. ICS use was associated with higher sputum osteopontin compared to those with no ICS use.
View article: The Effect Of Corticosteroids On Internalisation Of Non-Typeable Haemophilus Influenzae Into Epithelial Cells
The Effect Of Corticosteroids On Internalisation Of Non-Typeable Haemophilus Influenzae Into Epithelial Cells Open