Lea Separovic
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View article: Measles seroprevalence by birth cohort across the lifespan: a population-based, cross-sectional serosurvey in British Columbia, Canada
Measles seroprevalence by birth cohort across the lifespan: a population-based, cross-sectional serosurvey in British Columbia, Canada Open
Our measles serosurvey findings inform vaccine coverage and complement other case-based surveillance indicating robust population-level immunity outside of unvaccinated clusters or communities. In addition to showing age-related antibody d…
View article: Effectiveness of 2024/25 KP.2 vaccine against outpatient COVID-19 in Canada
Effectiveness of 2024/25 KP.2 vaccine against outpatient COVID-19 in Canada Open
Between November 2024 and April 2025, the Canadian Sentinel Practitioner Surveillance Network assessed KP.2 vaccine effectiveness against outpatient COVID-19 by test-negative design. Vaccination protected best during the first two months, …
View article: Neuraminidase imprinting and the age-related risk of zoonotic influenza
Neuraminidase imprinting and the age-related risk of zoonotic influenza Open
Highly pathogenic avian influenza of the H5N1 subtype has shown recent unprecedented expansion in its geographic and host range, increasing the pandemic threat. The younger age of H5N1 versus H7N9 avian influenza in humans has previously b…
View article: Cost-Effectiveness of Infant and Maternal RSV Immunization Strategies, in British Columbia, Canada
Cost-Effectiveness of Infant and Maternal RSV Immunization Strategies, in British Columbia, Canada Open
Background Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infections in young children and results in significant healthcare burden and costs. To reduce the impact of RSV in this population, the monoclonal …
View article: Interim estimates of vaccine effectiveness against influenza A(H1N1)pdm09 and A(H3N2) during a delayed influenza season, Canada, 2024/25
Interim estimates of vaccine effectiveness against influenza A(H1N1)pdm09 and A(H3N2) during a delayed influenza season, Canada, 2024/25 Open
The Canadian Sentinel Practitioner Surveillance Network (SPSN) reports interim 2024/25 vaccine effectiveness (VE) against acute respiratory illness due to laboratory-confirmed influenza during a delayed season of predominant A(H1N1)pdm09 a…