Leandro M. O. Lourenço
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View article: Carbon dot–phthalocyanine hybrids: synergistic effects that boost their multifaceted applications
Carbon dot–phthalocyanine hybrids: synergistic effects that boost their multifaceted applications Open
This review covers recent advances in Pc@CD hybrids, emphasizing synthesis, conjugation strategies, and enhanced properties that drive applications in sensing, electrocatalysis, phototherapy, and photocatalysis.
View article: Unveiling the potent antimicrobial photodynamic therapy in Gram-positive and Gram-negative bacteria – Water remediation with monocharged chlorins
Unveiling the potent antimicrobial photodynamic therapy in Gram-positive and Gram-negative bacteria – Water remediation with monocharged chlorins Open
Water pollution is a significant concern worldwide, and it includes contaminants such as antibiotic-resistant pathogens. Antimicrobial photodynamic therapy (aPDT) offers a non-invasive and non-toxic alternative for the inactivation of thes…
View article: Exploring the spectral properties and potential applications of dimethylamine-modified porphyrin and chlorin dyes
Exploring the spectral properties and potential applications of dimethylamine-modified porphyrin and chlorin dyes Open
The synthesis, structural characterization, and optical properties of new free-base and metalated dimethylamine-based porphyrin (1, 1a) and chlorin (2, 2a) derivatives are presented. The synthetic approach is based on the peripheral substi…
View article: Localized cancer photodynamic therapy approach based on core–shell electrospun nanofibers
Localized cancer photodynamic therapy approach based on core–shell electrospun nanofibers Open
Core–shell nanofibers loaded with porphyrin were produced to act as localized DDS for treating cervical cancer using PDT. Porphyrin-loaded electrospun nanofibers showed a higher phototoxic effect against tumor cells compared to non-tumor o…
View article: Porphyrin-containing materials for photodegradation of organic pollutants in wastewaters: a review
Porphyrin-containing materials for photodegradation of organic pollutants in wastewaters: a review Open
Industrialization and town urbanization have led to an exponential need for clean water and new wastewater treatment strategies.
View article: Editorial: Photodynamic Therapy as an Important Tool for Biological Breakthroughs—Photoactive Photosensitizers Applied from Cancer to Microbial Targets
Editorial: Photodynamic Therapy as an Important Tool for Biological Breakthroughs—Photoactive Photosensitizers Applied from Cancer to Microbial Targets Open
Photodynamic therapy (PDT) stands as an approved clinical treatment for both oncologic and nononcologic disorders [...]
View article: Light-Driven Tetra- and Octa-β-substituted Cationic Zinc(II) Phthalocyanines for Eradicating Fusarium oxysporum Conidia
Light-Driven Tetra- and Octa-β-substituted Cationic Zinc(II) Phthalocyanines for Eradicating Fusarium oxysporum Conidia Open
Photodynamic inactivation (PDI) is an emerging therapeutic approach that can effectively inactivate diverse microbial forms, including vegetative forms and spores, while preserving host tissues and avoiding the development of resistance to…
View article: Photodynamic inactivation of a RNA-virus model using water-soluble β-octa-Substituted pyridinium-pyrazolyl phthalocyanines
Photodynamic inactivation of a RNA-virus model using water-soluble β-octa-Substituted pyridinium-pyrazolyl phthalocyanines Open
Among the various groups of microorganisms, viruses have generally a greater capacity for mutation, especially RNA viruses, as was demonstrated by SARS-CoV2 virus mutations. This high mutation rate promotes the development of their resista…
View article: Thin film and surface preparation chamber for the low energy muons spectrometer
Thin film and surface preparation chamber for the low energy muons spectrometer Open
We have designed and constructed a thin film preparation chamber with base pressure of <2×10 −9 mbar. Currently, the chamber is equipped with two large area evaporators (a molecular evaporator and an electron-beam evaporator), an ion sputt…
View article: In Vitro Photoinactivation of Fusarium oxysporum Conidia with Light-Activated Ammonium Phthalocyanines
In Vitro Photoinactivation of Fusarium oxysporum Conidia with Light-Activated Ammonium Phthalocyanines Open
Antimicrobial photodynamic therapy (aPDT) has been explored as an innovative therapeutic approach because it can be used to inactivate a variety of microbial forms (vegetative forms and spores) without causing significant damage to host ti…
View article: Advances in photocatalytic degradation of organic pollutants in wastewaters: harnessing the power of phthalocyanines and phthalocyanine-containing materials
Advances in photocatalytic degradation of organic pollutants in wastewaters: harnessing the power of phthalocyanines and phthalocyanine-containing materials Open
Access to clean water is increasingly challenging worldwide due to human activities and climate change.
View article: Editorial: Next generation nanomaterials for photodynamic therapy
Editorial: Next generation nanomaterials for photodynamic therapy Open
EDITORIAL article Front. Chem., 21 December 2022Sec. Nanoscience Volume 10 - 2022 | https://doi.org/10.3389/fchem.2022.1123216
View article: Thin film and surface preparation chamber for the low energy muons spectrometer
Thin film and surface preparation chamber for the low energy muons spectrometer Open
We have designed and constructed a thin film preparation chamber with base pressure of $<2 \times 10^{-9}$~mbar. Currently, the chamber is equipped with two large area evaporators (a molecular evaporator and an electron-beam evaporator), a…
View article: Coelenterazine Derivatives as Potential Drugs for Photodynamic Therapy
Coelenterazine Derivatives as Potential Drugs for Photodynamic Therapy Open
Cancer is one of the main leading causes of death worldwide, and its treatment is highly complex and known to cause serious side effects for patients. Photodynamic therapy (PDT) has gained a worldwide impact as a promising alternative stra…
View article: Anti-Viral Photodynamic Inactivation of T4-like Bacteriophage as a Mammalian Virus Model in Blood
Anti-Viral Photodynamic Inactivation of T4-like Bacteriophage as a Mammalian Virus Model in Blood Open
The laboratorial available methods applied in plasma disinfection can induce damage in other blood components. Antimicrobial photodynamic therapy (aPDT) represents a promising approach and is approved for plasma and platelet disinfection u…
View article: Interfacial assembly of zinc(II) phthalocyanines on graphene oxide (GO): Stable “turn-off-on” nanoplatforms to detect G-quadruplexes (G4)
Interfacial assembly of zinc(II) phthalocyanines on graphene oxide (GO): Stable “turn-off-on” nanoplatforms to detect G-quadruplexes (G4) Open
GO induced a re-organization of the ZnPcs mostly to J-aggregates and quenched their original fluorescence up to 98 % ("turn-off"). In general, ZnPcs@GO recovered their fluorescence ("turn-on") after the titrations and showed affinity to G4…
View article: Graphene Quantum Dots and Phthalocyanines Turn-OFF-ON Photoluminescence Nanosensor for ds-DNA
Graphene Quantum Dots and Phthalocyanines Turn-OFF-ON Photoluminescence Nanosensor for ds-DNA Open
Supramolecular hybrids of graphene quantum dots (GQDs) and phthalocyanine (Pc) dyes were studied as turn-OFF-ON photoluminescence nanosensors for detection of ds-DNA. Pcs with four (Pc4) and eight (Pc8) positive charges were selected to in…
View article: The Antimicrobial Photoinactivation Effect on Escherichia coli through the Action of Inverted Cationic Porphyrin–Cyclodextrin Conjugates
The Antimicrobial Photoinactivation Effect on Escherichia coli through the Action of Inverted Cationic Porphyrin–Cyclodextrin Conjugates Open
Photodynamic action has been used for diverse biomedical applications, such as treating a broad range of bacterial infections. Based on the combination of light, dioxygen, and photosensitizer (PS), the photodynamic inactivation (PDI) appro…
View article: The Surprisingly Positive Effect of Zinc-Phthalocyanines With High Photodynamic Therapy Efficacy of Melanoma Cancer
The Surprisingly Positive Effect of Zinc-Phthalocyanines With High Photodynamic Therapy Efficacy of Melanoma Cancer Open
Phthalocyanine (Pc) dyes are photoactive molecules that can absorb and emit light in the visible spectrum, especially in the red region of the spectrum, with great potential for biological scopes. For this target, it is important to guaran…
View article: Multicharged Phthalocyanines as Selective Ligands for G-Quadruplex DNA Structures
Multicharged Phthalocyanines as Selective Ligands for G-Quadruplex DNA Structures Open
The stabilization of G-Quadruplex DNA structures by ligands is a promising strategy for telomerase inhibition in cancer therapy since this enzyme is responsible for the unlimited proliferation of cancer cells. To assess the potential of a …
View article: Photoinactivation of Planktonic and Biofilm Forms of <i>Escherichia coli</i> through the Action of Cationic Zinc(II) Phthalocyanines
Photoinactivation of Planktonic and Biofilm Forms of <i>Escherichia coli</i> through the Action of Cationic Zinc(II) Phthalocyanines Open
Novel water‐soluble zinc(II) phthalocyanines (ZnPc) peripherally substituted with 4‐dimethylaminopyridine (DMAP) units (ZnPc 1 – 2 ) and the corresponding quaternized derivatives (ZnPc 1 a – 2 a ) were synthesized and their photodynamic in…