Lawrence A. Shirley
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View article: SUN-257 Point-of-Care Oxidative Stress Profiling Reveals Distinct Inflammatory Subgroups in Subjects with Cardiometabolic Risks
SUN-257 Point-of-Care Oxidative Stress Profiling Reveals Distinct Inflammatory Subgroups in Subjects with Cardiometabolic Risks Open
Disclosure: R. Dalan: None. A.T. Alves: LarmorBIO. L. Shirley: None. C. Ying Jie: None. M.J. McPhaul: LarmorBIO. R. Rohr: LarmorBIO. B.O. Boehm: LarmorBIO. Oxidative stress plays a crucial role in the pathogenesis of cardiometabolic diseas…
View article: SUN-257 Point-of-Care Oxidative Stress Profiling Reveals Distinct Inflammatory Subgroups in Subjects with Cardiometabolic Risks
SUN-257 Point-of-Care Oxidative Stress Profiling Reveals Distinct Inflammatory Subgroups in Subjects with Cardiometabolic Risks Open
Disclosure: R. Dalan: None. A.T. Alves: LarmorBIO. L. Shirley: None. C. Ying Jie: None. M.J. McPhaul: LarmorBIO. R. Rohr: LarmorBIO. B.O. Boehm: LarmorBIO. Oxidative stress plays a crucial role in the pathogenesis of cardiometabolic diseas…
View article: Supplementary Methods, Figures 1-4 from Alternative Cyclin D1 Splice Forms Differentially Regulate the DNA Damage Response
Supplementary Methods, Figures 1-4 from Alternative Cyclin D1 Splice Forms Differentially Regulate the DNA Damage Response Open
Supplementary Methods, Figures 1-4 from Alternative Cyclin D1 Splice Forms Differentially Regulate the DNA Damage Response
View article: Supplementary Figures 1-5 from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion
Supplementary Figures 1-5 from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion Open
Supplementary Figures 1-5 from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion
View article: Supplementary Figure Legends 1-5 from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion
Supplementary Figure Legends 1-5 from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion Open
Supplementary Figure Legends 1-5 from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion
View article: Supplementary Figure Legends 1-5 from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion
Supplementary Figure Legends 1-5 from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion Open
Supplementary Figure Legends 1-5 from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion
View article: Supplementary Methods from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion
Supplementary Methods from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion Open
Supplementary Methods from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion
View article: Supplementary Figures 1-5 from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion
Supplementary Figures 1-5 from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion Open
Supplementary Figures 1-5 from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion
View article: Supplementary Tables 1-2 from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion
Supplementary Tables 1-2 from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion Open
Supplementary Tables 1-2 from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion
View article: Data from Alternative Cyclin D1 Splice Forms Differentially Regulate the DNA Damage Response
Data from Alternative Cyclin D1 Splice Forms Differentially Regulate the DNA Damage Response Open
The DNA damage response (DDR) activates downstream pathways including cell cycle checkpoints. The cyclin D1 gene is overexpressed or amplified in many human cancers and is required for gastrointestinal, breast, and skin tumors in mu…
View article: Data from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion
Data from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion Open
The role of mammary epithelial cell (MEC) NF-κB in tumor progression in vivo is unknown, as murine NF-κB components and kinases either are required for murine survival or interfere with normal mammary gland development. As NF-κB inh…
View article: Supplementary Tables 1-2 from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion
Supplementary Tables 1-2 from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion Open
Supplementary Tables 1-2 from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion
View article: Data from Single-Cell Transcription Site Activation Predicts Chemotherapy Response in Human Colorectal Tumors
Data from Single-Cell Transcription Site Activation Predicts Chemotherapy Response in Human Colorectal Tumors Open
Candidate gene and pathway approaches, and unbiased gene expression profiling, have identified marker signatures predictive of tumor phenotypes, such as drug sensitivity and invasive or metastatic potential. However, application of such in…
View article: Data from Alternative Cyclin D1 Splice Forms Differentially Regulate the DNA Damage Response
Data from Alternative Cyclin D1 Splice Forms Differentially Regulate the DNA Damage Response Open
The DNA damage response (DDR) activates downstream pathways including cell cycle checkpoints. The cyclin D1 gene is overexpressed or amplified in many human cancers and is required for gastrointestinal, breast, and skin tumors in mu…
View article: Supplementary Figure 1 from Single-Cell Transcription Site Activation Predicts Chemotherapy Response in Human Colorectal Tumors
Supplementary Figure 1 from Single-Cell Transcription Site Activation Predicts Chemotherapy Response in Human Colorectal Tumors Open
Supplementary Figure 1 from Single-Cell Transcription Site Activation Predicts Chemotherapy Response in Human Colorectal Tumors
View article: Supplementary Methods from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion
Supplementary Methods from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion Open
Supplementary Methods from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion
View article: Data from Single-Cell Transcription Site Activation Predicts Chemotherapy Response in Human Colorectal Tumors
Data from Single-Cell Transcription Site Activation Predicts Chemotherapy Response in Human Colorectal Tumors Open
Candidate gene and pathway approaches, and unbiased gene expression profiling, have identified marker signatures predictive of tumor phenotypes, such as drug sensitivity and invasive or metastatic potential. However, application of such in…
View article: Data from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion
Data from The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion Open
The role of mammary epithelial cell (MEC) NF-κB in tumor progression in vivo is unknown, as murine NF-κB components and kinases either are required for murine survival or interfere with normal mammary gland development. As NF-κB inh…
View article: Supplementary Methods, Figures 1-4 from Alternative Cyclin D1 Splice Forms Differentially Regulate the DNA Damage Response
Supplementary Methods, Figures 1-4 from Alternative Cyclin D1 Splice Forms Differentially Regulate the DNA Damage Response Open
Supplementary Methods, Figures 1-4 from Alternative Cyclin D1 Splice Forms Differentially Regulate the DNA Damage Response
View article: Supplementary Figure 1 from Single-Cell Transcription Site Activation Predicts Chemotherapy Response in Human Colorectal Tumors
Supplementary Figure 1 from Single-Cell Transcription Site Activation Predicts Chemotherapy Response in Human Colorectal Tumors Open
Supplementary Figure 1 from Single-Cell Transcription Site Activation Predicts Chemotherapy Response in Human Colorectal Tumors
View article: Comparing intraoperative parathyroid identification based on surgeon experience versus near infrared autofluorescence detection – A surgeon-blinded multi-centric study
Comparing intraoperative parathyroid identification based on surgeon experience versus near infrared autofluorescence detection – A surgeon-blinded multi-centric study Open
View article: Prevalence of cancer and the benign call rate of afirma gene classifier in <sup>18</sup>F‐Fluorodeoxyglucose positron emission tomography positive cytologically indeterminate thyroid nodules
Prevalence of cancer and the benign call rate of afirma gene classifier in <sup>18</sup>F‐Fluorodeoxyglucose positron emission tomography positive cytologically indeterminate thyroid nodules Open
Background 18 F‐Fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) positive (PET+) cytologically indeterminate thyroid nodules (ITNs) have variable cancer risk in the literature. The benign call rate (BCR) o…
View article: Prognosis of Macrophage Density in the Absence of Neutrophils in Differentiated Thyroid Cancer
Prognosis of Macrophage Density in the Absence of Neutrophils in Differentiated Thyroid Cancer Open
View article: Metastatic Adrenocortical Carcinoma: a Single Institutional Experience
Metastatic Adrenocortical Carcinoma: a Single Institutional Experience Open
View article: Intraoperative Autofluorescence Parathyroid Identification in Patients With Multiple Endocrine Neoplasia Type 1
Intraoperative Autofluorescence Parathyroid Identification in Patients With Multiple Endocrine Neoplasia Type 1 Open
Intraoperative identification of parathyroid glands using their autofluorescence by real-time NIR imaging appears to have utility in patients with primary hyperparathyroidism. In this initial cohort of patients with MEN1, decreased parathy…
View article: Afirma Gene Sequencing Classifier Compared with Gene Expression Classifier in Indeterminate Thyroid Nodules
Afirma Gene Sequencing Classifier Compared with Gene Expression Classifier in Indeterminate Thyroid Nodules Open
Background: The Afirma Gene Expression Classifier (GEC) has been used to further characterize cytologically indeterminate (cyto-I) thyroid nodules into either benign or suspicious categories. However, its relatively low posit…
View article: Long-Term Efficacy of Lymph Node Reoperation for Persistent Papillary Thyroid Cancer: 13-Year Follow-Up
Long-Term Efficacy of Lymph Node Reoperation for Persistent Papillary Thyroid Cancer: 13-Year Follow-Up Open
View article: Retraction: Targeting the Warburg effect with a novel glucose transporter inhibitor to overcome gemcitabine resistance in pancreatic cancer cells
Retraction: Targeting the Warburg effect with a novel glucose transporter inhibitor to overcome gemcitabine resistance in pancreatic cancer cells Open
View article: The Adrenal Gland as a Sanctuary Site of Metastases After Pembrolizumab Treatment: A Case Series
The Adrenal Gland as a Sanctuary Site of Metastases After Pembrolizumab Treatment: A Case Series Open
Therapeutic agents targeting the PD-1/PD-L1 axis have shown durable clinical responses in patients with various cancer types. Although objective responses are common, intrapatient heterogeneous responses have been described, and the mechan…
View article: Role of Additional Organ Resection in Adrenocortical Carcinoma: Analysis of 167 Patients from the U.S. Adrenocortical Carcinoma Database
Role of Additional Organ Resection in Adrenocortical Carcinoma: Analysis of 167 Patients from the U.S. Adrenocortical Carcinoma Database Open