Laurane Mangé
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View article: A clinically relevant morpho-molecular classification of lung neuroendocrine tumours
A clinically relevant morpho-molecular classification of lung neuroendocrine tumours Open
Lung neuroendocrine tumours (NETs, also known as carcinoids) are rapidly rising in incidence worldwide but have unknown aetiology and limited therapeutic options beyond surgery. We conducted multi-omic analyses on over 300 lung NETs includ…
View article: Variability of mutational signatures is a footprint of carcinogens
Variability of mutational signatures is a footprint of carcinogens Open
Understanding the genomic impact of carcinogens is fundamental to cancer biology and prevention. However, recent coordinated efforts to detect such fingerprints have been largely unsuccessful, challenging the paradigm that carcinogens indu…