Leah Vines
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View article: Rest-Activity Rhythms, Their Modulators, and Brain-Clinical Correlates in Opioid Use Disorder
Rest-Activity Rhythms, Their Modulators, and Brain-Clinical Correlates in Opioid Use Disorder Open
Importance Sleep and circadian disruptions are highly prevalent in opioid use disorder (OUD) and are a barrier to successful treatment and recovery; yet few objective data are available, especially for individuals in OUD treatment with opi…
View article: Changes in rest-activity rhythms in adolescents as they age: associations with brain changes and behavior in the ABCD study
Changes in rest-activity rhythms in adolescents as they age: associations with brain changes and behavior in the ABCD study Open
Background Adolescents with disrupted rest-activity rhythms (RAR) including shorter sleep duration, later sleep timing and low physical activity levels have higher risk for mental and behavioral problems. However, it remains unclear whethe…
View article: Neurological, Behavioral, and Pathophysiological Characterization of the Co-Occurrence of Substance Use and HIV: A Narrative Review
Neurological, Behavioral, and Pathophysiological Characterization of the Co-Occurrence of Substance Use and HIV: A Narrative Review Open
Combined antiretroviral therapy (cART) has greatly reduced the severity of HIV-associated neurocognitive disorders in people living with HIV (PLWH); however, PLWH are more likely than the general population to use drugs and suffer from sub…
View article: Age-related differences in striatal dopamine D1 receptors mediate subjective drug effects
Age-related differences in striatal dopamine D1 receptors mediate subjective drug effects Open
To the Editor: The brain's dopamine system is critical for cognition, reward, and motivation.It plays a crucial role in the reinforcing effects of drugs with addiction potential as well as in some of their therapeutic effects (e.g., stimul…
View article: Elevated emotion reactivity and emotion regulation in individuals at clinical high risk for developing psychosis and those diagnosed with a psychotic disorder
Elevated emotion reactivity and emotion regulation in individuals at clinical high risk for developing psychosis and those diagnosed with a psychotic disorder Open
Aims Disrupted affective processes are core features of psychosis; yet emotion reactivity and emotion regulation impairments have not been fully characterized in individuals at clinical high‐risk for developing psychosis (CHR) or adolescen…