Leah Antoinette M. Caro-Chang
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View article: Epidermal spongiotic Langerhans cell collections, but not eosinophils, are a clue to the diagnosis of allergic contact dermatitis: A series of 170 clinically- and patch test-confirmed cases
Epidermal spongiotic Langerhans cell collections, but not eosinophils, are a clue to the diagnosis of allergic contact dermatitis: A series of 170 clinically- and patch test-confirmed cases Open
This largest study to date is the first to independently confirm Langerhans cell collections as the single histopathologic feature most closely associated with allergic contact dermatitis.
View article: Infliximab-induced amicrobial pustulosis of the folds in a patient with Crohn disease
Infliximab-induced amicrobial pustulosis of the folds in a patient with Crohn disease Open
Tumor necrosis factor (TNF) inhibitors may paradoxically induce pustular eruptions, most of which are classified as pustular psoriasis. Amicrobial pustulosis of the folds (APF) is a much rarer entity that was recently recognized to occur i…
View article: Eosinophils in psoriasis: A systematic review and meta‐analysis introducing a study quality assessment tool for diagnostic pathology studies
Eosinophils in psoriasis: A systematic review and meta‐analysis introducing a study quality assessment tool for diagnostic pathology studies Open
Background The histopathologic features of psoriasis are well‐documented, but recent studies have highlighted atypical features, such as eosinophils, in clinically confirmed cases. Methods A systematic review exploring eosinophils in psori…
View article: Localized calcium oxalate crystals in primary cutaneous aspergillosis
Localized calcium oxalate crystals in primary cutaneous aspergillosis Open
Select Aspergillus species can produce oxalate as a fermentation byproduct, which may react with calcium ions to produce insoluble calcium oxalate crystals in tissues. These crystals are frequently associated with pulmonary Aspergillus inf…
View article: The role of eosinophils in the differential diagnosis of inflammatory skin diseases
The role of eosinophils in the differential diagnosis of inflammatory skin diseases Open
Eosinophils are known to be present in inflammatory skin diseases, but their diagnostic utility is not well established. Upon review of the published status of lesional eosinophils, several categories were identified. 1) Lesional eosinophi…
View article: AIDS-Related Kaposi Sarcoma in a Tertiary University Hospital in Manila, Philippines: A Report of Six Cases
AIDS-Related Kaposi Sarcoma in a Tertiary University Hospital in Manila, Philippines: A Report of Six Cases Open
We report six cases of Kaposi sarcoma (KS) seen at the University of the Philippines–Philippine General Hospital, a tertiary university hospital with a 1,500-bed capacity in Manila, from 2017 to February 2020. All cases involved males (21–…
View article: Combination of Excimer Laser and Topical Treatment for Psoriasis: A Systematic Review and Meta-analysis
Combination of Excimer Laser and Topical Treatment for Psoriasis: A Systematic Review and Meta-analysis Open
Objectives. To assess the efficacy and safety of excimer laser in combination with topical standard therapies for treatment of plaque-type psoriasis in comparison to excimer laser alone, standard topical treatment alone, or placebo.
Metho…
View article: A Case of Cutaneous Tuberculosis Presenting with Generalized Xanthogranulomas
A Case of Cutaneous Tuberculosis Presenting with Generalized Xanthogranulomas Open
A 33-year-old male had a 22-year history of generalized xanthogranulomas but had a normal lipid profile. He also developed ulcerating plaques on his arm and back that were consistent with cutaneous tuberculosis on histopathologic and polym…
View article: Androgenetic Alopecia and its Association with Metabolic Syndrome: A Systematic Review and Meta-analysis
Androgenetic Alopecia and its Association with Metabolic Syndrome: A Systematic Review and Meta-analysis Open
Objectives. The study aimed to confirm the association between androgenetic alopecia (AGA) and Metabolic Syndrome (MetS). It also aimed to determine if early-onset AGA among males and AGA among females increases the risk of developing MetS…
View article: Multiple Neurofibromas with Hypertrichosis in a Filipino Patient with Neurofibromatosis 1
Multiple Neurofibromas with Hypertrichosis in a Filipino Patient with Neurofibromatosis 1 Open
This is a case of an 11-year-old male who presented with multiple neurofibromas with hypertrichosis. Classic cutaneous neurofibromas, café-au-lait macules, axillary freckling, Lisch nodules, and scoliosis were also present fulfilling a dia…