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View article: Non-autonomous Vnd acts with autonomous Appl during mushroom body axon growth in <i>Drosophila</i>
Non-autonomous Vnd acts with autonomous Appl during mushroom body axon growth in <i>Drosophila</i> Open
The Amyloid Precursor Protein (APP) is associated with Alzheimer’s disease. Appl is the single Drosophila APP ortholog and is expressed in all neurons throughout development. Appl was previously shown to cell-autonomously modulate axon out…
View article: Long-term memory formation depends on an astrocyte-to-neuron H<sub>2</sub>O<sub>2</sub>signaling
Long-term memory formation depends on an astrocyte-to-neuron H<sub>2</sub>O<sub>2</sub>signaling Open
Astrocytes interact with neurons during cognitive processes 1 . In particular, astrocytes help neurons to fight oxidative stress 2 , a needed function since active neurons are prone to reactive oxygen species (ROS) damage due to their high…
View article: Glial glucose fuels the neuronal pentose phosphate pathway for long-term memory
Glial glucose fuels the neuronal pentose phosphate pathway for long-term memory Open
Brain function relies almost solely on glucose as an energy substrate. The main model of brain metabolism proposes that glucose is taken up and converted into lactate by astrocytes to fuel the energy-demanding neuronal activity underlying …