Lauren Wisnieski
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View article: Pet companionship and binge drinking in the context of identity-related adversity: A study of LGBTQ+ emerging adults
Pet companionship and binge drinking in the context of identity-related adversity: A study of LGBTQ+ emerging adults Open
Background : Emerging adulthood (ages 18–25) is marked by developmental transitions, increased autonomy, and identity exploration. It is also a period of elevated risk for health-compromising behaviors, including binge drinking. LGBTQ+ eme…
View article: Detection of leptospiral antibodies and DNA in freshwater fish
Detection of leptospiral antibodies and DNA in freshwater fish Open
Leptospirosis is an important zoonotic disease that is maintained in populations due to chronic kidney infection of reservoir mammals. Previous work from our lab has identified rodents, voles, shrews, chipmunks and several species of amphi…
View article: Identity-related stressors and human-animal bonds: Associations with nicotine and cannabis use among LGBTQ+ emerging adults
Identity-related stressors and human-animal bonds: Associations with nicotine and cannabis use among LGBTQ+ emerging adults Open
LGBTQ+ emerging adults frequently face stressors that heighten their risk of maladaptive coping behaviors, including substance use (SU). This study explores relationships between stressors associated with gender identity and expression (di…
View article: Factors influencing equine veterinarians' job satisfaction and retention: A focus group study
Factors influencing equine veterinarians' job satisfaction and retention: A focus group study Open
Background There is a shortage of equine veterinarians. Understanding what factors are associated with job satisfaction in equine veterinarians can inform interventions to increase retention in equine medicine. Objective To explore the pro…
View article: One Health research at Lincoln Memorial University
One Health research at Lincoln Memorial University Open
View article: The intersection of Interprofessional Education and One Health: A qualitative study in human and veterinary medical institutions
The intersection of Interprofessional Education and One Health: A qualitative study in human and veterinary medical institutions Open
Interprofessional Education (IPE) and One Health are two common and overlapping frameworks for teaching collaborative practice. IPE is common at human medical institutions, while One Health is more common in graduate and veterinary program…
View article: Wave-Based Outcomes Comparison of Hospitalized COVID-19 Patients: A Retrospective Multicenter Cohort Study From Rural Appalachia
Wave-Based Outcomes Comparison of Hospitalized COVID-19 Patients: A Retrospective Multicenter Cohort Study From Rural Appalachia Open
This study comprehensively characterizes the impact of the COVID-19 pandemic in rural regions of Appalachian Kentucky and West Virginia. Future studies comparing differences between rural and urban geographies may be able to distinguish wh…
View article: Factors Associated with Behavioral Health Outcomes in Veterinarians Involved in Disaster Responses
Factors Associated with Behavioral Health Outcomes in Veterinarians Involved in Disaster Responses Open
Objective The objective of this study was to determine what factors are associated with behavioral health in veterinary disaster responders. Methods An online cross-sectional survey was distributed via snowball sampling. Results were analy…
View article: The Intersection of Interprofessional Education and One Health: A Qualitative Study in Human and Veterinary Medical Institutions
The Intersection of Interprofessional Education and One Health: A Qualitative Study in Human and Veterinary Medical Institutions Open
View article: Challenges and Opportunities in One Health: Google Trends Search Data
Challenges and Opportunities in One Health: Google Trends Search Data Open
Google Trends data can be informative for zoonotic disease incidences, including Lyme disease. However, the use of Google Trends for predictive purposes is underutilized. In this study, we demonstrate the potential to use Google Trends for…
View article: Challenges and Opportunities in One Health: Google Trends Search Data
Challenges and Opportunities in One Health: Google Trends Search Data Open
Google Trends data can be informative for infectious disease incidences, including Lyme disease. However, the use of Google Trends for predictive purposes is underutilized. In this study, we tested the ability of Google Trends search data …
View article: Prevalence and Factors of Self-medication with Antibiotics in Claiborne County, Tennessee
Prevalence and Factors of Self-medication with Antibiotics in Claiborne County, Tennessee Open
Introduction: Antimicrobial resistance (AMR) is a serious concern to public health, causing an estimated 35,000 deaths annually in the U.S. Misuse of antimicrobials increases the rate of AMR. Self-medication with antibiotics (SMA) is a pri…
View article: Canine Heartworm Infection and Prophylaxis Use among Pet Caretakers from the Cumberland Gap Region of Tennessee, USA
Canine Heartworm Infection and Prophylaxis Use among Pet Caretakers from the Cumberland Gap Region of Tennessee, USA Open
The prevalence of infection with canine heartworm (CHW), Dirofilaria immitis, continues to increase across the United States, regardless of the availability of effective and affordable prophylactic products. Current reports of CHW prevalen…
View article: Factors associated with heartworm preventative use in the golden retriever lifetime study
Factors associated with heartworm preventative use in the golden retriever lifetime study Open
Introduction Heartworm disease is preventable with use of heartworm preventatives, but the reported prevalence of heartworm preventative use in the United States is low, some estimates falling around 50% of dogs. However, there are very fe…
View article: The association of pet ownership and sleep quality and sleep disorders in United States adults
The association of pet ownership and sleep quality and sleep disorders in United States adults Open
Prior studies on the association between pet ownership and sleep quality and sleep disorders have varied results. Pet ownership may be beneficial for an owner’s quality of sleep due to the social support that pets provide. Pets offer a sen…
View article: Outcomes of Heart Failure in COVID-19 Patients: An Appalachian Experience
Outcomes of Heart Failure in COVID-19 Patients: An Appalachian Experience Open
Our study confirms previous findings of poor outcome in HF patients with COVID-19. There is a need for review of healthcare resources in rural hospitals which already face numerous healthcare challenges.
View article: Predictive Models for Weekly Cattle Mortality after Arrival at a Feeding Location Using Records, Weather, and Transport Data at Time of Purchase
Predictive Models for Weekly Cattle Mortality after Arrival at a Feeding Location Using Records, Weather, and Transport Data at Time of Purchase Open
Feedlot mortality negatively affects animal welfare and profitability. To the best of our knowledge, there are no publications on predictive models for weekly all-cause mortality in feedlot cattle. In this study, random forest models to pr…
View article: Predictors of Mortality for Patients with COVID-19 in the Rural Appalachian Region
Predictors of Mortality for Patients with COVID-19 in the Rural Appalachian Region Open
Huzefa Bhopalwala,1 Nakeya Dewaswala,2 Sandhya Kolagatla,1 Lauren Wisnieski,3 Jonathan Piercy,1 Adnan Bhopalwala,1 Nagabhishek Moka1 1Department of Internal Medicine, Appalachian Regional Healthcare, Whitesburg, KY, USA; 2Department of Car…
View article: Predictors of Mortality for Patients with COVID-19 in the Rural Appalachian Region
Predictors of Mortality for Patients with COVID-19 in the Rural Appalachian Region Open
The aging population, multiple co-morbidities, and health-related behaviors make rural patients vulnerable to COVID-19. A better understanding of the disease in rural areas is crucial, given its heightened vulnerability to adverse outcomes.
View article: COVID-19 Experiences, Behaviors, Beliefs, and Well-Being Among Students and Employees at a University In Rural Appalachia
COVID-19 Experiences, Behaviors, Beliefs, and Well-Being Among Students and Employees at a University In Rural Appalachia Open
Introduction: In response to the coronavirus disease (COVID-19) pandemic, most universities experienced drastic operational changes with shifts to online learning, work-from-home policies, and social distancing measures. These changes have…
View article: Serum Vitamin D Is Associated with Antioxidant Potential in Peri-Parturient Cows
Serum Vitamin D Is Associated with Antioxidant Potential in Peri-Parturient Cows Open
Dairy cows experience increased oxidative stress during periods of transition such as at the cessation of lactation and around the periparturient period, thus increasing disease risk. Despite routine supplementation of transition cow diets…
View article: COVID-19 Vaccine Acceptance Among Rural Appalachian Healthcare Workers (Eastern Kentucky/West Virginia): A Cross-Sectional Study
COVID-19 Vaccine Acceptance Among Rural Appalachian Healthcare Workers (Eastern Kentucky/West Virginia): A Cross-Sectional Study Open
Introduction The success of a vaccination program is dependent on vaccine efficacy and the number of people vaccinated. Healthcare workers are the first to receive the COVID-19 vaccine based on CDC phase 1a recommendations and are a point …
View article: Random-effects linear model application to herd-level assessment of bovine hepatic trace mineral concentrations
Random-effects linear model application to herd-level assessment of bovine hepatic trace mineral concentrations Open
To evaluate the utility of random-effects linear modeling for herd-level evaluation of trace mineral status, we performed a retrospective analysis of the results for trace mineral testing of bovine liver samples submitted to the Michigan S…
View article: Rumination time around dry-off relative to the development of diseases in early-lactation cows
Rumination time around dry-off relative to the development of diseases in early-lactation cows Open
Monitoring rumination time (RT) around the time of calving is an effective way of identifying cows at risk of disease in early lactation. However, this only allows for the identification of cows a few days before the onset of clinical sign…
View article: Changes in bovine leukemia virus serological status and lymphocyte count between dry-off and early lactation in Michigan dairy cows
Changes in bovine leukemia virus serological status and lymphocyte count between dry-off and early lactation in Michigan dairy cows Open
This study addresses how the serological status of bovine leukemia virus (BLV) and lymphocyte count fluctuate from dry-off to early lactation in dairy cattle. Very few studies have investigated how BLV antibody status and lymphocyte count …
View article: Serum vitamin D concentrations at dry-off and close-up predict increased postpartum urine ketone concentrations in dairy cattle
Serum vitamin D concentrations at dry-off and close-up predict increased postpartum urine ketone concentrations in dairy cattle Open
Vitamin D is commonly supplemented to dairy cows as vitamin D3 to support calcium homeostasis and in times of low sunlight exposure. Vitamin D has beneficial immunomodulatory and anti-inflammatory properties. Serum 25-hydroxyvit…
View article: Vitamin A and its association with inflammatory disease from dry off through the fresh period
Vitamin A and its association with inflammatory disease from dry off through the fresh period Open
Vitamin A is an essential nutrient and is well established to be crucial for regulating hematopoiesis, epithelial integrity, vision, and embryogenesis. In humans, vitamin A deficiency is associated with increased risk of morbidity, mortali…
View article: Cardiorespiratory Fitness as a Mediator of the Association between Physical Activity and Overweight and Obesity in Adolescent Girls
Cardiorespiratory Fitness as a Mediator of the Association between Physical Activity and Overweight and Obesity in Adolescent Girls Open
Background: Overweight and obesity (OW/OB) continue to be prominent health issues among adolescent girls. However, little is known about the interrelationships between physical activity (PA), cardiorespiratory fitness (CRF), …
View article: Changes in biomarkers of nutrient metabolism, inflammation, and oxidative stress in dairy cows during the transition into the early dry period
Changes in biomarkers of nutrient metabolism, inflammation, and oxidative stress in dairy cows during the transition into the early dry period Open
Metabolic stress occurs in dairy cows when physiologic homeostasis is disrupted as a consequence of aberrant nutrient metabolism, chronic inflammation, and oxidative stress. Early-lactation cows that suffer from metabolic stress are suscep…
View article: Reduced serum vitamin D concentrations in healthy early-lactation dairy cattle
Reduced serum vitamin D concentrations in healthy early-lactation dairy cattle Open
Cattle obtain vitamin D by ingestion or cutaneous exposure to UV light. Dairy cattle diets are frequently supplemented with vitamin D to compensate for limited sun exposure or during times of increased metabolic demands, such as the peripa…