Laurica A Petrella
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View article: P-196. Differences in <i>Clostridioides difficile</i> Molecular Epidemiology and Antimicrobial Susceptibility at Two Veterans Affairs Hospitals
P-196. Differences in <i>Clostridioides difficile</i> Molecular Epidemiology and Antimicrobial Susceptibility at Two Veterans Affairs Hospitals Open
Background Clostridioides difficile infections (CDI) are caused by a diverse group of strains with differences in prevalence and differing antimicrobial susceptibilities. Over the past 20 years the C. difficile (CD) molecular epidemiology …
View article: P-194. Evolution of <i>Clostridioides</i> difficile Antimicrobial Susceptibility within the epidemic REA Group BI (RT027) and the endemic REA group Y (RT014/020)
P-194. Evolution of <i>Clostridioides</i> difficile Antimicrobial Susceptibility within the epidemic REA Group BI (RT027) and the endemic REA group Y (RT014/020) Open
Background Antimicrobial resistance in Clostridioides difficile (CD) has been a key contributor for the spread of specific endemic CD strains. Monitoring changes in antimicrobial minimum inhibitor concentration (MIC) over time could potent…
View article: P-195. Clinical <i>Clostridioides difficile</i> Diagnostic Test Types and Results are Associated with the Likelihood of Recovering <i>C. difficile</i> in Stool Cultures
P-195. Clinical <i>Clostridioides difficile</i> Diagnostic Test Types and Results are Associated with the Likelihood of Recovering <i>C. difficile</i> in Stool Cultures Open
Background Active Clostridioides difficile infection (CDI) surveillance is conducted by the U.S. CDC’s Emerging Infections Program (EIP) and includes collection of a convenience sample of stool specimens from C. difficile positive cases. A…
View article: Epidemiology of <i>Clostridioides difficile</i> infection at one hospital 10 years after an outbreak of the epidemic <i>C. difficile</i> strain BI/027: changing strain prevalence, antimicrobial susceptibilities, and patient antibiotic exposures
Epidemiology of <i>Clostridioides difficile</i> infection at one hospital 10 years after an outbreak of the epidemic <i>C. difficile</i> strain BI/027: changing strain prevalence, antimicrobial susceptibilities, and patient antibiotic exposures Open
In contrast to the epidemiology 10 years earlier at our hospital when the epidemic restriction endonuclease analysis (REA) group strain BI accounted for 72% of Clostridioides difficile isolates recovered from first-episode C. difficile inf…
View article: 595. Recovery of <i>Clostridioides difficile</i> Isolates from Cary-Blair Transport Medium Compared to No Transport Medium
595. Recovery of <i>Clostridioides difficile</i> Isolates from Cary-Blair Transport Medium Compared to No Transport Medium Open
Background Surveillance of C. difficile infection (CDI), one of the most common U.S. healthcare-associated infections, is essential to inform public health response, characterize strains causing disease, and describe changes in strain prev…
View article: 406. Vancomycin Activity against Clostridioides difficile Over Three Decades in Chicago
406. Vancomycin Activity against Clostridioides difficile Over Three Decades in Chicago Open
Background In 2017, the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiologist of America (SHEA) updated the C. difficile (CD) treatment guidelines recommending vancomycin as the preferred therapy for C. di…
View article: 661. In vitro Activity of Omadacycline and Comparator Antibiotics against Clostridioides difficile
661. In vitro Activity of Omadacycline and Comparator Antibiotics against Clostridioides difficile Open
Background Omadacycline was approved for the treatment of community acquired bacterial pneumonia (CABP) and acute bacterial skin and skin structure infections (ABSSSI) in 2018. Previous studies demonstrate that omadacycline has in vitro ac…
View article: Can <i>Clostridium innocuum</i> Masquerade as <i>Clostridioides difficile?</i>
Can <i>Clostridium innocuum</i> Masquerade as <i>Clostridioides difficile?</i> Open
To the Editor—Darkoh et al [1] recently described high-level vancomycin resistance (≥32 μg/mL) in Clostridioides difficile isolates that were recovered from Houston, Texas, and Nairobi, Kenya. The authors concluded that C. difficile isolat…
View article: Unique Clindamycin-Resistant <i>Clostridioides</i><i>difficile</i> Strain Related to Fluoroquinolone-Resistant Epidemic BI/RT027 Strain
Unique Clindamycin-Resistant <i>Clostridioides</i><i>difficile</i> Strain Related to Fluoroquinolone-Resistant Epidemic BI/RT027 Strain Open
During a surveillance study of patients in a long-term care facility and the affiliated acute care hospital in the United States, we identified a Clostridioides difficile strain related to the epidemic PCR ribotype (RT) 027 strain associat…
View article: ICE volume 39 issue 8 Cover and Front matter
ICE volume 39 issue 8 Cover and Front matter Open
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