Laura Willinger
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View article: Molecular Mechanisms of Vascular Tone in Exercising Pediatric Populations: A Comprehensive Overview on Endothelial, Antioxidative, Metabolic and Lipoprotein Signaling Molecules
Molecular Mechanisms of Vascular Tone in Exercising Pediatric Populations: A Comprehensive Overview on Endothelial, Antioxidative, Metabolic and Lipoprotein Signaling Molecules Open
Vasoactive molecules are central regulators of vascular tone, angiogenesis and inflammation. Key molecular agents include nitric oxide (NO), endothelin-1 (ET-1), prostacyclin, free triiodothyronine (fT3), leptin, low-density lipoprotein (L…
View article: Interactive Telehealth Solutions for Patients With Congenital Heart Disease: A Systematic Review
Interactive Telehealth Solutions for Patients With Congenital Heart Disease: A Systematic Review Open
The majority of studies indicate that telehealth solutions have a positive impact on cardiovascular health. To ensure medical care for these patients, the implementation of more high-quality, interactive, and live telehealth solutions beyo…
View article: The MuCAYAplus Study—Influence of Physical Activity and Metabolic Parameters on the Structure and Function of the Cardiovascular System in Young Athletes
The MuCAYAplus Study—Influence of Physical Activity and Metabolic Parameters on the Structure and Function of the Cardiovascular System in Young Athletes Open
Exercise has a significant impact on the cardiovascular (CV) health of children and adolescents, with resultant alterations in CV structure and function being evident, even at an early age. Engagement in regular, moderate physical activity…
View article: Cardiopulmonary Exercise Test and Daily Physical Activity in Pediatric Congenital Heart Disease: an Exploratory Analysis
Cardiopulmonary Exercise Test and Daily Physical Activity in Pediatric Congenital Heart Disease: an Exploratory Analysis Open
Sedentary lifestyle is reported to be associated with diminished exercise capacity, resulting in increased cardiovascular risk in adults with congenital heart disease (CHD). This cross-sectional study examined the association between objec…
View article: KIJANI: Designing a Physical Activity Promoting Collaborative Augmented Reality Game
KIJANI: Designing a Physical Activity Promoting Collaborative Augmented Reality Game Open
Background: There is an increased need for physical activity among children and adolescents. KIJANI, a mobile augmented reality game, is designed to increase physical activity through gamified exercises. Objectives: The primary aim of this…
View article: KIJANI App to Promote Physical Activity in Children and Adolescents: Protocol for a Mixed Method Evaluation
KIJANI App to Promote Physical Activity in Children and Adolescents: Protocol for a Mixed Method Evaluation Open
Background The prevalence of physical inactivity among children and adolescents is alarmingly high despite the well-documented and comprehensive benefits of regular physical activity (PA). Therefore, PA promotion should start early in chil…
View article: Perceived Parental Style Is Better in Adults with Congenital Heart Disease than Healthy Controls—But There Is Work Left to Do in Specific Subgroups
Perceived Parental Style Is Better in Adults with Congenital Heart Disease than Healthy Controls—But There Is Work Left to Do in Specific Subgroups Open
Objective: To compare perceived parental style in a large cohort of adults with congenital heart disease (ACHD) to healthy reference (RCs). Furthermore, factors associated with perceived parental style were determined in ACHD. Patients and…
View article: Evaluation of the gamified application KIJANI to promote physical activity in children and adolescents: A multimethod study
Evaluation of the gamified application KIJANI to promote physical activity in children and adolescents: A multimethod study Open
Objective Digital approaches have the potential to make activity promotion attractive and age-appropriate for children and adolescents. KIJANI is a mobile application aiming to increase physical activity (PA) in youth via gamification and …
View article: KIJANI App to Promote Physical Activity in Children and Adolescents: Protocol for a Mixed Method Evaluation (Preprint)
KIJANI App to Promote Physical Activity in Children and Adolescents: Protocol for a Mixed Method Evaluation (Preprint) Open
BACKGROUND The prevalence of physical inactivity among children and adolescents is alarmingly high despite the well-documented and comprehensive benefits of regular physical activity (PA). Therefore, PA promotion should start early in chi…
View article: High-sensitive troponin T and N-terminal pro-B-type natriuretic peptide independently predict survival and cardiac-related events in adults with congenital heart disease
High-sensitive troponin T and N-terminal pro-B-type natriuretic peptide independently predict survival and cardiac-related events in adults with congenital heart disease Open
Aims High-sensitive troponin T (hs-TnT), N-terminal pro-B-type natriuretic peptide (NT-proBNP), and C-reactive protein (CRP) are established prognostic biomarkers for cardiovascular (CV) morbidity and mortality and frequently used in sympt…
View article: Abnormalities in pulmonary function and volumes in patients with CHD: a systematic review – ERRATUM
Abnormalities in pulmonary function and volumes in patients with CHD: a systematic review – ERRATUM Open
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View article: Diminished Endothelial Function but Normal Vascular Structure in Adults with Tetralogy of Fallot
Diminished Endothelial Function but Normal Vascular Structure in Adults with Tetralogy of Fallot Open
The life expectancy of patients with Tetralogy of Fallot (ToF) has increased in recent years. As a result, other risk factors with later onset in life are in the focus of patient care. Endothelial function is an early indicator of cardiova…
View article: Overweight and Obesity in Patients with Congenital Heart Disease: A Systematic Review
Overweight and Obesity in Patients with Congenital Heart Disease: A Systematic Review Open
Background: Overweight and obesity have become a major public health concern in recent decades, particularly in patients with chronic health conditions like congenital heart disease (CHD). This systematic review elaborates on the prevalenc…
View article: Association between Objectively Measured Physical Activity and Arterial Stiffness in Children with Congenital Heart Disease
Association between Objectively Measured Physical Activity and Arterial Stiffness in Children with Congenital Heart Disease Open
Background: The association between physical activity (PA) and arterial stiffness is particularly important in children with congenital heart disease (CHD) who are at risk for arterial stiffening. The aim of this study was to examine the a…