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View article: Chemical Digestion-Assisted Proteomics Reveals the Extracellular Matrix Profile of Human Periodontal Ligament and its Alterations in Cultured Cell-Derived Extracellular Matrix
Chemical Digestion-Assisted Proteomics Reveals the Extracellular Matrix Profile of Human Periodontal Ligament and its Alterations in Cultured Cell-Derived Extracellular Matrix Open
The extracellular matrix (ECM) plays a crucial role in tissue structure and function and serves as an integral component of diverse biological systems. However, the comprehensive characterization of ECM components is challenging because of…
View article: Wnt/β-catenin Promotes Cementum Apposition in Periodontal Regeneration
Wnt/β-catenin Promotes Cementum Apposition in Periodontal Regeneration Open
Regeneration of periodontal tissue, particularly the cementum–periodontal ligament (PDL)–bone complex, has long been challenging because the differentiation kinetics of cells and the molecular pathways contributing to the regeneration proc…
View article: Acellular Extrinsic Fiber Cementum Is Invariably Present in the Superficial Layer of Apical Cementum in Mouse Molar
Acellular Extrinsic Fiber Cementum Is Invariably Present in the Superficial Layer of Apical Cementum in Mouse Molar Open
The cementum is a highly mineralized tissue that covers the tooth root. The regional differences among the types of cementum, especially in the extrinsic fibers that contribute to tooth support, remain controversial. Therefore, this study …
View article: Multiomics analysis of cultured mouse periodontal ligament cell-derived extracellular matrix
Multiomics analysis of cultured mouse periodontal ligament cell-derived extracellular matrix Open
A comprehensive understanding of the extracellular matrix (ECM) is essential for developing biomimetic ECM scaffolds for tissue regeneration. As the periodontal ligament cell (PDLC)-derived ECM has shown potential for periodontal tissue re…
View article: Extracellular Matrix-Oriented Proteomic Analysis of Periodontal Ligament Under Mechanical Stress
Extracellular Matrix-Oriented Proteomic Analysis of Periodontal Ligament Under Mechanical Stress Open
The periodontal ligament (PDL) is a specialized connective tissue that provides structural support to the tooth and is crucial for oral functions. The mechanical properties of the PDL are mainly derived from the tissue-specific composition…