Laurent Suissa
YOU?
Author Swipe
View article: Evaluation of Pleural Vents Inserted by Radiologists Versus Intercostal Chest Drains Managed by Respiratory Physicians for Post-CT-Guided Lung Biopsy Pneumothorax at Glan Clwyd Hospital, Wales
Evaluation of Pleural Vents Inserted by Radiologists Versus Intercostal Chest Drains Managed by Respiratory Physicians for Post-CT-Guided Lung Biopsy Pneumothorax at Glan Clwyd Hospital, Wales Open
View article: Impact of Food Exposome on Atherosclerotic Plaque Stability: Metabolomic Insights from Human Carotid Endarterectomy Specimen
Impact of Food Exposome on Atherosclerotic Plaque Stability: Metabolomic Insights from Human Carotid Endarterectomy Specimen Open
Carotid atherosclerotic stenosis (CAS) is a leading cause of ischemic stroke. Current understanding of plaque vulnerability remains largely confined to histopathological characterization. Consequently, identifying molecular determinants of…
View article: Evaluation of pleural vents vs indwelling chest drains for the management of post CT-guided biopsy pneumothorax by radiologists and respiratory physicians, at Glan Clwyd Hospital, Wales
Evaluation of pleural vents vs indwelling chest drains for the management of post CT-guided biopsy pneumothorax by radiologists and respiratory physicians, at Glan Clwyd Hospital, Wales Open
Introduction: Computed tomography (CT)-guided biopsy (CTGB) of the lung is a commonly used procedure for diagnosing lung cancer at Glan Clwyd Hospital. Pneumothorax is a known complication of CTGB with an incidence rate of ∼25%.1 Depending…
View article: Dynamics of Ionic and Cytotoxic Edema During Acute and Subacute Stages of Patients With Ischemic Stroke: Complementarity of <sup>23</sup>Na MRI and Diffusion MRI
Dynamics of Ionic and Cytotoxic Edema During Acute and Subacute Stages of Patients With Ischemic Stroke: Complementarity of <sup>23</sup>Na MRI and Diffusion MRI Open
Cerebral imaging is crucial in the diagnosis and treatment algorithm of acute stroke to determine salvageable brain tissue. While diffusion MRI is commonly used to define the ischemic core, it cannot reliably distinguish irreversibly damag…
View article: Added Value of Sodium MR Imaging and Proton MR Spectroscopy to Conventional MR Imaging for a Better Characterization of the Ischemic Stroke: A Narrative Review
Added Value of Sodium MR Imaging and Proton MR Spectroscopy to Conventional MR Imaging for a Better Characterization of the Ischemic Stroke: A Narrative Review Open
Stroke is a major cause of disability and death in adults worldwide. In clinical setting, time efficient MRI protocols including diffusion weighted images, fluid attenuated inversion recovery, fast T2*-weighted images and MR angiography ai…
View article: Reprint of: Scientific statement from the French neurovascular and cardiac societies for improved detection of atrial fibrillation after ischaemic stroke and transient ischaemic attack
Reprint of: Scientific statement from the French neurovascular and cardiac societies for improved detection of atrial fibrillation after ischaemic stroke and transient ischaemic attack Open
View article: Addendum to “Scientific statement from the French neurovascular and cardiac societies for improved detection of atrial fibrillation after ischaemic stroke and transient ischaemic attack” [Arch. Cardiovasc. Dis. 117 (2024) 542–557]
Addendum to “Scientific statement from the French neurovascular and cardiac societies for improved detection of atrial fibrillation after ischaemic stroke and transient ischaemic attack” [Arch. Cardiovasc. Dis. 117 (2024) 542–557] Open
View article: Scientific statement from the French neurovascular and cardiac societies for improved detection of atrial fibrillation after ischaemic stroke and transient ischaemic attack
Scientific statement from the French neurovascular and cardiac societies for improved detection of atrial fibrillation after ischaemic stroke and transient ischaemic attack Open
Atrial fibrillation (AF) is the primary cause of ischaemic stroke and transient ischaemic attack (TIA). AF is associated with a high risk of recurrence, which can be reduced using optimal prevention strategies, mainly anticoagulant therapy…
View article: How Clot Composition Influences Fibrinolysis in the Acute Phase of Stroke: A Proteomic Study of Cerebral Thrombi
How Clot Composition Influences Fibrinolysis in the Acute Phase of Stroke: A Proteomic Study of Cerebral Thrombi Open
BACKGROUND: The dramatic clinical improvement offered by mechanical thrombectomy raised questions about the relevance of prior intravenous thrombolysis in large-vessel occlusion strokes. Hence, studying intravenous thrombolysis susceptibil…
View article: Neuroprotective effects of lactate and ketone bodies in acute brain injury
Neuroprotective effects of lactate and ketone bodies in acute brain injury Open
The goal of neurocritical care is to prevent and reverse the pathologic cascades of secondary brain injury by optimizing cerebral blood flow, oxygen supply and substrate delivery. While glucose is an essential energetic substrate for the b…
View article: Symptomatic Carotid Free-Floating Thrombus: About Management of 50 Cases in a Referral Neurovascular Center
Symptomatic Carotid Free-Floating Thrombus: About Management of 50 Cases in a Referral Neurovascular Center Open
Background: Carotid free-floating thrombus (CFFT) is an uncommon disorder. The aim of this study was to describe a French cohort of CFFT patients. Methods: We conducted a retrospective monocentric study from a Stroke Center among patients …
View article: #2648 IMPACT OF ACUTE AND CHRONIC KIDNEY FUNCTION ON THE SIZE AND PROGNOSIS OF ISCHEMIC STROKE AFTER THROMBECTOMY
#2648 IMPACT OF ACUTE AND CHRONIC KIDNEY FUNCTION ON THE SIZE AND PROGNOSIS OF ISCHEMIC STROKE AFTER THROMBECTOMY Open
Background and Aims Patients with Chronic Kidney Disease (CKD) have an increased risk of ischemic and haemorrhagic stroke and CKD seem associated with worse outcome after a stroke. Few studies specifically investigated the impact of mechan…
View article: Atrial Fibrillation Detected by Implantable Monitor in Embolic Stroke of Undetermined Source: A New Clinical Entity
Atrial Fibrillation Detected by Implantable Monitor in Embolic Stroke of Undetermined Source: A New Clinical Entity Open
Background: High incidence of covert paroxysmal atrial fibrillation (CPAF) detected by an implantable cardiac monitor (ICM) is expected in embolic stroke of undetermined source (ESUS) patients. This study aimed to determine the CPAF rate i…
View article: Regional brain glucose metabolism is differentially affected by ketogenic diet: A human semiquantitative positron emission tomography
Regional brain glucose metabolism is differentially affected by ketogenic diet: A human semiquantitative positron emission tomography Open
Purpose Ketogenic diet (KD) is recommended to avoid intense [ 18 F]FDG myocardial physiologic uptake in PET imaging. Neuroprotective and anti-seizure effects of KD have been suggested, but their mechanisms remain to be elucidated. This [ 1…
View article: Combined Omic Analyzes of Cerebral Thrombi: A New Molecular Approach to Identify Cardioembolic Stroke Origin
Combined Omic Analyzes of Cerebral Thrombi: A New Molecular Approach to Identify Cardioembolic Stroke Origin Open
Background and Purpose: The diagnosis of cardioembolic stroke can be challenging for patient management in secondary stroke prevention, particularly in the case of covert paroxysmal atrial fibrillation. The molecular composition of a cereb…
View article: Prediction of Early Neurological Deterioration in Individuals With Minor Stroke and Large Vessel Occlusion Intended for Intravenous Thrombolysis Alone
Prediction of Early Neurological Deterioration in Individuals With Minor Stroke and Large Vessel Occlusion Intended for Intravenous Thrombolysis Alone Open
The substantial ENDi rates observed in these cohorts highlights the current debate regarding whether to directly transfer patients with IVT-treated minor stroke and LVO for additional thrombectomy. Based on the strong associations observed…
View article: Ingested Ketone Ester Leads to a Rapid Rise of Acetyl-CoA and Competes with Glucose Metabolism in the Brain of Non-Fasted Mice
Ingested Ketone Ester Leads to a Rapid Rise of Acetyl-CoA and Competes with Glucose Metabolism in the Brain of Non-Fasted Mice Open
The role of ketone bodies in the cerebral energy homeostasis of neurological diseases has begun to attract recent attention particularly in acute neurological diseases. In ketogenic therapies, ketosis is achieved by either a ketogenic diet…
View article: Intended Bridging Therapy or Intravenous Thrombolysis Alone in Minor Stroke With Basilar Artery Occlusion
Intended Bridging Therapy or Intravenous Thrombolysis Alone in Minor Stroke With Basilar Artery Occlusion Open
Background and Purpose: Whether bridging therapy (intravenous thrombolysis [IVT] followed by mechanical thrombectomy) is superior to IVT alone in minor stroke with basilar artery occlusion remains uncertain. Methods: Multicentric retrospec…
View article: Metabolome of Cerebral Thrombi Reveals an Association between High Glycemia at Stroke Onset and Good Clinical Outcome
Metabolome of Cerebral Thrombi Reveals an Association between High Glycemia at Stroke Onset and Good Clinical Outcome Open
Despite the fact that glucose is the main fuel of the brain, hyperglycemia at hospital admission is generally associated with a poor functional outcome in stroke patients. This paradox may be explained by the lack of information about the …
View article: Recurrence of ischemic stroke on direct oral anticoagulant therapy in a patient with marantic endocarditis related to lung cancer
Recurrence of ischemic stroke on direct oral anticoagulant therapy in a patient with marantic endocarditis related to lung cancer Open
View article: Urinary ketone body loss leads to degeneration of brain white matter in elderly SLC5A8-deficient mice
Urinary ketone body loss leads to degeneration of brain white matter in elderly SLC5A8-deficient mice Open
SLC5A8 is a sodium-coupled monocarboxylate and ketone transporter expressed in various epithelial cells. A putative role of SLC5A8 in neuroenergetics has been also hypothesized. To clarify this issue, we studied the cerebral phenotype of S…
View article: Angioedema associated with thrombolysis for ischemic stroke: analysis of a case‐control study
Angioedema associated with thrombolysis for ischemic stroke: analysis of a case‐control study Open
Background Bradykinin‐mediated angioedema (AE) is a complication associated with thrombolysis for acute ischemic stroke. Risk factors are unknown and management is discussed. Objectives To clarify risk factors associated with bradykinin‐me…
View article: Études des propriétés fonctionnelles et du rôle de la protéine membranaire SLC5A8
Études des propriétés fonctionnelles et du rôle de la protéine membranaire SLC5A8 Open
The functional properties of the SLC5A8 membrane protein and its physiological role have been studied in vitro and in vivo using slc5a8-/- mice. In vitro, analysis of metabolite uptake by LC-MS with slc5a8 transfected HEK cells to study so…
View article: Ischemic Stroke in a Young Patient Heralding a Left Ventricular Noncompaction Cardiomyopathy
Ischemic Stroke in a Young Patient Heralding a Left Ventricular Noncompaction Cardiomyopathy Open
Strokes in young patients may be the clinical expression of many complex and extremely rare diseases. Uncommon causes constitute less than 5% of all strokes, but are present in 30% of strokes in young patients. We report the case of a youn…
View article: Letter by Mahagne et al Regarding Article, “Embolic Strokes of Undetermined Source in the Athens Stroke Registry: A Descriptive Analysis”
Letter by Mahagne et al Regarding Article, “Embolic Strokes of Undetermined Source in the Athens Stroke Registry: A Descriptive Analysis” Open