Lauren J. N. Brent
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View article: Variation in trabecular bone microarchitecture across rhesus macaque ( <i>Macaca mulatta</i> ) load‐bearing joints
Variation in trabecular bone microarchitecture across rhesus macaque ( <i>Macaca mulatta</i> ) load‐bearing joints Open
Globally, human population structure is quickly trending older, increasing the prevalence and systemic burden of age‐related skeletal disorders such as osteoporosis. Osteoporosis is characterized by the loss of bone mass, including trabecu…
View article: The influence of captivity on cardiac structure and function across age, in rhesus macaques
The influence of captivity on cardiac structure and function across age, in rhesus macaques Open
Background Captive non-human primates are widely used as models of human aging, yet the conditions they live in differ markedly from their naturalistic environment. Differences between captive and free-ranging environments may impact how t…
View article: Quality, quantity, and the adaptive function of social relationships
Quality, quantity, and the adaptive function of social relationships Open
Affiliative social relationships have clear links to fitness in many species, yet exactly why that is the case remains elusive. We unify theory from socioecology and network science to set forth testable predictions of how individuals shou…
View article: Latent layers in social networks and their implications for comparative analyses
Latent layers in social networks and their implications for comparative analyses Open
Animal social systems are remarkably diverse, ranging from solitary individuals to well-connected cooperative groups. Understanding the drivers of this variation is a key question in behavioral ecology and has been the focus of numerous st…
View article: Observation methods in animal behaviour: a simulation study of performance
Observation methods in animal behaviour: a simulation study of performance Open
Most behavioural studies rely on systematic samples of behaviour, as observing and recording all behavioural events that occur is rarely feasible. Choosing an observation method involves several key decisions, including which individuals t…
View article: The ocular surface microbiome of rhesus macaques
The ocular surface microbiome of rhesus macaques Open
View article: Five misunderstandings in animal social network analysis
Five misunderstandings in animal social network analysis Open
Animal social network analysis has become central to behavioural ecology, offering powerful tools to explore the links between social behaviour and ecological or evolutionary processes. While rooted in the broader field of social network a…
View article: Age and early life adversity shape heterogeneity of the epigenome across tissues in macaques
Age and early life adversity shape heterogeneity of the epigenome across tissues in macaques Open
Age and early life adversity (ELA) are both key determinants of health, but whether they target similar physiological mechanisms across the body is unknown due to limited multi-tissue datasets from well-characterized cohorts. We generated …
View article: okaapi: an R package for generating social networks based on trait preferences
okaapi: an R package for generating social networks based on trait preferences Open
Modelling of simulated networks with generative network models plays a central role for our understanding of the emergence and consequences of network structures. Accessible software that generates simulated networks based on relevant proc…
View article: Quality, quantity, and the adaptive function of social relationships
Quality, quantity, and the adaptive function of social relationships Open
Affiliative social relationships have clear links to fitness in a variety of species, yet exactly why that is the case remains elusive. One major development has been the recognition that animals form different kinds of social relationship…
View article: Support for the social buffering hypothesis, especially under unpredictable precipitation regimes
Support for the social buffering hypothesis, especially under unpredictable precipitation regimes Open
Sociality is hypothesised to buffer populations against environmental stochasticity by stabilising key vital rates, yet this has rarely been tested across diverse taxa. We compiled demographic time series from 87 populations for 66 animal …
View article: The ocular surface microbiome of rhesus macaques
The ocular surface microbiome of rhesus macaques Open
View article: Socioecological drivers of injuries and aggression in female and male rhesus macaques (Macaca mulatta)
Socioecological drivers of injuries and aggression in female and male rhesus macaques (Macaca mulatta) Open
View article: MacaqueNet: Advancing comparative behavioural research through large‐scale collaboration
MacaqueNet: Advancing comparative behavioural research through large‐scale collaboration Open
There is a vast and ever‐accumulating amount of behavioural data on individually recognised animals, an incredible resource to shed light on the ecological and evolutionary drivers of variation in animal behaviour. Yet, the full potential …
View article: SIV infection induces alterations in gene expression and loss of interneurons in Rhesus Macaque frontal cortex during early systemic infection
SIV infection induces alterations in gene expression and loss of interneurons in Rhesus Macaque frontal cortex during early systemic infection Open
Understanding the neurobiological mechanisms underlying HIV-associated neurocognitive decline in people living with HIV is frequently complicated by an inability to analyze changes across the course of the infection and frequent presence o…
View article: Estimating realized relatedness in free-ranging macaques by inferring identity-by-descent segments
Estimating realized relatedness in free-ranging macaques by inferring identity-by-descent segments Open
Biological relatedness is a key consideration in studies of behavior, population structure, and trait evolution. Except for parent–offspring dyads, pedigrees capture relatedness imperfectly. The number and length of identical-by-descent DN…
View article: Data for Siracusa et al. 2023 Phil Trans - "Ageing in a collective: The impact of ageing individuals on social network structure"
Data for Siracusa et al. 2023 Phil Trans - "Ageing in a collective: The impact of ageing individuals on social network structure" Open
Data to recreate analyses found in Siracusa et al. 2023 Phil. Trans - "Ageing in a collective: The impact of ageing individuals on social network structure".Data updated on 29-Aug-25 due to previous error in how individual IDs were scrambl…
View article: Genetic Architecture of Immune Cell <scp>DNA</scp> Methylation in the Rhesus Macaque
Genetic Architecture of Immune Cell <span>DNA</span> Methylation in the Rhesus Macaque Open
Genetic variation that impacts gene regulation, rather than protein function, can have strong effects on trait variation both within and between species. Epigenetic mechanisms, such as DNA methylation, are often an important intermediate l…
View article: Social bonds between non-kin are common, but less stable, in a mixed-related society
Social bonds between non-kin are common, but less stable, in a mixed-related society Open
Members of social groups often form social relationships, which are known to carry important fitness benefits. Kin selection predicts that these relationships should be prevalent between kin, yet there is increasing evidence that, in socie…
View article: Analysis of sparse animal social networks
Analysis of sparse animal social networks Open
Low-density social networks can be common in animal societies, even among species generally considered to be highly social. Social network analysis is commonly used to analyse animal societal structure, but edge weight (strength of associa…
View article: Understanding age and society using natural populations
Understanding age and society using natural populations Open
Ageing affects almost all aspects of life and therefore is an important process across societies, human and non-human animal alike. This article introduces new research exploring the complex interplay between individual-level ageing and de…
View article: Social ageing can protect against infectious disease in a group-living primate
Social ageing can protect against infectious disease in a group-living primate Open
The benefits of social living are well established, but sociality also comes with costs, including infectious disease risk. This cost–benefit ratio of sociality is expected to change across individuals’ lifespans, which may drive changes i…
View article: Relationship between dominance hierarchy steepness and rank-relatedness of benefits in primates
Relationship between dominance hierarchy steepness and rank-relatedness of benefits in primates Open
In animal social groups, the extent to which individuals consistently win agonistic interactions and their ability to monopolize resources represent 2 core aspects of their competitive regime. However, whether these two aspects are closely…
View article: Immune gene regulation is associated with age and environmental adversity in a nonhuman primate
Immune gene regulation is associated with age and environmental adversity in a nonhuman primate Open
Phenotypic aging is ubiquitous across mammalian species, suggesting shared underlying mechanisms of aging. Aging is linked to molecular changes to DNA methylation and gene expression, and environmental factors, such as severe external chal…
View article: Evolutionary and biomedical implications of sex differences in the primate brain transcriptome
Evolutionary and biomedical implications of sex differences in the primate brain transcriptome Open
View article: Issue Information – Table of Contents
Issue Information – Table of Contents Open
View article: Trade-offs between sociality and gastrointestinal parasite infection in the context of a natural disaster
Trade-offs between sociality and gastrointestinal parasite infection in the context of a natural disaster Open
Parasites and infectious diseases constitute important challenges particularly for group-living animals. Social contact and shared space can both increase parasite transmission risk, while individual differences in social capital can help …
View article: Social ageing can protect against infectious disease in a group-living primate
Social ageing can protect against infectious disease in a group-living primate Open
The benefits of social living are well established, but sociality also comes with costs, including infectious disease risk. This cost-benefit ratio of sociality is expected to change across individuals’ lifespans, which may drive changes i…
View article: Mechanical and morphometric approaches to body mass estimation in rhesus macaques: A test of skeletal variables
Mechanical and morphometric approaches to body mass estimation in rhesus macaques: A test of skeletal variables Open
Objectives Estimation of body mass from skeletal metrics can reveal important insights into the paleobiology of archeological or fossil remains. The standard approach constructs predictive equations from postcrania, but studies have questi…
View article: Layers of latency in social networks and their implications for comparative analyses
Layers of latency in social networks and their implications for comparative analyses Open
Animal social systems are remarkably diverse. Linking this diversity to its ecological and evolutionary drivers and consequences has been a major focus of biological research. Initial efforts have been done within groups, populations, and …